Interspecies Interaction and Cell Fates

We have made considerable progress in understanding how individual identical cells react to precise perturbations using various single-cell techniques. But no microorganism in nature exists in isolation; rather, they live in microbial communities where interactions between species are crucial for their fitness and function.

Despite the importance of interspecies relationships, very little is known about how these interactions shape cell fates in real time at the single-cell level. As a starting point, we will study interspecies relations using host-pathogen interactions between fungi and immune cells.

Diagram of cell growth
Yeast cells exhibit different fates after phagocytosis.