Neuropathology Rotation

The Neuropathology rotation is required for all AP and AP/CP residents at UT Southwestern Medical Center. Recognizing the specialized nature of the diagnostic studies carried out in Neuropathology, it is a senior resident-level rotation. Residents on the Neuropathology rotation divide their time among:

Under the supervision of the Neuropathology faculty, residents work with Neuropathology fellows as they actively participate in the evaluation of a comprehensive body of pathological lesions of the central nervous system, peripheral nervous system, and neuromuscular systems. Residents evaluate representative brain biopsies, autopsy brain cases, neuromuscular biopsies, and outside consultation cases submitted to Neuropathology during the time that they are assigned to the rotation. Cases are first evaluated independently by the resident, and then reviewed for sign out with Neuropathology attending staff.

Clinical Case Material

Neuropathology has an extensive archival collection of clinical case material that consists of more than 200,000 microscopic slides, 16,000 electron micrographs, 10,000 gross and microscopic Kodachromes or digital photographs, 500 fixed museum specimens, and 45 plastic embedded brain slices that represent more than 37,000 cases collected since 1972. All of this material as well as the respective diagnostic reports, other relevant clinical information, and selected radiographs are filed within Neuropathology. It is immediately accessible for study and retrievable through a computerized indexing system. Every major neurologic disease category is represented in this material, including:

  • Degenerative
  • Infectious
  • Neoplastic
  • Infectious/Inflammatory
  • Demyelinating
  • Metabolic
  • Congenital/Malformative
  • Vascular
  • Traumatic disorders
  • Neuromuscular disease and many examples of normal tissues


Residents participate actively in regular conferences, including regular attendance, background preparation for case reviews, and participation in discussions. Many of these conferences are interdisciplinary activities that involve other clinical neuroscience departments. The Departments of Pathology, Neurology, Neurological Surgery, and Psychiatry, the Eugene McDermott Center for Human Growth and Development, the Alzheimer’s Disease Center, and the institution sponsor a variety of regular seminars, guest speakers, and other educational programs that are available to residents on the Neuropathology rotation.


One month



Prior rotations in autopsy and surgical pathology.



  • Alzheimer’s Disease Center CPC (approximately monthly)
  • Forensic Brain Cutting Conference (weekly)
  • Forensic Neuropathology Slide Review Conference (weekly)
  • Hospital Brain Cutting Conference (weekly)
  • Neuromuscular Biopsy Review Conference (weekly)
  • Neuro-Oncology Conference/Tumor Board (weekly)
  • Neuropathology Case Review Conference (semi-weekly)
  • Neuropathology Journal Club/Works in Progress Conference (biweekly)
  • Neuropathology Resident Lecture Series (weekly Fall)
  • Pituitary Conference (quarterly)

Basic Reading

  • Escourolle and Poirier's Manual of Basic Neuropathology, 4th Edition, by Gray F, Poirer J, and De Girolami U, (copy available for use in Neuropathology area)

For Reference

  • Neuropathology: A Reference Text of CNS Pathology, 2nd Edition, by Ellison D et al (copy available for use in Neuropathology area)
  • Surgical Pathology of the Nervous System and Its Coverings, 4th Edition, by Burger PC, Scheithauer BW, and Vogel FS