Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
Chen S, Jiao L, Shubbar M, Yang X, Liu X Mol. Cell 2018 Mar 69 5 840-852.e5
Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2.
Long Y, Bolanos B, Gong L, Liu W, Goodrich KJ, Yang X, Chen S, Gooding AR, Maegley KA, Gajiwala KS, Brooun A, Cech TR, Liu X Elife 2017 Nov 6
Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2.
Jiao L, Liu X Science 2015 Oct 350 6258 aac4383
Initiation complex structure and promoter proofreading.
Liu X, Bushnell DA, Silva DA, Huang X, Kornberg RD Science 2011 Jul 333 6042 633-7
Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.
Liu X, Bushnell DA, Wang D, Calero G, Kornberg RD Science 2010 Jan 327 5962 206-9
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.
Liu X, Wang L, Zhao K, Thompson PR, Hwang Y, Marmorstein R, Cole PA Nature 2008 Feb 451 7180 846-50
Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor.
Liu X, Marmorstein R Genes Dev. 2007 Nov 21 21 2711-6
Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator crosstalk.
Bratkowski M, Unarta IC, Zhu L, Shubbar M, Huang X, Liu X J. Biol. Chem. 2017 Nov
Polycomb repressive complex 2 in an autoinhibited state.
Bratkowski M, Yang X, Liu X J. Biol. Chem. 2017 08 292 32 13323-13332
Structural analysis of an active fungal PRC2.
Jiao L, Liu X Nucleus 2016 May 0