Publications for Dr. Peter Douglas

Featured Publications Legend

Featured Publications

Simultaneous Control of Endogenous and User-Defined Genetic Pathways Using Unique ecDHFR Pharmacological Chaperones.

Ramadurgum P, Woodard DR, Daniel S, Peng H, Mallipeddi PL, Niederstrasser H, Mihelakis M, Chau VQ, Douglas PM, Posner BA, Hulleman JD, Cell Chem Biol 2020 Mar

Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan.

Wang C, Niederstrasser H, Douglas PM, Lin R, Jaramillo J, Li Y, Olswald NW, Zhou A, McMillan EA, Mendiratta S, Wang Z, Zhao T, Lin Z, Luo M, Huang G, Brekken RA, Posner BA, MacMillan JB, Gao J, White MA Nat Commun 2017 Dec 8 1 2270

The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans.

Das R, Melo JA, Thondamal M, Morton EA, Cornwell AB, Crick B, Kim JH, Swartz EW, Lamitina T, Douglas PM, Samuelson AV PLoS Genet. 2017 Oct 13 10 e1007038

The Stress Response Paradox: Fighting Degeneration at the Cost of Cancer.

Arneaud SL, Douglas PM FEBS J. 2016 May

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