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Histone mark H3K36me3 recruits MutSα to replicating chromatin

Cell 153, 590-600. Lead author: Feng Li

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Reconstitution of human mismatch repair in a defined system

Cell 122, 693-705. Lead authors: Yanbin Zhang and Fenghua Yuan

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MutSβ promotes trinucleotide repeat expansion

Cell Res 26, 775-786. Lead author: Jinzhen Guo

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Phosphorylated PCNA promotes a mutator phenotype

PNAS 112, 5667-5672. Lead author: Janice Ortega

Research

We are broadly interested in cellular mechanisms maintaining genome stability and their impact on human diseases, including cancer and neurodegenerative disorders. Learn more

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Publications

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