In the News
FDA approves new standard of care for kidney cancer
The U.S. Food and Drug Administration granted approval to the combination of two immunotherapy drugs, ipilimumab and nivolumab, for the treatment of metastatic kidney cancer. “The approval of this combination immunotherapy is the most significant advance for the treatment of kidney cancer over the last 10 years. Not only is this therapy superior than the current the standard of care, but patients experienced also a better quality of life,” said Dr. Hans Hammers, Associate Professor of Internal Medicine and Co-Leader of the Kidney Cancer Program at UT Southwestern. “However, serious side effects can occur which require timely diagnosis and expertise in their management.”
Nijhawan to receive 2018 Seldin-Smith Awar
UT Southwestern’s Dr. Deepak Nijhawan became a co-recipient of the 2018 Donald Seldin-Holly Smith Award for Pioneering Research.
Dr. Jain awarded CPRIT funding for Hep C Screening
The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded UT Southwestern researchers more than $27 million, including nearly $3 million for two key cancer screening programs in underserved areas, lung cancer screenings and Liver Cancer/Hepatitis C screening. Dr. Mamta Jain, Director of the HIV Research Unit at UT Southwestern, will conduct hepatitis C screening among baby boomers, with the goal of reducing the incidence of liver cancer.
The two-part program involves developing a population-based electronic alert at John Peter Smith Hospital and using a mobile van to screen residents in eight North Texas counties. The program aims to screen more than 20,000 patients through combined efforts at JPS and community outreach programming.
UT Southwestern earns accreditation from the ACHD
In recognition of its expertise in serving adults with congenital heart disease (CHD), UT Southwestern Medical Center and Children’s Health℠ have received accreditation from the Adult Congenital Heart Association (ACHA), a nationwide organization focused on connecting patients, family members and health care providers to form a community of support and network of experts with knowledge of congenital heart disease.
Nutrient-deficient diet a key Type 2 diabetes contributor
The new UT Southwestern study showed that U.S. South Asians with Type 2 diabetes consumed fewer calories but also consumed less beneficial nutrients than healthy South Asians.
“This is the first study that thoroughly compared both the macronutrient and micronutrient intakes in South Asians with and without Type 2 diabetes using an objective measure – a three-day dietary assessment method that included images of all foods consumed,” said Dr. Abhimanyu Garg, Professor and senior author of the study in Diabetes Research and Clinical Practice.
Dr. Hobbs receives Harrington Prize
Geneticist Dr. Helen Hobbs is the 2018 recipient of the Harrington Prize for Innovation in Medicine for her discovery of a novel way to reduce cholesterol. Dr. Hobbs, Director of the Eugene McDermott Center for Human Growth and Development, Professor of Internal Medicine and Molecular Genetics, is the fifth recipient of the Harrington Prize and the first woman to be honored.
Touchstone Center investigation into glucagon's role in diabetic heart disease
A UT Southwestern study reveals the hormone glucagon's importance to the development of insulin resistance and cardiac dysfunction during Type 2 diabetes, presenting opportunities to develop new therapies for diabetic diseases of the heart muscle. “This investigation found that inhibiting glucagon action has potent anti-diabetic effects. This treatment reduces the potent negative effects that fats have on tissues,” said Dr. Philipp Scherer, Director of the Touchstone Center and Professor of Internal Medicine and Cell Biology
Dr. Anderson thrilled to be part of CAR-T clinical trial
UT Southwestern Medical Center is one of nine exclusive sites in the country enrolling multiple myeloma patients for a clinical trial of the CAR-T "living drug" therapy for cancer. “It’s thrilling to be part of this pioneering effort using a genetically modified version of the patient’s own T cells to fight their cancer,” said site investigator Dr. Larry Anderson, Associate Professor of Internal Medicine with UT Southwestern’s Simmons Cancer Center.
Dr. Zigman finds ghrelin affects exercise and food intake
The hormone ghrelin and its receptor influence both exercise endurance and food intake following exercise, new research from UT Southwestern indicates. “Circulating ghrelin concentrations increase as an adaptation to counter metabolically and behaviorally stressful environments. Our results suggest that exercise is another condition that raises levels of the hormone,” said Dr. Jeffrey Zigman, senior author of the study.
Liver cancer screening rates must improve
Patients with cirrhosis should be screened regularly for liver cancer, though few are – in part because busy physicians often don’t order the screening tests, said UT Southwestern oncologists.
“The frequency of liver cancer is increasing rapidly in the U.S. and liver cancer-related mortality has nearly doubled over the past decade. The poor prognosis of the disease is largely driven by the failure to diagnose the disease at an early stage,” said Dr. Amit G. Singal, Medical Director of the Liver Tumor Program at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center.