Featured Publications

eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons.

Yang Q, Yu CH, Zhao F, Dang Y, Wu C, Xie P, Sachs MS, Liu Y, Nucleic Acids Res. 2019 Aug

Codon usage biases co-evolve with transcription termination machinery to suppress premature cleavage and polyadenylation.

Zhou Z, Dang Y, Zhou M, Yuan H, Liu Y Elife 2018 Mar 7

DNA Replication Is Required for Circadian Clock Function by Regulating Rhythmic Nucleosome Composition.

Liu X, Dang Y, Matsu-Ura T, He Y, He Q, Hong CI, Liu Y Mol. Cell 2017 Jun

Codon usage regulates protein structure and function by affecting translation elongation speed in Drosophila cells.

Zhao F, Yu CH, Liu Y Nucleic Acids Res. 2017 Jun

Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing.

Dang Y, Cheng J, Sun X, Zhou Z, Liu Y Genes Dev. 2016 Nov 30 21 2417-2432

Codon usage is an important determinant of gene expression levels largely through its effects on transcription.

Zhou Z, Dang Y, Zhou M, Li L, Yu CH, Fu J, Chen S, Liu Y Proc. Natl. Acad. Sci. U.S.A. 2016 Sep

Codon usage affects the structure and function of the Drosophila circadian clock protein PERIOD.

Fu J, Murphy KA, Zhou M, Li YH, Lam VH, Tabuloc CA, Chiu JC, Liu Y Genes Dev. 2016 Aug 30 15 1761-75

Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding.

Yu CH, Dang Y, Zhou Z, Wu C, Zhao F, Sachs MS, Liu Y Mol. Cell 2015 Aug

Mechanism of siRNA production from repetitive DNA.

Yang Q, Ye QA, Liu Y Genes Dev. 2015 Feb

Transcriptional interference by antisense RNA is required for circadian clock function.

Xue Z, Ye Q, Anson SR, Yang J, Xiao G, Kowbel D, Glass NL, Crosthwaite SK, Liu Y Nature 2014 Aug