People

People

Group lunch, July 2019



Khuloud Jaqaman, Ph.D.

Khuloud Jaqaman, Ph.D.

Principal Investigator
khuloud.jaqaman@utsouthwestern.edu

Khuloud joined the Department of Biophysics at UT Southwestern Medical Center in January 2013 and is excited about pursuing her research program and contributing to the education and training of students and postdocs.

Khuloud received her Ph.D. from Indiana University Bloomington, where she did research in molecular dynamics and protein folding. She then did her postdoctoral studies with Gaudenz Danuser at the Scripps Research Institute, where she got immersed in the fascinating world of investigating receptor dynamics and function in living cells.

Before coming to UTSW, she was an Instructor in the Department of Systems Biology at Harvard Medical School. 


Bruno da Rocha Azevedo, Ph.D.

Bruno da Rocha Azevedo, Ph.D.

Lab director
bruno.darocha-azevedo@utsouthwestern.edu

Bruno is interested in how cells interact with the extracellular environment, and now in the Jaqaman lab he wants to take his studies to the single-molecule scale. For his Ph.D., Bruno studied the interaction between pathogens and the mammalian host. During his postdoctoral trainings at Virginia Commonwealth University and UT Southwestern, and as a Young Talent Research Fellow at Federal University of Rio de Janeiro, he then studied the interaction between mammalian cells and 3D extracellular matrices.

Bruno is the director of the experimental branch of the lab, mentoring and collaborating with students and fellows in order to obtain amazing data! His research project is focused on the link between the dynamics, interactions and signaling of VEGFR2 on the endothelial cell surface.


Tra Ngo

Tra Ngo

Graduate student
tra.ngo@utsouthwestern.edu

Tra is a graduate student in the Genetics, Development and Disease program, with emphasis in the Mechanisms of Disease and Computational and Systems Biology tracks. She received her bachelor's degree in Molecular Biology and Mathematics from UT Dallas, Richardson, Texas.

In the Jaqaman lab, Tra employs computational and experimental approaches to study the regulation of endothelial cell surface receptor behavior and angiogenic signaling by the cytoskeleton.


Jesus Vega-Lugo

Jesus Vega-Lugo

Graduate student
jesus.vega-lugo@utsouthwestern.edu

Jesus is a graduate student in the Molecular Biophysics program, with emphasis in the Computational and Systems Biology track. He received his bachelor's degree in Mathematics from Universidad del Sagrado Corazon, Puerto Rico, while doing research at the University of Puerto Rico Medical Sciences Campus, where he investigated the molecular mechanisms of mitochondrial dysfunction in heart disease.

In the Jaqaman lab, he is interested in developing computational analysis approaches to quantitatively assess the interactions of membrane receptors with each other, with scaffolding proteins, and with downstream effectors. 


Xian Cheng, Ph.D.

Xian Cheng, Ph.D.

Postdoctoral fellow
xian.cheng@utsouthwestern.edu

Xian received her PhD in Biophysics from the University of Wisconsin-Madison, where she worked in Prof. Tom Record's lab on thermodynamic methods to study individual atom-atom preferential interactions of amides, salts and nucleic acids in water, which can be used to predict/interpret atom-atom contacts in protein assembly, and protein-ligand and protein-nucleic acid complexes among other things.

In the Jaqaman lab, she is interested in learning quantitative microscopy techniques to study the interactions between receptors and downstream effectors.


Aparajita Dasgupta, Ph.D.

Aparajita Dasgupta, Ph.D.

Postdoctoral fellow
aparajita.dasgupta@utsouthwestern.edu

Aparajita received her PhD in Biotechnology from the National Centre for Cell Science (affiliated with Pune university, S.P.P.U), India, where she studied the effect of a novel triterpenoid AECHL-1 on tumor angiogenesis and metastasis. She learned that AECHL-1 could inhibit neo-vessel formation and stall metastasis and EMT by perturbing the cell’s cytoskeleton. Thus, her interest was piqued by the influence that cytoskeletal dynamics can wield on cellular morphology, behavior and survival.

In the Jaqaman lab, she is engaged in studying the regulation of cell surface receptor mobility and signaling by the underlying actin cytoskeleton, using several high resolution and quantitative imaging techniques.


Luciana De Oliveira, Ph.D.

Luciana De Oliveira, Ph.D.

Postdoctoral fellow
luciana.deoliveira@utsouthwestern.edu

Luciana received her B.Sc. and master’s degrees in physics from the University of Santa Maria and a PhD in physics from the University of Bologna. In Santa Maria she worked with numerical modeling of superhydrophobic systems and the construction of phylogenetic trees using random walks and fractal geometry. During her PhD and a previous post-doctoral experience she worked on the stochastic description of biological systems with the master equation and nonequilibrium thermodynamics.

In the Jaqaman Lab, Luciana is developing a stochastic mathematical modeling framework to derive inter-receptor interaction kinetics from the subset of interaction events observed by live-cell single-molecule imaging.


Tieqiao (Tim) Zhang, Ph.D.

Tieqiao (Tim) Zhang, Ph.D.

Microscope manager
tieqiao.zhang@utsouthwestern.edu

Tim received his Ph. D in physics from Peking University, Beijing. China. He has worked in the fields of ultra-fast time resolved laser spectroscopy, optical microscopy and imaging. In the past decade, he focused his research on super-resolution optical microscopy and novel technologies for live cellular imaging.

Tim divides his time between the Jaqaman, Rosen, Yu and Rice labs. In the Jaqaman Lab, he keeps our microscope in best shape and collaborates with other lab members to utilize optical microscopy to study single molecule events. 


Mark Kittisopikul, Ph.D.

Mark Kittisopikul, Ph.D.

Visiting postdoctoral fellow
mark.kittisopikul@utsouthwestern.edu

Mark received his B.S. in Biological Chemistry and Mathematics from the University of Chicago working in the labs of Professors Ka Yee C. Lee and Aaron Dinner where he was initially introduced to the intricacies of the cell membrane. He earned his Ph.D. from UT Southwestern in the lab of Gurol Suel from the Molecular Biophysics program with an emphasis in Computational and Systems Biology. There he studied the dynamics of bacteria as single cells, in host-pathogen interactions, and in biofilm communities through image analysis and simulation.

Mark is currently in the Goldman lab at Northwestern University, studying the relationship between the function and distribution of nuclear lamins using quantitative structured illumination microscopy. He works closely with the Jaqaman lab on the development of novel algorithms to filter and segment intersecting curvilinear structures in microscopy images.



Lab Alumni

 

Was ...

Currently is ...

Anthony Vega

Graduate student, Molecular Biophysics (2014-2018)

Postdoctoral fellow, Diamond and Rajaram labs, UT Southwestern

Deryl Tschoerner

Green fellow/Summer undergraduate research fellow (2018)

Undergraduate student, UT Dallas

Albert Zhang

Summer intern (2018)

Undergraduate student, Emory University

Colton Alstatt

Independent Study (Frisco High School; 2018)

Undergraduate student, Rice University

Mark Kittisopikul, Ph.D.

Postdoctoral fellow (2014-2017)

Postdoctoral fellow, Goldman lab, Northwestern University

Sungsoo Lee, Ph.D.

Lab director (2013-2016)

Research assistant professor, Korea University

Magdalena Woszczek

Exchange student (Poland; 2015-2016)

 

Lauren Baron

STARS summer intern (2015)

Summer intern (2016)

Undergraduate student, University of Pennsylvania

Robel Yirdaw, Ph.D.

Postdoctoral fellow (2013-2014)

Software programmer, University of North Texas