Investigative Pathology Faculty

Our diverse faculty members share a common goal of probing fundamental mechanisms of disease through basic and applied investigations. Dominant themes of research include cancer biology and immunology, with expertise in aging, DNA repair, developmental and reproductive biology, bioinformatics, and signal transduction. Labs are staffed by accomplished graduate and medical students, postdoctoral scholars, technical personnel, and physicians.

Highlights of our Investigative Pathology area include:

  • Ties between the labs are strengthened by an annual retreat, as well as bimonthly seminars including the departmental seminar series and a pathophysiology of disease seminar given by pathology residents
  • Wide array of departmental core facilities including molecular histology and flow cytometry

Numerous opportunities exist for collaborations aimed at maximizing the interactions between basic scientists and physicians in the elucidation of mechanisms of disease. We invite you to explore the individual web pages of our investigative faculty.

Dr. James Malter

James S. Malter, M.D.

Dr. Esra Akbay

Esra Akbay, Ph.D.

Dr. Dennis K. Burns

Dennis K. Burns, M.D.

  • Professor
  • Research Interests: Neuromuscular pathology, electron microscopy, and the evaluation of phenotypic alterations in genetically engineered mouse models.
Dr. Kelley Carrick

Kelley Carrick, M.D.

  • Professor
  • Research Interests: Gynecologic pathology
Dr. Diego Castrillon

Diego Castrillon, M.D., Ph.D.

  • Associate Professor
  • Director of Investigative Pathology
  • Research Interests: Understanding the molecular basis of reproduction and diseases of the reproductive tract, with an emphasis on the stem cells that drive these processes.
  • Castrillon Lab
Weina Chen, M.D., Ph.D.

Weina Chen, M.D., Ph.D.

  • Associate Professor
    Director of Hematopathology
  • Co-Director of Flow Cytometry
  • Medical Director, Hematology and Bone Marrow Laboratory
  • Research Interests: Hematopathology, pathobiology of myeloid and lymphoid neoplasms, and flow cytometry.
Dr. Ileana Cuevas

Ileana Cuevas, Ph.D.

Yang-Xin Fu, M.D., Ph.D.

Yang-Xin Fu, M.D., Ph.D.

  • Professor
  • Research Interests: IR-mediated immunity and tumor regression, Lymphotoxin biology and gut Immunity, Next generation antibody-based molecules, Tumor immunology
  • Yang-Xin Fu Lab
Dr. Rene Galindo

Rene Galindo, M.D., Ph.D.

  • Associate Professor
  • Associate Dean of Medical Student Research
  • Research Interests: Genetic and molecular underpinnings of childhood cancer. To address these issues, we are presently utilizing multiple animal model systems (including invertebrate and mammalian models) to dissect the biology of the most common soft-tissue sarcoma of childhood – the skeletal muscle-type tumor rhabdomyosarcoma.
  • Galindo Lab
Dr. Adi Gazdar

Adi Gazdar, M.D.

  • Professor
  • Research Interests: Long term goals of Dr. Gazdar’s research efforts are to determine the molecular and genetic basis of human cancers, and to develop molecular insights to provide prognostic and diagnostic therapies in the treatment of human cancers.
  • Gazdar Lab
Dr. Robert M. Genta

Robert M. Genta, M.D.

  • Clinical Professor
  • Research Interests: Gastritis (Helicobacter pylori) and its associations, eosinophilic esophagitis and patho-epidemiologic studies based on analyses from large databases.
Dr. Ibrahim A. Hashim

Ibrahim A. Hashim, M.Sc., Ph.D.

  • Professor
  • Chief of Clinical Pathology
  • Director of Clinical Chemistry
  • Research Interests: Elucidating the role of inflammatory cytokines and their mediators in the pathogenesis of heatstroke, trauma, and meningitis. I am also interested in proteomics and molecular heterogeneity of prolactin and of cytokines and on posttranslational modifications affecting their biological and immunological activities.
Dr. Kimmo Hatanpaa

Kimmo Hatanpaa, M.D., Ph.D.

  • Associate Professor
  • Research Interests: Brain tumors and neuropathology.
Dr. Rita Holloway

Rita Holloway, Ph.D. ABMM

  • Professor
  • Research Interests: Evaluation of new diagnostic tests in clinical microbiology.
Dr. Sarah Johnson-Welch

Sarah Johnson-Welch, M.D.

  • Professor
  • Director of Autopsy, Children’s Health℠
  • Research Interests: Perinatal and placental pathology and autopsy pathology.
Dr. Patricia Jones

Patricia Jones, Ph.D.

  • Professor
  • Director of Chemistry, Children’s Health℠
  • Research Interests: Inborn errors of metabolism, especially disorders of fatty acid metabolism.
Dr. Payal Kapur

Payal Kapur, M.D.

  • Associate Professor
  • Medical Director Surgical Pathology, Parkland Memorial Hospital
  • Group Leader, Genitourinary Pathology, UTSW
  • Kidney Cancer Program Co-Leader, Simmons Cancer Center
  • Research Interests: Adult genitourinary pathology.
Dr. Weibo Luo width=

Weibo Luo, Ph.D.

  • Assistant Professor
  • Pathology, Pharmacology
  • Graduate Programs: Cancer Biology
  • Research Interests:• Epigenetics • Gene regulation • Hypoxia • Hypoxia-inducible factor • Metabolism • Tumor growth and metastasis
  • Weibo Luo Lab
Dr. Srinivas Malladi

Srinivas Malladi, Ph.D.

  • Assistant Professor
  • Research Interests: Cancer Metastasis, Metastatic stem cells, Tumor biology and microenvironment
  • Malladi Lab
Dr. Ram Mani

Ram Mani, Ph.D.

  • Assistant Professor
  • Mani Lab
  • Research Interests: Epigenetic mechanisms underlying cancer progression, ETS gene fusions in prostate cancer, Genomic rearrangements in cancer, Transcriptional regulation in prostate cancer.
Dr. Kyle Molberg

Kyle Molberg, M.D.

  • Professor
  • Chief of Pathology Services, Parkland Memorial Hospital
  • Research Interests: General surgical pathology and urologic pathology.
Dr. Daniel Noland

Daniel Noland, M.D.

  • Assistant Professor
  • Medical Director of Transfusion and Tissue Service, Children’s Health℠
  • Research Interests: Clinical and translation applications of therapeutic apheresis and pediatric transfusion medicine.
Dr. Dwight Oliver

Dwight Oliver, M.D.

  • Associate Professor
  • Research Interests: Development of molecular diagnostic assays and their applications in oncology and infectious disease.
Dr. Jason Park

Jason Park, M.D., Ph.D.

  • Associate Professor
  • Clinical Director of Advanced Diagnostics, Children’s Health℠
  • Research Interests: Development of clinical laboratory technologies with a focus on gastrointestinal and liver pathology and pediatric diseases.
Dr. Lan Peng

Lan Peng, M.D.

  • Associate Professor
  • Research Interests: Autoimmune hepatitis, acute liver failure, pancreatic neoplasm, inflammatory bowel disease.
Dr. Yan Peng

Yan Peng, M.D., Ph.D.

  • Associate Professor
  • Research Interests: To explore prognostic and predictive tumor biomarkers for breast cancer by immunohistochemistry and molecular techniques.
Dr. Dinesh Rakheja

Dinesh Rakheja M.D.

  • Associate Professor
  • Chief of Pediatric Pathology, Children’s Health℠
  • Research Interests: Pediatric solid tumors
Dr. James Richardson

James Richardson, D.V.M., Ph.D.

  • Professor
  • Director of Sophomore Medical School Course
  • Research Interests: Analysis of murine phenotypes, comparative pathology, and developmental biology.
  • Richardson Lab/Molecular Pathology
Dr. Ravi Sarode

Ravi Sarode, M.D.

  • Professor
  • Chief of Pathology and Medical Director, Clinical Laboratory Services
  • Research Interests: TTP platelet function disorders, HIT, management of anticoagulation related bleeding, thrombophilia, and patient blood management.
Dr. Venetia Sarode

Venetia Sarode, M.D.

  • Professor
  • Research Interests: Related to breast cancer biomarkers and the impact of neoadjuvant chemotherapy on biomarker expression and the biology of HER2-positive breast cancer.
Dr. Zhong-Jian Shen

Zhong-Jian Shen, M.D., Ph.D.

  • Instructor
  • Research Interests: Member of the Malter Lab
Dr. Timothy Sliter

Timothy Sliter, Ph.D.

  • Associate Professor
Dr. Paul Southern

Paul Southern, M.D.

  • Professor
  • Director of Microbiology, Parkland Memorial Hospital
  • Research Interests: Define the prevalence of infection due to Trypanosoma cruzi (Chagas disease) in the human population of the Toledo District of Belize.
  • Southern Lab
Dr. Jose Torrealba

Jose Torrealba, M.D.

  • Associate Professor
  • Associate Director of Anatomic Pathology
  • Medical Director of Histology, IHC Laboratories, and Renal Pathology
  • Director of General Surgical Pathology – Zale Lipshy University Hospital
  • Research Interests: Immunopathology of solid organ transplantation; mechanisms involved in the development of chronic allograft injury, including alloimmunity, autoimmunity, and non-immune related allograft injury.
Dr. Yingfei Wang

Yingfei Wang, Ph.D.

  • Assistant Professor
  • Pathology, Neurology & Neurotherapeutics
  • Research Interests: • Cell Death/Cell Survival • DNA Damage • Epigenetics • Nuclease • Stroke/Acute brain injury
  • Yingfei Wang Lab
Dr. Charles White III

Charles White III, M.D.

  • Professor
  • Director of Neuropathology 
  • Research Interests: Alzheimer disease, Digital and quantitative neuropathology, Forensic neuropathology, Immunohistochemistry, Neurodegenerative disorders, and Tissue microarray technology
Dr. Hasan Zaki

Hasan Zaki, Ph.D.

  • Assistant Professor
  • Research Interests: NOD-like receptors, host-pathogen interaction, inflammatory bowel disease, and colorectal cancer
  • Zaki Lab
Dr. Wenxin Zheng

Wenxin Zheng, M.D.

  • Professor
  • Research Interests:
    • Biomarkers to aid the diagnosis of gynecologic cancers
    • Cervical cancer: suitable model of cervical cancer screening, effective intervention, and prevention in developing countries.
    • Endometrial serous carcinoma: carcinogenesis, early detection and prevention
    • Ovarian cancer early detection and prevention
    • Tubal origin of ovarian endometriosis and its related cancer development
    • Tubal secretory cell biology
  • Zheng Lab