Publications for Elisabeth Martinez

 Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, Easmon J, Martinez, E.D.. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun. 2013;4:2035. PMID- 23792809

Hu, Y., Martinez, E.D. and MacMillan, J. Anthraquinones from a marine-derived Streptomyces spinoverrucosus. J Nat Prod. 2012 Oct 26;75(10):1759-64. PMID:23057874

Chang, J., Varghese, D.S., Gillam, M.C., Peyton, M., Modi, B., Schiltz, R.L., Girard, L., and Martinez, E.D. Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide, (2012), British Journal of Cancer, Jan 3;106(1):116-25. Epub 2011 Dec 8. PMCID: PMC Journal-In Process.

Best, A., Chang, J., Dull, A., Beutler, J. and Martinez, E.D. Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell based assay, (2011), Journal of Biomedicine and Biotechnology, 2011:868095. Epub 2010 Dec 22. PMCID: PMC3014726

Holbeck, S., Chang, J., Best, A.M., Bookout, A.L., Mangelsdorf, D.J. and Martinez, E.D. Expression Profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions, (2010), Mol Endocrinol. 24(6):1287-96. PMID: 20375240. PMCID: PMC2875807.

Slack, M.D., Martinez, E.D., Wu, L.F. and Altschuler, S.J. Characterizing heterogeneous cellular responses to perturbations (2008), PNAS 105 (49):19306-11. PMID: 19052231. PMCID: PMC2614757.

Johnson, R.J., Huang, W., Jadhav, A., Austin, C.P., Inglese, J. and Martinez, E.D. A Quantitative High-Throughput Screen Identifies Potential Epigenetic Modulators of Gene Expression, (2008), Analytical Biochemistry 375(2):237-48. PMID: 18211814. PMCID: PMC2330280.

Martinez, E.D., Botos J., Dohoney K.M., Geiman T.M.,Kolla S.S., Olivera A., Qiu Y., Rayasam G.V., Stavreva D.A., Cohen-Fix O. Falling off the academic bandwagon. Women are more likely to quit at the postdoc to principal investigator transition, (2007), EMBO Rep. 11:977-981.

Martinez, E.D., Dull, A., McMahon, J., Beutler, J. and Hager, G.L., High content fluorescence-based screening for epigenetic modulators, (2006), Methods in Enzymol. 414:21-36. PMID: 17110184.

Martinez, E.D. and Hager, G.L. Development of assays for nuclear receptor ligands using fluorescently tagged proteins, (2006), Methods in Enzymol. 414:37-50. PMID: 17110185.

Auld, D.S., Johnson, R.L., Zhang, Y.,  Veith, H., Jadhav, A., Yasgar, A.,  Simeonov, A., Zheng, W., Martinez, E.D., Westwick, J.K., Austin, C.P., and Inglese, J. Fluorescent protein-based cellular assays analyzed by laser scanning microplate cytometry in 1536-well plate format, (2006), Methods in Enzymol. 414:566-589. PMID: 17110211.

Qiu, Y., Zhao, Y., Becker, M., John, S., Parekh, B.S., Huang, S., Hendarwanto, A., Martinez, E.D., Chen, Y., Lu, H., Adkins, N.L., Stavreva, D.A., Wiench, M., Georgel, P.T., Schiltz, R.L., and Hager, G.L. HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription, (2006), Molecular Cell 22:669-679. PMID: 16762839.

Martinez, E.D., Rayasam, G., Dull, A., Walker, D. and Hager, G.L. An Estrogen Receptor Chimera Senses Ligands by Nuclear Translocation (2005), J Steroid Biochem Mol Biol 97(4):307-321. PMID: 16162406.

Martinez, E.D., Pattabiraman, N. and Danielsen, M. Analysis of the hormone binding domain of steroid receptors using chimeras generated by homologous recombination (2005), Exp. Cell Research 308(2):320-33. PMID: 15936754.

Nagaich, A.K., Rayasam, G.V., Martinez, E.D., Becker, M., Qiu, Y., Johnson, T.A., Elbi, C., Fletcher, T.M., John, S., and Hager, G.L. Subnuclear Trafficking and Gene Targeting by Steroid Receptors (2004), Ann N.Y. Acad. Sci. 1024:213-220. PMID: 15265783.

Tirado, O.M., Martinez, E.D., Rodriguez, O.C., Danielsen, M., Selva, D.M., Reventos, J., Munell, F. and Suarez-Quian, C.A. Short-term effects of Methoxyacetic Acid on Androgen Receptor and Androgen-Binding Protein Expression in Adult Rat Testis (2003), Biol Reprod 68(4):1437-1446.  PMID: 12606434.

Martinez, E.D. and Danielsen, M. Loss of androgen receptor transcriptional activity at the G1/S transition: involvement of acetylation pathways (2002), Journal of Biological Chemistry 277(33):29719-29729. PMID: 12055183.

List, H.J, Smith, C., Martinez, E.D., Harris, V., Danielsen, M. and Riegel, A. Effects of Antiandrogens on Chromatin Remodeling and Transcription of the Integrated Mouse Mammary Tumor Virus Promoter (2000), Exp. Cell Research 260:160-165. PMID: 11010820.

Martinez, E., Moore, D., Keller, E., Pearce, D., Vanden Heuvel, J.P., Robinson, V., Gottlieb, B., McDonald, P., Simons, S., Sanchez, E. and Danielsen, M. The Nuclear Receptor Resource: a growing family (1998), Nucleic Acids Res 26:239-241.  PMID: 9471621.

Martinez, E., Moore, D., Keller, E. Pearce, D., Robinson, V., McDonald, P., Simons, S., Sanchez, E., Danielsen, M. The Nuclear Receptor Resource Project (1997), Nucleic Acids Res 25:163-165. PMID: 9016529.

Danielsen, M. and Martinez, E. The glucocorticoid receptor resource (1996), Nucleic Acids Res 24:155-156. PMID: 8594567.