Sridevi Challa, Ph.D. • Postdoctoral Fellow

Sridevi Challa

I am interested in understanding the molecular crosstalk between metabolites and signaling pathways in cancer. Utilizing various cell biology and biochemical tools developed by the Kraus lab, I am deciphering the cytosolic processes commonly regulated by enzymes in NAD+ biosynthesis pathways and PARPs in ovarian cancer.


Ryu, K. W., Nandu, T., Kim, J., Challa, S., DeBerardinis, R. J., Kraus, W. L. (2018) Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. Science, 6289 (360), doi:10.1126/science.aan5780

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