People

Sridevi Challa, Ph.D. • Postdoctoral Fellow

Sridevi Challa

I am interested in understanding the molecular crosstalk between metabolites and signaling pathways in cancer. Utilizing various cell biology and biochemical tools developed by the Kraus lab, I am deciphering the cytosolic processes commonly regulated by enzymes in NAD+ biosynthesis pathways and PARPs in ovarian cancer.

Publications

Ryu, K. W., Nandu, T., Kim, J., Challa, S., DeBerardinis, R. J., Kraus, W. L. (2018) Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. Science, 6289 (360), doi:10.1126/science.aan5780

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