Research Studies

The Alzheimer's Disease Center (ADC) has several studies underway and we are looking for volunteers to help us learn more about memory loss. To volunteer, fill out our Join a Study form or contact the research coordinators listed with each study.

ARTFL – Advancing Research and Treatment for Frontotemporal Lobar Degeneration (FTD): Research Projects 1 & 2

The goal of this study is to collect data from cognitive tests, brain MRI scans, blood tests, and cerebral spinal fluid tests (Lumbar Punctures are optional) to support the development of FTD therapies for new clinical trials. Participants will have their blood tested for the presence of FTD-associated genes; this information will be compared to the neurological and cognitive data that is collected to help design potential new therapies. The ARTFL study is a Registry Study and requires you to have a reliable Study Partner for you to be eligible to participate. It will require two to four visits to our clinic to complete the testing. You may be asked to return in one year to repeat testing. If you are between the ages of 18 and 85, have been diagnosed with FTD, and are interested in participating in this study, please call Jana Windsor at 214-648-9118.

LOAD (Late-Onset Alzheimer’s Disease) Study

This study is being done to help researchers learn more about risk factors which might be associated with the development of diseases of the nervous system associated with late-onset Alzheimer’s disease (late onset is defined as symptoms of AD beginning at age 60 or older), aging, and other related disorders. Other related disorders may include early-onset Alzheimer’s disease, frontotemporal degeneration, Lewy body dementia, corticobasal degeneration, and progressive supranuclear palsy.

Participants will have a neurological examination, a blood draw, and take cognitive (memory and thinking) tests. The LOAD study requires you to have a reliable Study Partner (someone who knows you really well) in order for you to participate. You may be asked to return annually for up to 5 years to repeat the same testing. If you are 50 years and older, have been diagnosed with AD, have at least 1 more family member with dementia, and are interested in participating in this study, please call Amy Browning at 214-645-1972.

rrAD (Risk Reduction for Alzheimer's Disease)

This study is testing several strategies that may reduce the risk of Alzheimer’s disease in individuals who have risk factors for the disease. These strategies include:

  • Aerobic exercise
  • Intensive medical management of blood pressure and cholesterol
  • The combination of these two approaches
  • Standard care

To participate, you must be 60 to 85 years old and have (1) hypertension and (2) a family history of dementia in a first-degree relative (sibling or parent) or concerns about your memory. A total of 640 volunteers will be enrolled in this study and participation will last approximately two years.

For more information or to volunteer, contact:

Tristyn Hall
Call: 214-345-4665