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Histone mark H3K36me3 recruits MutSα to replicating chromatin

Cell 153, 590-600. Lead author: Feng Li

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Reconstitution of human mismatch repair in a defined system

Cell 122, 693-705. Lead authors: Yanbin Zhang and Fenghua Yuan

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dMMR facilitates immunotherapy by activating immune signaling

Cancer Cell 39, 109-121. Lead author: Junhong Guan

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Mechanism of mismatch repair

Cell Res. Lead authors: Janice Ortega and Grace Lee

Research

We are broadly interested in cellular mechanisms maintaining genome stability and their impact on human diseases, including cancer and neurodegenerative disorders. Learn more

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Publications

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