Recent Publications
These publications highlight the work of our faculty (noted in bold text) and our trainees (noted in underlined text).
2020 Publications
2020 Publications
- Arora G., Gupta A., Guo T., Gandhi A., Laine A., Williams D., Ahn C., Iyengar P., and Infante R. JAK Inhibitors Suppress Colon Cancer Cachexia-Associated Anorexia and Adipose Wasting in Mice. JCSM Rapid Commun., Jul-Dec 2020;3(2):115-128.
- A. Aday, J. O’Leary. Acute on Chronic Liver Failure: Definition and Implications. Clin Liver Dis. 2020 Aug;24(3):521-534.
- Ajayi F, Jan J, Singal AG, Rich NE. Racial and sex disparities in hepatocellular carcinoma in the United States. Current Hepatology Reports 2020 (accepted, in press).
- L. Casey, R. Fontana, A. Aday, D. Nelson, J. Rule, M. Gottfried, M. Tran, W. Lee. Acute Liver Failure (ALF) in Pregnancy: How Much Is Pregnancy-Related? Hepatology. 2020 Jan 28;10.1002/hep.31144.
- L. Casey, A. Aday, J. Rule, W. Lee. Response to letter concerning our Pregnancy manuscript. Hepatology. 2020 May 17. PMID: 32418234.
- Chen Y, Lee, JY, Sridhar S, Mittal V, McCallister K, Singal AG. Improving cancer outreach effectiveness through targeting and economic assessments: insights from a randomized field experiment. Journal of Marketing 2020; 84(3): 1-27.
- Chen VL, Singal AG, Tapper EB, Parikh ND. Hepatocellular carcinoma surveillance, early detection and survival in a privately insured US cohort. Liver International 2020; 40(4): 947-55.
- Deja S, Fu X, Fletcher J, Kucejova B, Browning JD, Young J, Burgess SC. Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver. Metab. Eng. 2020; 59:1-14.
- Faqih A, Singal AG, Fullington H, Hewitt B, Burstein E, Gopal P, Wylie A, Abrams J, Murphy CC. Colorectal neoplasia among patients with and without human immunodeficiency virus. Cancer Epi Biomarker Prev 2020; 29(8): 1689-91.
- Gu P, Yang E, Chittajallu P, McNeill C, Singal AG, Kwon J, Ahmed T. Patient perception and clinical impact of direct-to-consumer advertising in inflammatory bowel disease. Dig Dis Sci 2020 Mar 7.
- Hester CA*, Karbhari N*, Rich NE, Augustine M, Mansour JC, Polanco PM, Porembka MR, Wang SC, Zeh HJ, Singal AG‡, Yopp AC‡. Effect of fragmentation of cancer care on treatment use and survival in hepatocellular carcinoma. Cancer 2019; 125(19):3428-3436.
- Hernaez R, Kramer J, Khan A, Phillips J, McCallister K, Chaffin K, Hernandez A, Fullingon H, Ortiz C, Blackwell J, Loewen A, Liu Y, Tiro JA, Lee SC, Singal AG. Prevalence of Depression and Anxiety in a US Cohort of Patients with Cirrhosis. Clinical Gastroenterology Hepatology (in press).
- Higashi R, Jain M, Quirk L, Rich NE, Waljee AK, Turner B, Lee SC, Singal AG. Patient and Provider-Level Barriers to Hepatitis C Screening and Linkage to Care: A Mixed-Methods Evaluation. J Viral Hepatitis 2020; 27(7): 680-89.
- Jackson DN, Alula KM, Delgado-Deida Y, Tabti R, Turner K, Wang X, Venuprasad K, Souza RF, Désaubry L, Theiss AL. The synthetic small molecule FL3 combats intestinal tumorigenesis via Axin1-mediated inhibition of Wnt/beta-catenin signaling. Cancer Res. 2020 Sep 1;80(17):3519-3529.
- Jackson DN, Panopoulos M, Neumann WL, Turner K, Cantarel BL, Thompson-Snipes L, Dassopoulos T, Feagins LA, Souza RF, Mills JC, Blumberg RS, Venuprasad K, Thompson WE, Theiss AL. Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis. Gut. 2020. 2020 Nov;69(11):1928-1938.
- John BV, Aubuchon S, Dahman B, KonjetiVR, Heuman D, Hubert J, Thomas S, Deng Y, Soloman C, Sundaram LT, Love E, Singal AG, Tatum J. Addition of 18F-FDG PET/CT to Cross-Sectional Imaging Improves Staging and Alters Management in Hepatocellular Carcinoma. Liver Transplantation 2020; 26(6): 774-84.
- Kathania M, Tsakem EL, Theiss AL, Venuprasad K. Gut Microbiota Contributes to Spontaneous Colitis in E3 Ligase Itch-Deficient Mice. J Immunol. 2020. 15;204(8):2277-2284.
- Khatri G, Pedrosa I, Ananthakrishnan L, Diaz de Leon A, Fetzer DT, Leyendecker J, Xi Y, Singal AG, Yopp A, Yokoo T. Abbreviated-protocol screening MRI versus complete-protocol diagnostic MRI for detection of hepatocellular carcinoma in patients with cirrhosis – an equivalence study using LI-RADS v2018. Journal of Magnetic Resonance Imaging 2020; 51(2): 415-25.
- Liu PH, Hsu CY, Su CW, Huang YH, Hou MC, Rich NE, Fujiwara N, Hoshida Y, Singal AG, Huo TI. Thrombocytosis is associated with worse survival in patients with hepatocellular carcinoma. Liver International. 2020 Oct;40(10):2522-2534.
- McDevitt JL, Collard M, Sutphin PD, Singal AG, Yopp AC, Kalva SP. Comparison of radiofrequency and microwave ablation and identification of risk factors for primary treatment failure and local progression. Clinical Imaging 2020; 67: 146-151.
- Mukherjee S, Kumar R, Tsakem Lenou E, Basrur V, Kontoyiannis DL, Ioakeimidis F, Mosialos G, Theiss AL, Flavell RA, Venuprasad K. Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation. Nat Immunol. 2020. 21(6):626-635.
- Murphy CC, Halm E, Skinner CS, Balasubramanian B, Singal AG. Challenges and approaches to repeat fecal immunochemical test for colorectal cancer screening. Cancer Epi Biomarker Prev 2020; 29(8): 1557-63.
- Murphy CC, Sen A, Sigel B, Gupta S, Mayo H, Singal AG. A systematic review of repeat fecal occult blood tests for colorectal cancer screening. Cancer Epi Biomarkers Prev 2020; 29(2): 278-87.
- Nathani P, Gopal P, Rich N, Yopp A, Yokoo T, John B, Marrero J, Parikh N, Singal AG. Hepatocellular carcinoma tumor volume doubling time: A systematic review and meta-analysis. Gut 2020 May 12;gutjnl-2020-321040.
- Osho A, Rich NE, Singal AG. Role of imaging in management of hepatocellular carcinoma: surveillance, diagnosis and treatment response. Hepatoma Research 2020;6:55.
- Rich NE, Yopp AC, Murphy CC, Singal AG. Hepatocellular carcinoma Incidence is Decreasing among Younger Adults in the United States. Clinical Gastroenterology Hepatology 2020; 18(1) 242-248.
- Rich NE, Yang JD, Perumalswami P, Alkhouri N, Jackson W, Parikh ND, Mehta N, Salgia R, Duarte-Rojo A, Kulik L, Rakoski M, Said A, Oloruntoba O, Ioannou G, Hoteit M, Moon AM, Rangnekar AS, Eswaran S, Zheng E, Jou J, Hanje J, Pillai A, Hernaez R, Wong R, Scaglione S, Samant H, Kapuria D, Chanda S, Rosenblatt R, Ajmera V, Frenette C, Sataphathy S, Mantry P, Jalal P, John B, Fix O, Leise M, Lindenmayer C, Flores A, Patel N, Jiang ZG, Latt N, Dhanasekharan R, Odewole M, Kagan S, Marrero J, Singal AG. Provider attitudes and practice patterns for direct-acting antiviral therapy for patients with hepatocellular carcinoma. Clinical Gastroenterology Hepatology 2020; 18(4): 974-83.
- Rich NE, Murphy CC, Yopp AC, Tiro J, Marrero JA, Singal AG. Sex Disparities in Presentation and Prognosis of Patients with Hepatocellular Carcinoma. Alimentary Pharmacology and Therapeutics 2020; 52(4): 701-709.
- Rich NE, John BV, Parikh, ND, Rowe I, Mehta N, Khatri G, Thomas SM, Anis M, Mendiratta-Lala M, Hernandez C, Odewole M, Sundaram LT, Konjeti VR, Shetty S, Shah T, Zhu H, Yopp A, Hoshida Y, Yao FY, Marrero JA, Singal AG. Hepatocellular carcinoma demonstrates heterogeneous growth patterns in a multi-center cohort of patients with cirrhosis. Hepatology 2020 Nov;72(5):1654-1665.
- Scaglione S, Adams W, Caines A, Devlin P, Mittal S, Parikh N, Singal AG. Association between race/ethnicity and insurance status with outcomes in patients with hepatocellular carcinoma. Digestive Diseases and Sciences 2020; 65(6): 1669-78.
- Singal AG, Parikh ND, Hutton DW, Tapper EB. Cost effectiveness of hepatocellular carcinoma surveillance: An assessment of benefits and harms. Am J Gastro 2020 Oct;115(10):1642-1649.
- Singal AG, Tiro JA, Murphy CC, Blackwell J, Kramer KR, Khan A, Liu Y, Zhang S, Phillips J, Hernaez R. Patient-reported barriers are associated with receipt of hepatocellular carcinoma surveillance in a multi-center cohort of patients with cirrhosis. Clinical Gastroenterology Hepatology 2020 Jul 3;S1542-3565(20)30912-5.
- Sumarsono A, Wang J, Xie L, Chiang G, Tielleman T, Messiah S, Singal AG, Mufti A, Chen C, Leveno M. Prognostic value of hypochloremia in critically ill patients with decompensated cirrhosis. Critical Care Medicine 2020 Nov;48(11):e1054-e1061.
- Tavakkoli A, Elmunzer BJ, Waljee AK, Murphy CC, Pruitt SL, Zhu H, Rong R, Kwon RS, Scheiman J, Rubenstein JH, Singal AG. Survival Analysis Among Unresectable Pancreatic Adenocarcinoma Patients Undergoing Endoscopic or Percutaneous Interventions. Gastrointestinal Endoscopy 2020 Jun 9;S0016-5107(20)34418-7.
- Tavakkoli A, Singal AG, Waljee AK, Elmunzer BJ, Pruitt SL, McKey R, Rubenstein J, Scheiman JM, Murphy CC. Racial Disparities and Trends in Pancreatic Cancer Incidence and Mortality in the United States. Clinical Gastroenterology Hepatology 2020; 18(1): 171-8.
- Tincopa M, Kenney B, Tapper EB, Sharma P, Rogal S, Mellinger J, Saini S, Nallamothu B, Waljee AK, Singal AG. Prescription opioid use is common and associated with worse clinical outcomes in individuals with chronic liver disease. GastroHep 2020; 2(1): 13-21.
- Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis. Cell Metab. 2020 May 5;31(5):969-986.e7.
- Wolf E, Rich NE, Marrero JA, Parikh ND, Singal AG. Utilization of hepatocellular carcinoma surveillance in patients with cirrhosis: A systematic review and meta-analysis. Hepatology 2020 May 8;10.1002/hep.31309.
- Wolf E, Rich NE, Marrero JA, Parikh ND, Singal AG. Utilization of hepatocellular carcinoma surveillance in patients with cirrhosis: A systematic review and meta-analysis. Hepatology (in press).
- Yang JD, Luu M, Singal AG, Noureddin M, Kuo A, Ayoub WS, Sundaram V, Kotler H, Kim I, Todo T, Voidonikolas G, Brennan T, Kosari K, Klein A, Hendifar A, Lu S, Nissen N, Gong J. Detection and Survival of T1 Hepatocellular Carcinoma in the United States. J National Comprehensive Cancer Network 2020 Sep;18(9):1210-1220.
- Yokoo T, Singal AG, Diaz de Leon A, Ananthakrishnan L, Fetzer DT, Pedrosa I, Khatri G. Prevalence and clinical impact of discordant liver observation LI-RADS reporting among abdominal radiologists on multiphase contrast-enhanced MRI in patients with cirrhosis. Abdominal radiology 2020; 45(1): 177-87.
- Zhu M, Li L, Lu T, Yoo H, Zhu J, Gopal P, Wang SC, Porembka MR, Rich NE, Kagan S, Odewole M, Renteria V, Waljee AK, Wang T, Singal AG, Yopp AC, Zhu H. Uncovering biological factors that regulate hepatocellular carcinoma growth using patient derived xenograft assays. Hepatology 2020 Jan 3;10.1002/hep.31096.
2019 Publications
2019 Publications
- Sifuentes-Dominguez L, Starokadomskyy P, Welch J, Gurram B, Park JY, Koduru P, Burstein E. Mosaic Tetrasomy 9p Associated With Inflammatory Bowel Disease. J Crohns Colitis. 2019 Oct 28;13(11):1474-1478.
- Zhu W, Miyata N, Winter MG, Arenales A, Hughes ER, Spiga L, Kim J, Sifuentes-Dominguez L, Starokadomskyy P, Gopal P, Byndloss MX, Santos RL, Burstein E, Winter SE. Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer. J Exp Med. 2019 Oct 7;216(10):2378-2393.
- Singla A, Fedoseienko A, Giridharan SSP, Overlee BL, Lopez A, Jia D, Song J, Huff-Hardy K, Weisman L, Burstein E, Billadeau DD. Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling. Nat Commun. 2019 Sep 19;10(1):4271.
- Sifuentes-Dominguez LF, Li H, Llano E, Liu Z, Singla A, Patel AS, Kathania M, Khoury A, Norris N, Rios JJ, Starokadomskyy P, Park JY, Gopal P, Liu Q, Tan S, Chan L, Ross T, Harrison S, Venuprasad K, Baker LA, Jia D, Burstein E. SCGN deficiency results in colitis susceptibility. Elife. 2019 Oct 30;8. pii: e49910.
- Starokadomskyy P, Wilton KM, Krzewski K, Lopez A, Sifuentes-Dominguez L, Overlee B, Chen Q, Ray A, Gil-Krzewska A, Peterson M, Kinch LN, Rohena L, Grunebaum E, Zinn AR, Grishin NV, Billadeau DD, Burstein E. NK cell defects in X-linked pigmentary reticulate disorder. JCI Insight. 2019 Nov 1;4(21). pii: 125688.
- Setoodeh S, Liu L, Boukhar SA, Singal AG, Westerhoff M, Waljee AK, Ahmed T, Gopal P. The Clinical Significance of Crohn Disease Activity at Resection Margins. Arch Pathol Lab Med. 2019 Apr;143(4):505-509.
- Samant H, Manatsathit W, Dies D, Shokouh-Amiri H, Zibari G, Boktor M, Alexander JS. Cholestatic liver diseases: An era of emerging therapies. World J Clin Cases. 2019 Jul 6;7(13):1571-1581.
- Roussel J, Pandit S, Jordan P, Boktor M, Knowles K, Dela Cruz N, Samant H. Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature. Case Reports Hepatol. 2019 Jun 9;2019:5326428.
- Ford CL, Wang Y, Morgan K, Boktor M, Jordan P, Castor TP, Alexander JS. Interferon-gamma depresses human intestinal smooth muscle cell contractility: Relevance to inflammatory gut motility disturbances. Life Sci. 2019 Apr 1;222:69-77.
- Boyer CJ, Boktor M, Samant H, White LA, Wang Y, Ballard DH, Huebert RC, Woerner JE, Ghali GE, Alexander JS. 3D Printing for Bio-Synthetic Biliary Stents. Bioengineering (Basel). 2019 Feb 9;6(1). pii: E16.
- Deja S, Fu X, Fletcher JA, Kucejova B, Browning JD, Young JD, Burgess SC. Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver. Metab Eng. 2019 Dec 28. pii: S1096-7176(19)30321-0.
- Fletcher JA, Deja S, Satapati S, Fu X, Burgess SC, Browning JD. Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver. JCI Insight. 2019 Apr 23;5. pii: 127737.
- Cappel DA, Deja S, Duarte JAG, Kucejova B, Iñigo M, Fletcher JA, Fu X, Berglund ED, Liu T, Elmquist JK, Hammer S, Mishra P, Browning JD, Burgess SC. Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver. Cell Metab. 2019 Jun 4;29(6):1291-1305.e8.
- McHenry S, Sharma Y, Tirath A, Tsai R, Mintz A, Fraum TJ, Salter A, Browning JD, Flores AG, Davidson NO, Fowler KJ, Ciorba MA, Deepak P. Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping. Clin Gastroenterol Hepatol. 2019 Dec;17(13):2816-2818.
- Pearlman M, Casey L. Who Should Be Gluten-Free? A Review for the General Practitioner. Med Clin North Am. 2019 Jan;103(1):89-99.
- Angiolillo DJ, Bhatt DL, Lanza F, Cryer B, Dong JF, Jeske W, Zimmerman RR, von Chong E, Prats J, Deliargyris EN, Marathi U. Pharmacokinetic/pharmacodynamics assessment of a novel, pharmaceutical lipid-aspirin complex: results of a randomized, crossover, bioequivalence study. J Thromb Thrombolysis. 2019 Nov;48(4):554-562.
- Nguyen AD, Spechler SJ, Shuler MN, Souza RF, Dunbar KB. Unique Clinical Features of Los Angeles Grade D Esophagitis Suggest That Factors Other Than Gastroesophageal Reflux Contribute to its Pathogenesis. J Clin Gastroenterol. 2019 Jan;53(1):9-14.
- Dunbar KB. Gastroenterology for the Internist. Med Clin North Am. 2019 Jan;103(1):xvii-xviii.
- Snyder P, Dunbar K, Cipher DJ, Souza RF, Spechler SJ, Konda VJA. Aberrant p53 Immunostaining in Barrett's Esophagus Predicts Neoplastic Progression: Systematic Review and Meta-Analyses. Dig Dis Sci. 2019 May;64(5):1089-1097.
- Feagins LA, Smith AD, Kim D, Halai A, Duttala S, Chebaa B, Lunsford T, Vizuete J, Mara M, Mascarenhas R, Meghani R, Kundrotas L, Dunbar KB, Cipher DJ, Harford WV, Spechler SJ. Efficacy of Prophylactic Hemoclips in Prevention of Delayed Post-Polypectomy Bleeding in Patients With Large Colonic Polyps. Gastroenterology. 2019 Oct;157(4):967-976.e1.
- Spechler SJ, Hunter JG, Jones KM, Lee R, Smith BR, Mashimo H, Sanchez VM, Dunbar KB, Pham TH, Murthy UK, Kim T, Jackson CS, Wallen JM, von Rosenvinge EC, Pearl JP, Laine L, Kim AW, Kaz AM, Tatum RP, Gellad ZF, Lagoo-Deenadayalan S, Rubenstein JH, Ghaferi AA, Lo WK, Fernando RS, Chan BS, Paski SC, Provenzale D, Castell DO, Lieberman D, Souza RF, Chey WD, Warren SR, Davis-Karim A, Melton SD, Genta RM, Serpi T, Biswas K, Huang GD. Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn. N Engl J Med. 2019 Oct 17;381(16):1513-1523.
- Fudman DI, Roemi L, Leffler DA, Feuerstein JD. High Rate of Incomplete Consent for Colonoscopy: Identifying an Area for Improvement in Gastrointestinal Endoscopy. Am J Med Qual. 2019 Aug 18:1062860619868296.
- Fudman DI, Sattler L, Feuerstein JD. Inpatient Management of Acute Severe Ulcerative Colitis. J Hosp Med. 2019 Dec 1;14(12):766-773.
- Fudman DI, Falchuk KR, Feuerstein JD. Complication rates of trainee- versus attending-performed upper gastrointestinal endoscopy. Ann Gastroenterol. 2019 May-Jun;32(3):273-277.
- Fudman DI, Papamichael K, Roemi L, Rao V, Falchuk KR, Leffler DA, Feuerstein JD. Effect of Consent and Educational Adjuncts to Consent on Patient Perceptions About Colonoscopy. J Clin Gastroenterol. 2019 Sep;53(8):e316-e321.
- Moraveji S, Pedersen MR, Chandramouli S, Kerr TA, Grant LM. More Than a Rash: Recurrent Hepatocellular Carcinoma After Liver Transplantation. ACG Case Rep J. 2019 Jul 10;6(7):e00107.
- Salhanick M, MacConmara MP, Pedersen MR, Grant L, Hwang CS, Parekh JR. Two-stage liver transplant for ruptured hepatic adenoma: A case report. World J Hepatol. 2019 Feb 27;11(2):242-249.
- Crewe C, Zhu Y, Paschoal VA, Joffin N, Ghaben AL, Gordillo R, Oh DY, Liang G, Horton JD, Scherer PE. SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1. JCI Insight. 2019 Jul 16;5. pii: 129397.
- Horton JD. Intravascular triglyceride lipolysis becomes crystal clear. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1480-1482.
- Yarchoan M, Agarwal P, Villanueva A, Rao S, Dawson L, Karasic T, Llovet J, Finn R, Groopman J, El-Serag H, Monga S, Wang XW, Karin M, Schwartz R, Tanabe K, Roberts L, Gunaratne P, Tsung A, Brown K, Lawrence T, Salem R, Singal A, Kim A, Rabiee A, Resar L, Meyer J, Hoshida Y, He AR, Ghoshal K, Ryan P, Jaffee E, Guha C, Mishra L, Coleman N, Ahmed M. Correction: Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma. Cancer Res. 2019 Nov 15;79(22):5897.
- Ishikawa G, Fujiwara N, Hirschfield H, Varricchio L, Hoshida Y, Barosi G, Rosti V, Padilla M, Mazzarini M, Friedman SL, Hoffman R, Migliaccio AR. Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia. Exp Hematol. 2019 Nov;79:16-25.e3.
- Yip SH, Fujiwara N, Burke J, Shetler A, Peralta C, Qian T, Hoshida H, Zhu S, Hoshida Y. MPIC: Molecular Prognostic Indicators in Cirrhosis Database for Clinical Context-Specific in Silico Prognostic Biomarker Validation. Front Genet. 2019 Sep 18;10:830.
- Deltenre P, Trépo E, Fujiwara N, Goossens N, Marot A, Dubois M, Spahr L, Henrion J, Moreno C, Hoshida Y. Gene signature-MELD score and alcohol relapse determine long-term prognosis of patients with severe alcoholic hepatitis. Liver Int. 2019 Sep 30.
- Yarchoan M, Agarwal P, Villanueva A, Rao S, Dawson LA, Llovet JM, Finn RS, Groopman JD, El-Serag HB, Monga SP, Wang XW, Karin M, Schwartz RE, Tanabe KK, Roberts LR, Gunaratne PH, Tsung A, Brown KA, Lawrence TS, Salem R, Singal AG, Kim AK, Rabiee A, Resar L, Hoshida Y, He AR, Ghoshal K, Ryan PB, Jaffee EM, Guha C, Mishra L, Coleman CN, Ahmed MM. Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma. Cancer Res. 2019 Sep 1;79(17):4326-4330.
- Enooku K, Nakagawa H, Fujiwara N, Kondo M, Minami T, Hoshida Y, Shibahara J, Tateishi R, Koike K. Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma. Sci Rep. 2019 Jul 23;9(1):10663.
- Qian T, Zhu S, Hoshida Y. Use of big data in drug development for precision medicine: an update. Expert Rev Precis Med Drug Dev. 2019;4(3):189-200.
- Fujiwara N, Singal AG, Hoshida Y. Dose and Duration of Aspirin Use to Reduce Incident Hepatocellular Carcinoma. Hepatology. 2019 Dec;70(6):2216-2217.
- Baumert TF, Hoshida Y. Addressing the Challenges of Hepatitis C Cure and Persistent Risk of Hepatocellular Carcinoma. Viruses. 2019 May 15;11(5). pii: E441.
- Lupberger J, Croonenborghs T, Roca Suarez AA, Van Renne N, Jühling F, Oudot MA, Virzì A, Bandiera S, Jamey C, Meszaros G, Brumaru D, Mukherji A, Durand SC, Heydmann L, Verrier ER, El Saghire H, Hamdane N, Bartenschlager R, Fereshetian S, Ramberger E, Sinha R, Nabian M, Everaert C, Jovanovic M, Mertins P, Carr SA, Chayama K, Dali-Youcef N, Ricci R, Bardeesy NM, Fujiwara N, Gevaert O, Zeisel MB, Hoshida Y, Pochet N, Baumert TF. Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development. Gastroenterology. 2019 Aug;157(2):537-551.e9.
- Fujiwara N, Hoshida Y. Hepatocellular Carcinoma Risk Stratification by Genetic Profiling in Patients with Cirrhosis. Semin Liver Dis. 2019 May;39(2):153-162.
- Marquardt P, Hoshida Y, Singal AG. Aspirin: Does it Have a Role for Chemoprevention of Hepatocellular Carcinoma? Gastroenterology. 2019 Apr;156(5):1530-1531.
- Hamdane N, Jühling F, Crouchet E, El Saghire H, Thumann C, Oudot MA, Bandiera S, Saviano A, Ponsolles C, Roca Suarez AA, Li S, Fujiwara N, Ono A, Davidson I, Bardeesy N, Schmidl C, Bock C, Schuster C, Lupberger J, Habersetzer F, Doffoël M, Piardi T, Sommacale D, Imamura M, Uchida T, Ohdan H, Aikata H, Chayama K, Boldanova T, Pessaux P, Fuchs BC, Hoshida Y, Zeisel MB, Duong FHT, Baumert TF. HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response. Gastroenterology. 2019 Jun;156(8):2313-2329.e7.
- Golob-Schwarzl N, Bettermann K, Mehta AK, Kessler SM, Unterluggauer J, Krassnig S, Kojima K, Chen X, Hoshida Y, Bardeesy NM, Müller H, Svendova V, Schimek MG, Diwoky C, Lipfert A, Mahajan V, Stumptner C, Thüringer A, Fröhlich LF, Stojakovic T, Nilsson KPR, Kolbe T, Rülicke T, Magin TM, Strnad P, Kiemer AK, Moriggl R, Haybaeck J. High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype. Transl Oncol. 2019 Feb;12(2):256-268.
- Li S, Ghoshal S, Sojoodi M, Arora G, Masia R, Erstad DJ, Lanuti M, Hoshida Y, Baumert TF, Tanabe KK, Fuchs BC. Pioglitazone Reduces Hepatocellular Carcinoma Development in Two Rodent Models of Cirrhosis. J Gastrointest Surg. 2019 Jan;23(1):101-111.
- Lally JSV, Ghoshal S, DePeralta DK, Moaven O, Wei L, Masia R, Erstad DJ, Fujiwara N, Leong V, Houde VP, Anagnostopoulos AE, Wang A, Broadfield LA, Ford RJ, Foster RA, Bates J, Sun H, Wang T, Liu H, Ray AS, Saha AK, Greenwood J, Bhat S, Harriman G, Miao W, Rocnik JL, Westlin WF, Muti P, Tsakiridis T, Harwood HJ Jr, Kapeller R, Hoshida Y, Tanabe KK, Steinberg GR, Fuchs BC. Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma. Cell Metab. 2019 Jan 8;29(1):174-182.e5.
- Athuluri-Divakar SK, Hoshida Y. Generic chemoprevention of hepatocellular carcinoma. Ann N Y Acad Sci. 2019 Mar;1440(1):23-35.
- Johnson KA, Endapally S, Vazquez DC, Infante RE, Radhakrishnan A. Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum. J Biol Chem. 2019 Nov 15;294(46):17289-17300.
- Endapally S, Infante RE, Radhakrishnan A. Monitoring and Modulating Intracellular Cholesterol Trafficking Using ALOD4, a Cholesterol-Binding Protein. Methods Mol Biol. 2019;1949:153-163.
- Tavakkoli A, Singal AG, Waljee AK, Scheiman JM, Murphy CC, Pruitt SL, Xuan L, Kwon RS, Law RJ, Elta GH, Wright-Slaughter P, Valley TS, Kubiliun N, Nathan H, Rubenstein JH, Elmunzer BJ. Regional and racial variations in the utilization of endoscopic retrograde cholangiopancreatography among pancreatic cancer patients in the United States. Cancer Med. 2019 Jul;8(7):3420-3427.
- Chandramouli S, Lee WM, Lo J, Toomay S, Tujios S. Prophylactic Transjugular Intrahepatic Portosystemic Shunt Placement for Cirrhosis Management in Pregnancy. Hepatology. 2019 Dec 21.
- Camarata MA, Gottfried M, Rule JA, Ala A, Lee WM, Stravitz RT, Schilsky ML. Outcomes of acute liver injury (ALI) in adults due to Wilson Disease: Is survival without transplant possible? Liver Transpl. 2019 Dec 14.
- Puri P, Lee WM, Fontana RJ, Kim NK, Durkalski V, McGuire BM, Liou I, Pezzia C, Stravitz RT; Acute Liver Failure Study Group. Alcohol consumption is associated with the severity and outcome of acute liver injury/failure. Liver Int. 2019 Dec 10.
- Oaks Z, Jimah J, Grossman CC, Beckford M, Kelly R, Banerjee S, Niland B, Miklossy G, Kuloglu Z, Kansu A, Lee W, Szonyi L, Banki K, Perl A. Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure. J Inherit Metab Dis. 2019 Nov 26.
- Ren Y, Xu Y, Lee WM, Di Bisceglie AM, Fan X. In-depth serum virome analysis in patients with acute liver failure with indeterminate etiology. Arch Virol. 2019 Nov 18.
- Simmons OL, Meinzer C, Rule J, Lee WM; Acute Liver Failure Study Group. Liver Transplantation for Acetaminophen-Induced Acute Liver Failure: Role of Psychiatric Comorbidity in Listing Decisions and Outcomes. Dig Dis Sci. 2019 Nov 2.
- Zhou K, Wahed AS, Cooper S, Di Bisceglie AM, Fontana RJ, Ghany MG, Khalili M, Lok AS, Perrillo R, Lee WM, Lau DTY, Sterling R, Janssen HLA, Terrault NA. Phase Transition Is Infrequent Among North American Adults With e-Antigen-Negative Chronic Hepatitis B and Low-Level Viremia. Am J Gastroenterol. 2019 Nov;114(11):1753-1763.
- Rakela J, Rule J, Ganger D, Lau J, Cunningham J, Dehankar M, Baheti S, Lee WM; Acute Liver Failure Study Group. Whole Exome Sequencing Among 26 Patients With Indeterminate Acute Liver Failure: A Pilot Study. Clin Transl Gastroenterol. 2019 Oct;10(10):e00087.
- Dong V, Sun K, Gottfried M, Cardoso FS, McPhail MJ, Stravitz RT, Lee WM, Karvellas CJ. Significant lung injury and its prognostic significance in acute liver failure: A cohort analysis. Liver Int. 2019 Sep 30.
- Rich NE, Lee WM. Editorial: liver test abnormalities in oncology patients in the age of the checkpoint inhibitors. Aliment Pharmacol Ther. 2019 Oct;50(7):831-832.
- Stravitz RT, Lee WM. Acute liver failure. Lancet. 2019 Sep 7;394(10201):869-881.
- Bajaj JS, Bloom PP, Chung RT, Hassanein TI, Padilla-Martinez M, Kayali Z, Rockey DC, Sasso R, Muthukumar AR, Lee WM, Denney WS, Gavis EA, Anderson C, Blankstein L, Brennan AM, Puurunen MK, Lawitz E. Variability and Lability of Ammonia Levels in Healthy Volunteers and Patients With Cirrhosis: Implications for Trial Design and Clinical Practice. Am J Gastroenterol. 2019 Aug 21.
- Singh S, Hynan LS, Rule JA, Lee WM. Changes in alpha-foetoprotein and Gc-globulin in relation to outcomes in non-acetaminophen acute liver failure. Liver Int. 2019 Dec;39(12):2368-2373.
- Chang KM, Traum D, Park JJ, Ho S, Ojiro K, Wong DK, Wahed AS, Terrault NA, Khalili M, Sterling RK, Janssen HLA, Shuhart MC, Lau DT, Roberts LR, Johnson GS, Kaplan DE, Betts MR, Lee WM, Lok ASF; Hepatitis B Research Network (HBRN). Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B. PLoS Pathog. 2019 Apr 8;15(4):e1007715.
- Slowik V, Borude P, Jaeschke H, Woolbright BL, Lee WM, Apte U; Acute Liver Failure Study Group. Leukocyte cell derived chemotaxin-2 (Lect2) as a predictor of survival in adult acute liver failure. Transl Gastroenterol Hepatol. 2019 Mar 20;4:17.
- Di Bisceglie AM, King WC, Lisker-Melman M, Khalili M, Belle SH, Feld JJ, Ghany MG, Janssen HLA, Lau D, Lee WM, Ling SC, Cooper S, Rosenthal P, Schwarz KB, Sterling RK, Teckman JH, Terrault N; Hepatitis B Research Network (HBRN). Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B. J Viral Hepat. 2019 Jul;26(7):856-865.
- Ajmera V, Huang H, Dao D, Feld JJ, Lau DT, Patel K, Rule JA, Daly M, Lee WM, Chung RT. Host Genetic Variant in CXCL16 May Be Associated With Hepatitis B Virus-Related Acute Liver Failure. Cell Mol Gastroenterol Hepatol. 2019;7(2):477-479.e4.
- Brahmania M, Lombardero M, Hansen BE, Terrault NA, Lok AS, Perrillo RP, Belle SH, Di Bisceglie AM, Feld JJ, Lee WM, Fried MW, Janssen HLA; Hepatitis B Research Network. Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV Infection. Clin Gastroenterol Hepatol. 2019 Nov;17(12):2541-2551.e2.
- Leventhal TM, Gottfried M, Olson JC, Subramanian RM, Hameed B, Lee WM; Acute Liver Failure Study Group. Acetaminophen is Undetectable in Plasma From More Than Half of Patients Believed to Have Acute Liver Failure Due to Overdose. Clin Gastroenterol Hepatol. 2019 Sep;17(10):2110-2116.
- Spivak I, Arora J, Meinzer C, Durkalski-Mauldin V, Lee WM, Trautwein C, Fontana RJ, Strnad P; Acute Liver Failure Study Group (ALFSG). Low Serum Hepcidin Is Associated With Reduced Short-Term Survival in Adults With Acute Liver Failure. Hepatology. 2019 May;69(5):2136-2149.
- Bangaru S, Marrero JA, Singal AG. Review article: new therapeutic interventions for advanced hepatocellular carcinoma. Aliment Pharmacol Ther. 2020 Jan;51(1):78-89.
- Rich NE, Yang JD, Perumalswami PV, Alkhouri N, Jackson W, Parikh ND, Mehta N, Salgia R, Duarte-Rojo A, Kulik L, Rakoski M, Said A, Oloruntoba O, Ioannou GN, Hoteit MA, Moon AM, Rangnekar AS, Eswaran SL, Zheng E, Jou JH, Hanje J, Pillai A, Hernaez R, Wong R, Scaglione S, Samant H, Kapuria D, Chandna S, Rosenblatt R, Ajmera V, Frenette CT, Satapathy SK, Mantry P, Jalal P, John BV, Fix OK, Leise M, Lindenmeyer CC, Flores A, Patel N, Jiang ZG, Latt N, Dhanasekaran R, Odewole M, Kagan S, Marrero JA, Singal AG. Provider Attitudes and Practice Patterns for Direct-Acting Antiviral Therapy for Patients With Hepatocellular Carcinoma. Clin Gastroenterol Hepatol. 2019 Jul 26. pii: S1542-3565(19)30786-4.
- Marrero JA. Obesity and Liver Disease: The New Era of Liver Transplantation. Hepatology. 2019 Aug;70(2):459-461.
- Feng Z, Marrero JA, Khaderi S, Singal AG, Kanwal F, Loo N, Beretta L, Ning J, El-Serag HB. Design of the Texas Hepatocellular Carcinoma Consortium Cohort Study. Am J Gastroenterol. 2019 Mar;114(3):530-532.
- Hemken PM, Sokoll LJ, Yang X, Dai J, Elliott D, Gawel SH, Lucht M, Feng Z, Marrero JA, Srivastava S, Chan DW, Davis GJ. Validation of a novel model for the early detection of hepatocellular carcinoma. Clin Proteomics. 2019 Jan 16;16:2.
- AbdulRahim N, Anderson L, Kotla S, Liu H, Ariyamuthu VK, Ghanta M, MacConmara M, Tujios SR, Mufti A, Mohan S, Marrero JA, Vagefi PA, Tanriover B. Lack of Benefit and Potential Harm of Induction Therapy in Simultaneous Liver-Kidney Transplants. Liver Transpl. 2019 Mar;25(3):411-424.
- Yang JD, Addissie BD, Mara KC, Harmsen WS, Dai J, Zhang N, Wongjarupong N, Ali HM, Ali HA, Hassan FA, Lavu S, Cvinar JL, Giama NH, Moser CD, Miyabe K, Allotey LK, Algeciras-Schimnich A, Theobald JP, Ward MM, Nguyen MH, Befeler AS, Reddy KR, Schwartz M, Harnois DM, Yamada H, Srivastava S, Rinaudo JA, Gores GJ, Feng Z, Marrero JA, Roberts LR. GALAD Score for Hepatocellular Carcinoma Detection in Comparison with Liver Ultrasound and Proposal of GALADUS Score. Cancer Epidemiol Biomarkers Prev. 2019 Mar;28(3):531-538.
- Borges KA, Dai J, Parikh ND, Schwartz M, Nguyen MH, Roberts LR, Befeler AS, Srivastava S, Rinaudo JA, Feng Z, Marrero JA, Reddy KR. Rationale and design of the Hepatocellular carcinoma Early Detection Strategy study: A multi-center longitudinal initiative of the National Cancer Institute's Early Detection Research Network. Contemp Clin Trials. 2019 Jan;76:49-54.
- Rimola J, Davenport MS, Liu PS, Brown T, Marrero JA, McKenna BJ, Hussain HK. Diagnostic accuracy of MRI with extracellular vs. hepatobiliary contrast material for detection of residual hepatocellular carcinoma after locoregional treatment. Abdom Radiol (NY). 2019 Feb;44(2):549-558.
- Singal AG, Tiro JA, Murphy CC, Marrero JA, McCallister K, Fullington H, Mejias C, Waljee AK, Pechero Bishop W, Santini NO, Halm EA. Mailed Outreach Invitations Significantly Improve HCC Surveillance Rates in Patients With Cirrhosis: A Randomized Clinical Trial. Hepatology. 2019 Jan;69(1):121-130.
- Rich NE, Hester C, Odewole M, Murphy CC, Parikh ND, Marrero JA, Yopp AC, Singal AG. Racial and Ethnic Differences in Presentation and Outcomes of Hepatocellular Carcinoma. Clin Gastroenterol Hepatol. 2019 Feb;17(3):551-559.e1.
- Mack CL, Adams D, Assis DN, Kerkar N, Manns MP, Mayo MJ, Vierling JM, Alsawas M, Murad MH, Czaja AJ. Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the study of liver diseases. Hepatology. 2019 Dec 21.
- Harms MH, de Veer RC, Lammers WJ, Corpechot C, Thorburn D, Janssen HLA, Lindor KD, Trivedi PJ, Hirschfield GM, Pares A, Floreani A, Mayo MJ, Invernizzi P, Battezzati PM, Nevens F, Ponsioen CY, Mason AL, Kowdley KV, Hansen BE, Buuren HRV, van der Meer AJ. Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis. Gut. 2019 Dec 16. pii: gutjnl-2019-319057
- Murillo Perez CF, Hirschfield GM, Corpechot C, Floreani A, Mayo MJ, van der Meer A, Ponsioen CY, Lammers WJ, Parés A, Invernizzi P, Carbone M, Maria Battezzati P, Nevens F, Kowdley KV, Thorburn D, Mason AL, Trivedi PJ, Lindor KD, Bruns T, Dalekos GN, Gatselis NK, Verhelst X, Janssen HLA, Hansen BE, Gulamhusein A; GLOBAL PBC Study Group. Fibrosis stage is an independent predictor of outcome in primary biliary cholangitis despite biochemical treatment response. Aliment Pharmacol Ther. 2019 Nov;50(10):1127-1136.
- Gatselis NK, Goet JC, Zachou K, Lammers WJ, Janssen HLA, Hirschfield G, Corpechot C, Lindor KD, Invernizzi P, Mayo MJ, Battezzati PM, Floreani A, Pares A, Lygoura V, Nevens F, Mason AL, Kowdley KV, Ponsioen CY, Bruns T, Thorburn D, Verhelst X, Harms MH, van Buuren HR, Hansen BE, Dalekos GN; Global Primary Biliary Cholangitis Study Group. Factors Associated With Progression and Outcomes of Early Stage Primary Biliary Cholangitis. Clin Gastroenterol Hepatol. 2019 Aug 13. pii: S1542-3565(19)30888-2.
- Harms MH, van Buuren HR, Corpechot C, Thorburn D, Janssen HLA, Lindor KD, Hirschfield GM, Parés A, Floreani A, Mayo MJ, Invernizzi P, Battezzati PM, Nevens F, Ponsioen CY, Mason AL, Kowdley KV, Lammers WJ, Hansen BE, van der Meer AJ. Ursodeoxycholic acid therapy and liver transplant-free survival in patients with primary biliary cholangitis. J Hepatol. 2019 Aug;71(2):357-365.
- Mayo MJ, Pockros PJ, Jones D, Bowlus CL, Levy C, Patanwala I, Bacon B, Luketic V, Vuppalanchi R, Medendorp S, Dorenbaum A, Kennedy C, Novak P, Gu J, Apostol G, Hirschfield GM. A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. Hepatol Commun. 2019 Feb 1;3(3):365-381.
- Cheung AC, Lammers WJ, Murillo Perez CF, van Buuren HR, Gulamhusein A, Trivedi PJ, Lazaridis KN, Ponsioen CY, Floreani A, Hirschfield GM, Corpechot C, Mayo MJ, Invernizzi P, Battezzati PM, Parés A, Nevens F, Thorburn D, Mason AL, Carbone M, Kowdley KV, Bruns T, Dalekos GN, Gatselis NK, Verhelst X, Lindor KD, Lleo A, Poupon R, Janssen HLA, Hansen BE; Global PBC Study Group. Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis. Clin Gastroenterol Hepatol. 2019 Sep;17(10):2076-2084.e2.
- Hirschfield GM, Chazouillères O, Drenth JP, Thorburn D, Harrison SA, Landis CS, Mayo MJ, Muir AJ, Trotter JF, Leeming DJ, Karsdal MA, Jaros MJ, Ling L, Kim KH, Rossi SJ, Somaratne RM, DePaoli AM, Beuers U. Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial. J Hepatol. 2019 Mar;70(3):483-493.
- Lindor KD, Bowlus CL, Boyer J, Levy C, Mayo M. Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases. Hepatology. 2019 Jan;69(1):394-419.
- Mazhar K. The Future of Nonalcoholic Fatty Liver Disease Treatment. Med Clin North Am. 2019 Jan;103(1):57-69.
- Vatsalya V, Cave MC, Kong M, Gobejishvili L, Falkner KC, Craycroft J, Mitchell M, Szabo G, McCullough A, Dasarathy S, Radaeva S, Barton B, McClain CJ. Keratin 18 is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis. Clin Gastroenterol Hepatol. 2019 Dec 4. pii: S1542-3565(19)31390-4.
- Saha B, Tornai D, Kodys K, Adejumo A, Lowe P, McClain C, Mitchell M, McCullough A, Dasarathy S, Kroll-Desrosiers A, Barton B, Radaeva S, Szabo G. Biomarkers of Macrophage Activation and Immune Danger Signals Predict Clinical Outcomes in Alcoholic Hepatitis. Hepatology. 2019 Oct;70(4):1134-1149.
- Mitchell MC, Maddrey WC. Changing Times in Liver Transplantation for Alcohol-Associated Liver Disease. JAMA Intern Med. 2019 Mar 1;179(3):348-350.
- Pedersen MR, Tarlow BD, Mufti AR. CON: Patients With Decompensated Cirrhosis Listed for Liver Transplantation Should Be Treated Posttransplant. Clin Liver Dis (Hoboken). 2019 Aug 2;14(1):20-23.
2018 Publications
2018 Publications
- Deng Y, Wang ZV, Gordillo R, Zhu Y, Ali A, Zhang C, Wang X, Shao M, Zhang Z, Iyengar P, Gupta RK, Horton JD, Hill JA, Scherer PE. Adipocyte Xbp1s overexpression drives uridine production and reduces obesity. Mol Metab. May;11:1-17.
- Feagins LA, Weideman RA. GI Bleeding Risk of DOACs Versus Warfarin: Is Newer Better? Dig Dis Sci. Apr 18.
- Fedoseienko A, Wijers M, Wolters JC, Dekker D, Smit M, Huijkman N, Kloosterhuis N, Klug H, Schepers A, Willems van Dijk K, Levels JH, Billadeau DD, Hofker MH, van Deursen J, Westerterp M, Burstein E, Kuivenhoven JA, van de Sluis B. COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking. Circ Res. Mar 15.
- Gannavarapu BS, Lau SKM, Carter K, Cannon NA, Gao A, Ahn C, Meyer JJ, Sher DJ, Jatoi A, Infante R, Iyengar P. Prevalence and Survival Impact of Pretreatment Cancer-Associated Weight Loss: A Tool for Guiding Early Palliative Care. J Oncol Pract. Apr;14(4):e238-e250.
- Grant L, Tujios S, Singal AG. Outcomes of simultaneous liver-kidney transplantation: implications for patient selection. Curr Opin Organ Transplant. Apr;23(2):264-270.
- Gupta A, Mang N, Wei W, Ortwine J, Bhavan K, Johnson DH, Agrawal D. Supply Shortages: A Silver Lining. Am J Med. Jun;131(6):630-632.
- Gupta A, Alvarez KS, Agrawal D. Expanding the Scope of High-Value Practice Beyond Guideline-Based Care. JAMA Intern Med. Mar 1;178(3):429-430.
- Haque W, Minhajuddin A, Gupta A, Agrawal D. Conflicts of interest of editors of medical journals. PLoS One. May 18;13(5):e0197141.
- Harms MH, Lammers WJ, Thorburn D, Corpechot C, Invernizzi P, Janssen HLA, Battezzati PM, Nevens F, Lindor KD, Floreani A, Ponsioen CY, Mayo MJ, Dalekos GN, Bruns T, Parés A, Mason AL, Verhelst X, Kowdley KV, Goet JC, Hirschfield GM, Hansen BE, van Buuren HR. Major Hepatic Complications in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis: Risk Factors and Time Trends in Incidence and Outcome. Am J Gastroenterol. Feb;113(2):254-264.
- Heimbach JK, Kulik LM, Finn RS, Sirlin CB, Abecassis MM, Roberts LR, Zhu AX, Murad MH, Marrero JA. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology. Jan;67(1):358-380.
- Kelso M, Feagins LA. Can Smartphones Help Deliver Smarter Care for Patients With Inflammatory Bowel Disease? Inflamm Bowel Dis. Jun 4.
- Lau SKM, Gannavarapu BS, Carter K, Gao A, Ahn C, Meyer JJ, Sher DJ, Jatoi A, Infante R, Iyengar P. Impact of Socioeconomic Status on Pretreatment Weight Loss and Survival in Non-Small-Cell Lung Cancer. J Oncol Pract. 2018 Apr;14(4):e211-e220.
- Levy C, Bowlus CL, Carey E, Crawford JM, Deane K, Mayo MJ, Kim WR, Fried MW. A real-world observational cohort of patients with primary biliary cholangitis: TARGET-primary biliary cholangitis study design and rationale. Hepatol Commun. Mar 23;2(5):484-491.
- Linden AG, Li S, Choi HY, Fang F, Fukasawa M, Uyeda K, Hammer RE, Horton JD, Engelking LJ, Liang G. Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice. J Lipid Res. Mar;59(3):475-487.
- Marrero JA, Kulik LM, Sirlin C, Zhu AX, Finn RS, Abecassis MM, Roberts LR, Heimbach JK. Diagnosis, Staging and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. Apr 6.
- Murphy CC, Sigel BM, Yang E, Skinner CS, Halm EA, Gupta S, Sanders JM, McCallister K, Singal AG. Adherence to colorectal cancer screening measured as the proportion of time covered. Gastrointest Endosc. Feb 23.
- Meyer J, Singal AG. Stereotactic ablative radiotherapy for hepatocellular carcinoma: History, current status, and opportunities. Liver Transpl. Mar;24(3):420-427.
- Mokdad AA, Murphy CC, Pruitt SL, Mansour JC, Marrero JA, Singal AG, Yopp AC. Effect of hospital safety net designation on treatment use and survival in hepatocellular carcinoma. Cancer. Feb 15;124(4):743-751.
- Mosher CA, Brown GR, Weideman RA, Crook TW, Cipher DJ, Spechler SJ, Feagins LA. Incidence of Colorectal Cancer and Extracolonic Cancers in Veteran Patients With Inflammatory Bowel Disease. Inflamm Bowel Dis. Feb 15;24(3):617-623.
- Murillo Perez CF, Goet JC, Lammers WJ, Gulamhusein A, van Buuren HR, Ponsioen CY, Carbone M, Mason A, Corpechot C, Invernizzi P, Mayo MJ, Battezzati PM, Floreani A, Pares A, Nevens F, Kowdley KV, Bruns T, Dalekos GN, Thorburn D, Hirschfield G, LaRusso NF, Lindor KD, Zachou K, Poupon R, Trivedi PJ, Verhelst X, Janssen HLA, Hansen BE; GLOBAL PBC Study Group. Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history. Hepatology. May;67(5):1920-1930.
- Parikh ND, Scaglione S, Li Y, Powell C, Yerokun OA, Devlin P, Mumtaz S, Mittal S, Singal AG. A Comparison of Staging Systems for Hepatocellular Carcinoma in a Multicenter US Cohort. Clin Gastroenterol Hepatol. May;16(5):781-782.
- Parikh ND, Zhang P, Singal AG, Derstine BA, Krishnamurthy V, Barman P, Waljee AK, Su GL. Body Composition Predicts Survival in Patients with Hepatocellular Carcinoma Treated with Transarterial Chemoembolization. Cancer Res Treat. Apr;50(2):530-537.
- Potts A, Uchida A, Deja S, Berglund ED, Kucejova B, Duarte JAG, Fu X, Browning JD, Magnuson MA, Burgess SC. Cytosolic Phosphoenolpyruvate Carboxykinase as a Cataplerotic Pathway in the Small Intestine. Am J Physiol Gastrointest Liver Physiol. Apr 6.
- Rich NE, Hester C, Odewole M, Murphy CC, Parikh ND, Marrero JA, Yopp AC, Singal AG. Racial and Ethnic Differences in Presentation and Outcomes of Hepatocellular Carcinoma. Clin Gastroenterol Hepatol. May 31. pii: S1542-3565(18)30571-8.
- Rich NE, Oji S, Mufti AR, Browning JD, Parikh ND, Odewole M, Mayo H, Singal AG. Racial and Ethnic Disparities in Nonalcoholic Fatty Liver Disease Prevalence, Severity, and Outcomes in the United States: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. Feb;16(2):198-210. PMID: 28970148.
- Sanjeevaiah A, Kerr T, Beg MS. Approach and management of checkpoint inhibitor-related immune hepatitis. J Gastrointest Oncol. Feb;9(1):220-224.
- Singal AG, Corley DA, Kamineni A, Garcia M, Zheng Y, Doria-Rose PV, Quinn VP, Jensen CD, Chubak J, Tiro J, Doubeni CA, Ghai NR, Skinner CS, Wernli K, Halm EA. Patterns and predictors of repeat fecal immunochemical and occult blood test screening in four large health care systems in the United States. Am J Gastroenterol. May;113(5):746-754.
- Smith I, Schmidt R, Halm EA, Mansi IA. Do Statins Increase the Risk of Esophageal Conditions? Findings from Four Propensity Score-Matched Analyses. Clin Drug Investig. Feb;38(2):135-146.
- Sun X, Wang SC, Wei Y, Luo X, Jia Y, Li L, Gopal P, Zhu M, Nassour I, Chuang JC, Maples T, Celen C, Nguyen LH, Wu L, Fu S, Li W, Hui L, Tian F, Ji Y, Zhang S, Sorouri M, Hwang TH, Letzig L, James L, Wang Z, Yopp AC, Singal AG, Zhu H. Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer. Cancer Cell. Jan 8;33(1):151-152.
- Tzartzeva K, Obi J, Rich NE, Parikh ND, Marrero JA, Yopp A, Waljee AK, Singal AG. Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis. Gastroenterology. May;154(6):1706-1718.
- Waljee AK, Wiitala WL, Govani S, Stidham R, Saini S, Hou J, Feagins LA, Khan N, Good CB, Vijan S, Higgins PDR. Correction: Corticosteroid Use and Complications in a US Inflammatory Bowel Disease Cohort. PLoS One. May 9;13(5):e0197341.
- Wang J, Fedoseienko A, Chen B, Burstein E, Jia D, Billadeau DD. Endosomal receptor trafficking: Retromer and beyond. Traffic. 2018 Apr 18.
- Zhang S, Nguyen LH, Zhou K, Tu HC, Sehgal A, Nassour I, Li L, Gopal P, Goodman J, Singal AG, Yopp A, Zhang Y, Siegwart DJ, Zhu H. Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice Without Affecting Regeneration. Gastroenterology. Apr;154(5):1421-1434.
- Zhu W, Winter MG, Byndloss MX, Spiga L, Duerkop BA, Hughes ER, Büttner L, de Lima Romão E, Behrendt CL, Lopez CA, Sifuentes-Dominguez L, Huff-Hardy K, Wilson RP, Gillis CC, Tükel Ç, Koh AY, Burstein E, Hooper LV, Bäumler AJ, Winter SE. Precision editing of the gut microbiota ameliorates colitis. Nature. Jan 11;553(7687):208-211.
2017 Publications
2017 Publications
- Abraham BP, Ahmed T, Ali T. (2017) Inflammatory Bowel Disease: Pathophysiology and Current Therapeutic Approaches. Handb Exp Pharmacol. 239:115-146.
- Aday W, Mitchell MC, Casey LC. (2017) Alcoholic hepatitis: current trends in management. Curr Opin Gastroenterol. May;33(3):142-148.
- Agrawal D, Shoup V, Montgomery A, Wosik J, Rockey DC. (2017) Disposal of Endoscopic Accessories After Use: Do We Know and Do We Care? Gastroenterol Nurs. Jan/Feb;40(1):13-18.
- Agrawal D, Davis B, Quinn A, Thiele D. Should anti-LKM1 be routine for work-up of elevated liver enzymes? J Hepatol. Aug;67(2):417-418.
- Agrawal D, Sarode R. Complete Blood Count or Complete Blood Count with Differential: What's the Difference? Am J Med. Aug;130(8):915-916.
- Alekhina O, Burstein E, Billadeau DD. Cellular functions of WASP family proteins at a glance. J Cell Sci. Jul 15;130(14):2235-2241.
- Atiq O, Tiro J, Yopp AC, Muffler A, Marrero JA, Parikh ND, Murphy C, McCallister K, Singal AG. (2017) An assessment of benefits and harms of hepatocellular carcinoma surveillance in patients with cirrhosis. Hepatology. Apr;65(4):1196-1205.
- Atiq O, Tiro J, Yopp AC, Muffler A, Marrero JA, Parikh ND, Murphy C, McCallister K, Singal AG. (2017) HCC Surveillance: Striving for a Better Balance of Benefits and Harms. Hepatology. May 24.
- Berger JM, Loza Valdes A, Gromada J, Anderson N, Horton JD. Inhibition of PCSK9 does not improve lipopolysaccharide-induced mortality in mice. J Lipid Res. Aug;58(8):1661-1669.
- Bhatt DL, Grosser T, Dong JF, Logan D, Jeske W, Angiolillo DJ, Frelinger AL 3rd, Lei L, Liang J, Moore JE, Cryer B, Marathi U. Enteric Coating and Aspirin Nonresponsiveness in Patients With Type 2 Diabetes Mellitus. J Am Coll Cardiol. Feb 14;69(6):603-612.
- Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, Herrinton LJ, Klapproth JA, Quiros AJ, Seminerio J, Liu Z, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Dryden GW, Hanson JS, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kwon JH, Lazarev M, Li E, Mack D, Mannon P, Moulton DE, Newberry RD, Osuntokun BO, Patel AS, Saeed SA, Targan SR, Valentine JF, Wang MH, Zonca M, Rioux JD, Duerr RH, Silverberg MS, Cho JH, Hakonarson H, Zwick ME, McGovern DP, Kugathasan S. (2017) Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology. Jan;152(1):206-217.e2.
- Brennan GT, Melton SD, Spechler SJ, Feagins LA. (2017) Clinical Implications of Histologic Abnormalities in Ileocolonic Biopsies of Patients With Crohn's Disease in Remission. J Clin Gastroenterol. Jan;51(1):43-48.
- Brown TJ, Gentry C, Hammer ST, Hwang CS, Vusirikala M, Patel PA, Matevosyan K, Tujios SR, Mufti AR, Collins RH. Novel Application of Extracorporeal Photopheresis as Treatment of Graft-versus-Host Disease Following Liver Transplantation. ACG Case Rep J. Mar 29;4:e48.
- Cangemi DJ, Krill T, Weideman R, Cipher DJ, Spechler SJ, Feagins LA. A Comparison of the Rate of Gastrointestinal Bleeding in Patients Taking Non-Vitamin K Antagonist Oral Anticoagulants or Warfarin. Am J Gastroenterol. May;112(5):734-739.
- Cardoso FS, Gottfried M, Tujios S, Olson JC, Karvellas CJ; US Acute Liver Failure Study Group. Continuous renal replacement therapy is associated with reduced serum ammonia levels and mortality in acute liver failure. Hepatology. Aug 31 [Epub ahead of print]
- Chandrasekhara V, Khashab MA, Muthusamy VR, Acosta RD, Agrawal D, Bruining DH, Eloubeidi MA, Fanelli RD, Faulx AL, Gurudu SR, Kothari S, Lightdale JR, Qumseya BJ, Shaukat A, Wang A, Wani SB, Yang J, DeWitt JM. (2017) Adverse events associated with ERCP. Gastrointest Endosc. Jan;85(1):32-47.
- Chandrasekhara V, Koh J, Lattimer L, Dunbar KB, Ravich WJ, Clarke JO. (2017) Endoscopic balloon catheter dilatation via retrograde or static technique is safe and effective for cricopharyngeal dysfunction. World J Gastrointest Endosc. Apr 16;9(4):183-188.
- Cryer B, Barnett MA, Wagner J, Wilcox CM. Overuse and Misperceptions of Nonsteroidal Anti-inflammatory Drugs in the United States. Am J Med Sci. Nov;352(5):472-480.
- Cryer B, Drossman DA, Chey WD, Webster L, Habibi S, Wang M. Analysis of Nausea in Clinical Studies of Lubiprostone for the Treatment of Constipation Disorders. Dig Dis Sci. Dec;62(12):3568-3578.
- Deng Y, Wang ZV, Gordillo R, An Y, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE. An adipo-biliary-uridine axis that regulates energy homeostasis. Science. 2017 Mar 17;355(6330).
- Dunbar KB, Souza RF. Beyond Dysplasia Grade: The Role of Biomarkers in Stratifying Risk. Gastrointest Endosc Clin N Am. Jul;27(3):447-459.
- Duraiswamy S, Sheffield JS, Mcintire D, Leveno K, Mayo MJ. (2017) Updated Etiology and Significance of Elevated Bilirubin During Pregnancy: Changes Parallel Shift in Demographics and Vaccination Status. Dig Dis Sci. Feb;62(2):517-525.
- Engelking LJ, Cantoria MJ, Xu Y, Liang G. Developmental and extrahepatic physiological functions of SREBP pathway genes in mice. Semin Cell Dev Biol. Jul 20. pii: S1084-9521(17)30289-6.
- Farvardin S, Patel J, Khambaty M, Yerokun OA, Mok H, Tiro JA, Yopp AC, Parikh ND, Marrero JA, Singal AG. (2017) Patient-reported barriers are associated with lower hepatocellular carcinoma surveillance rates in patients with cirrhosis. Hepatology. Mar;65(3):875-884.
- Feagins LA, Waljee A, Hou JK, Gu P, Kanjo S, Rudrapatna V, Cipher DJ, Govani S, Gaidos J. Incidence of and Predictors for Early Discontinuation of Biological Therapies in Veteran Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. Aug;23(8):1434-1439.
- Feagins LA. Letter: the treatment of coronary artery disease in cirrhotics needs more thinking-author's reply. Aliment Pharmacol Ther. Sep;46(6):639.
- Feagins LA. Management of Anticoagulants and Antiplatelet Agents During Colonoscopy. Am J Med. Jul;130(7):786-795.
- Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert E, Hegele RA, Krauss RM, Raal FJ, Schunkert H, Watts GF, Borén J, Fazio S, Horton JD, Masana L, Nicholls SJ, Nordestgaard BG, van de Sluis B, Taskinen MR, Tokgözoglu L, Landmesser U, Laufs U, Wiklund O, Stock JK, Chapman MJ, Catapano AL. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. Aug 21;38(32):2459-2472.
- Ferris HA, Perry RJ, Moreira GV, Shulman GI, Horton JD, Kahn CR. Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism. Proc Natl Acad Sci U S A. Jan 31;114(5):1189-1194.
- Fitzgerald K, White S, Borodovsky A, Bettencourt BR, Strahs A, Clausen V, Wijngaard P, Horton JD, Taubel J, Brooks A, Fernando C, Kauffman RS, Kallend D, Vaishnaw A, Simon A. A Highly Durable RNAi Therapeutic Inhibitor of PCSK9. N Engl J Med. Jan 5;376(1):41-51.
- Gavini S, Borges LF, Finn RT, Lo WK, Goldberg HJ, Burakoff R, Feldman N, Chan WW. (2017) Lung disease severity in idiopathic pulmonary fibrosis is more strongly associated with impedance measures of bolus reflux than pH parameters of acid reflux alone. Neurogastroenterol Motil. May;29(5).
- Goossens N, Singal AG, King LY, Andersson KL, Fuchs BC, Besa C, Taouli B, Chung RT, Hoshida Y. Cost-Effectiveness of Risk Score-Stratified Hepatocellular Carcinoma Screening in Patients with Cirrhosis. Clin Transl Gastroenterol. Jun 22;8(6):e101.
- Gupta A, Arora N, Harris S, Naina HV. (2017) Dupuytren's contracture… or is it? Intern Emerg Med. Apr;12(3):409-410.
- Gupta A, Rahman A, Alvarez KS, Gard JW, Johnson DH, Agrawal D. Drug shortage leading to serendipitous adoption of high-value care practice. BMJ Qual Saf. Oct;26(10):852-854.
- Gupta A, Agrawal D, Croft C. The Harms of Empirical Bowel Regimens: A Teachable Moment. JAMA Intern Med. Oct 1;177(10):1518-1519.
- Hwang S, Nguyen AD, Jo Y, Engelking LJ, Brugarolas J, DeBose-Boyd RA. Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver. J Biol Chem. Jun 2;292(22):9382-9393.
- Huff-Hardy K, Bedair M, Vazquez R, Burstein E. Efficacy of Combination Vedolizumab and Ustekinumab for Refractory Crohn's Disease. Inflamm Bowel Dis. Oct;23(10):E49.
- Huo X, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Pham TH, Lynch JP, Wang DH, Bresalier RS, Spechler SJ, Souza SF. (2017) Aspirin prevents NF-κB activation and CDX2 expression stimulated by acid and bile salts in oesophageal squamous cells of patients with Barrett's oesophagus. Gut. Apr 25. pii: gutjnl-2016-313584.
- Infante RE, Radhakrishnan A. Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol. Elife. Apr 17;6.
- Kachhawa K, Kachhawa P, Varma M, Behera R, Agrawal D, Kumar S. (2017) Study of the Stability of Various Biochemical Analytes in Samples Stored at Different Predefined Storage Conditions at an Accredited Laboratory of India. J Lab Physicians. Jan-Mar;9(1):11-15.
- Karvellas CJ, Cardoso FS, Gottfried M, Reddy KR, Hanje AJ, Ganger D, Lee WM; US Acute Liver Failure Study Group. (2017) HBV-Associated Acute Liver Failure After Immunosuppression and Risk of Death. Clin Gastroenterol Hepatol. Jan;15(1):113-122.
- Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF; US Acute Liver Failure Study Group. (2017) Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure. Hepatology. Mar;65(3):938-949.
- Kelso M, Weideman RA, Cipher DJ, Feagins LA. Factors Associated With Length of Stay in Veterans With Inflammatory Bowel Disease Hospitalized for an Acute Flare. Inflamm Bowel Dis. Dec 19;24(1):5-11.
- Khan MA, Atiq O, Kubiliun N, Ali B, Kamal F, Nollan R, Ismail MK, Tombazzi C, Kahaleh M, Baron TH. Efficacy and safety of endoscopic gallbladder drainage in acute cholecystitis: Is it better than percutaneous gallbladder drainage? Gastrointest Endosc. Jan;85(1):76-87.
- Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD. (2017) Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. Cell Metab. Aug 1;26(2):394-406.
- Krill T, Brown G, Weideman RA, Cipher DJ, Spechler SJ, Brilakis E, Feagins LA. Patients with cirrhosis who have coronary artery disease treated with cardiac stents have high rates of gastrointestinal bleeding, but no increased mortality. Aliment Pharmacol Ther. Jul;46(2):183-192.
- Marrero JA, Singal AG. Direct-acting antivirals and recurrence of hepatocellular carcinoma. Liver Transpl. Sep;23(9):1099-1100.
- Martin J, Halm EA, Tiro JA, Merchant Z, Balasubramanian BA, McCallister K, Sanders JM, Ahn C, Bishop WP, Singal AG. (2017) Reasons for Lack of Diagnostic Colonoscopy After Positive Result on Fecal Immunochemical Test in a Safety-Net Health System. Am J Med. Jan;130(1):93.e1-93.e7.
- McNally KE, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, Langton P, Pearson N, Danson CM, Nägele H, Morris LL, Singla A, Overlee BL, Heesom KJ, Sessions R, Banks L, Collins BM, Berger I, Billadeau DD, Burstein E, Cullen PJ. Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling. Nat Cell Biol. 2017 Oct;19(10):1214-1225.
- Mitchell MC, Friedman LS, McClain CJ. (2017) Medical Management of Severe Alcoholic Hepatitis: Expert Review from the Clinical Practice Updates Committee of the AGA Institute. Clin Gastroenterol Hepatol. Jan;15(1):5-12.
- Mokdad AA, Hester CA, Singal AG, Yopp AC. (2017) Management of hepatocellular in the United States. Chin Clin Oncol. Apr;6(2):21.
- Mokdad AA, Singal AG, Marrero JA, Zhu H, Yopp AC. (2017) Vascular Invasion and Metastasis is Predictive of Outcome in Barcelona Clinic Liver Cancer Stage C Hepatocellular Carcinoma. J Natl Compr Canc Netw. Feb;15(2):197-204.
- Naveed M, Clary M, Ahn C, Kubiliun N, Agrawal D, Cryer B, Murphy C, Singal AG. Accuracy of Referring Provider and Endoscopist Impressions of Colonoscopy Indication. J Natl Compr Canc Netw. Jul;15(7):920-925.
- Nguyen AD, Dunbar KB. How to Approach Lymphocytic Esophagitis.. Curr Gastroenterol Rep. Jun;19(6):24.
- Nguyen AD, Spechler SJ, Shuler MN, Souza RF, Dunbar KB. Unique Clinical Features of Los Angeles Grade D Esophagitis Suggest That Factors Other Than Gastroesophageal Reflux Contribute to its Pathogenesis. J Clin Gastroenterol. Jun 21.
- Parekh J, Matei VM, Canas-Coto A, Friedman D, Lee WM; Acute Liver Failure Study Group. (2017) Budd-chiari syndrome causing acute liver failure: A multicenter case series. Liver Transpl. Feb;23(2):135-142.
- Parikh ND, Marshall VD, Singal AG, Nathan H, Lok AS, Balkrishnan R, Shahinian V. (2017) Survival and cost-effectiveness of sorafenib therapy in advanced hepatocellular carcinoma: An analysis of the SEER-Medicare database. Hepatology. Jan;65(1):122-133.
- Parikh ND, Singal AG, Lok AS, Balkrishnan R, Shahinian V, Marshall VD. (2017) Author Reply. Hepatology. May 3.
- Parikh ND, Marrero WJ, Wang J, Steuer J, Tapper EB, Konerman M, Singal AG, Hutton DW, Byon E, Lavieri MS. Projected increase in obesity and non-alcoholic-steatohepatitis-related liver transplantation waitlist additions in the United States. Hepatology. Aug 17.
- Parikh ND, Singal AG, Hutton DW. Cost effectiveness of regorafenib as second-line therapy for patients with advanced hepatocellular carcinoma. Cancer. Oct 1;123(19):3725-3731.
- Pearlman M, Covin Y, Schmidt R, Mortensen EM, Mansi IA. Statins and Lower Gastrointestinal Conditions: A Retrospective Cohort Study. J Clin Pharmacol. Aug;57(8):1053-1063.
- Pekow J, Meckel K, Dougherty U, Huang Y, Chen X, Almoghrabi A, Mustafi R, Ayaloglu-Butun F, Deng Z, Haider HI, Hart J, Rubin DT, Kwon JH, Bissonnette M. (2017) miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD. Clin Cancer Res. Sep 1;23(17):5281-5291.
- Reis SP, Sutphin PD, Singal AG, Grzybowski R, Fisher S, Ball C, Xi Y, Grewal S, Kalva SP. (2017) Tumor Enhancement and Heterogeneity Are Associated With Treatment Response to Drug-Eluting Bead Chemoembolization for Hepatocellular Carcinoma. J Comput Assist Tomogr. Mar/Apr;41(2):289-293.
- Rich NE, Tanriover B, Singal AG, Marrero JA. (2017) Outcomes of Simultaneous Liver Kidney Transplantation in Patients With Hepatocellular Carcinoma. Transplantation. Jan;101(1):e12-e19.
- Rich NE, Parikh ND, Singal AG. (2017) Hepatocellular Carcinoma and Liver Transplantation: Changing Patterns and Practices. Curr Treat Options Gastroenterol. Apr 19.
- Rich NE, Parikh ND, Singal AG. Overdiagnosis: An Understudied Issue in Hepatocellular Carcinoma Surveillance. Semin Liver Dis. Nov;37(4):296-304.
- Rich NE, Yopp AC, Singal AG. Medical Management of Hepatocellular Carcinoma. J Oncol Pract. Jun;13(6):356-364.
- Roberts DW, Lee WM, Hinson JA, Bai S, Swearingen CJ, Stravitz RT, Reuben A, Letzig L, Simpson PM, Rule J, Fontana RJ, Ganger D, Reddy KR, Liou I, Fix O, James LP. (2017) An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients With Acute Liver Injury or Failure. Clin Gastroenterol Hepatol. Apr;15(4):555-562.e3.
- Rong S, McDonald JG, Engelking LJ. Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine. J Lipid Res. Oct;58(10):1988-1998.
- Rong S, Cortés VA, Rashid S, Anderson NN, McDonald JG, Liang G, Moon YA, Hammer RE, Horton JD. Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice. Elife. Feb 28;6.
- Simmons O, Fetzer DT, Yokoo T, Marrero JA, Yopp A, Kono Y, Parikh ND, Browning T, Singal AG. (2017) Predictors of adequate ultrasound quality for hepatocellular carcinoma surveillance in patients with cirrhosis. Aliment Pharmacol Ther. Jan;45(1):169-177.
- Simmons O, Fetzer DT, Yokoo T, Marrero JA, Yopp A, Parikh N, Browning T, Singal AG. (2017) Editorial: ultrasound surveillance of hepatocellular carcinoma in the 21st century - authors' reply. Aliment Pharmacol Ther. Feb;45(4):562-563.
- Singal AG, Mittal S, Yerokun OA, Ahn C, Marrero JA, Yopp AC, Parikh ND, Scaglione SJ. (2017) Hepatocellular Carcinoma Screening Associated with Early Tumor Detection and Improved Survival Among Patients with Cirrhosis in the US. Am J Med. Feb 14. pii: S0002-9343(17)30128-6.
- Singal AG, Tiro JA, Marrero JA, McCallister K, Mejias C, Adamson B, Bishop WP, Santini NO, Halm EA. (2017) Mailed Outreach Program Increases Ultrasound Screening of Patients With Cirrhosis for Hepatocellular Carcinoma. Gastroenterology. Feb;152(3):608-615.e4.
- Singal AG, Tiro J, Li X, Adams-Huet B, Chubak J. Hepatocellular Carcinoma Surveillance Among Patients With Cirrhosis in a Population-based Integrated Health Care Delivery System. J Clin Gastroenterol. Aug;51(7):650-655.
- Singal AG. CON: Hepatocellular Carcinoma Surveillance: In Need of Higher-Quality Data. Am J Gastroenterol. Nov;112(11):1634-1635.
- Singal AG, Gupta S, Skinner CS, Ahn C, Santini NO, Agrawal D, Mayorga CA, Murphy C, Tiro JA, McCallister K, Sanders JM, Bishop WP, Loewen AC, Halm EA. Effect of Colonoscopy Outreach vs Fecal Immunochemical Test Outreach on Colorectal Cancer Screening Completion: A Randomized Clinical Trial. JAMA. Sep 5;318(9):806-815.
- Skinner CS, Ahn C, Halm EA, Bishop WP, McCallister K, Sanders JM, Farrell D, Santini N, Singal AG. Recommendation of colorectal cancer testing among primary care patients younger than 50 with elevated risk. Prev Med. Sep;102:20-23.
- Spierings ELH, Drossman DA, Cryer B, Mazen Jamal M, Losch-Beridon T, Mareya SM, Wang M. Efficacy and Safety of Lubiprostone in Patients with Opioid-Induced Constipation: Phase 3 Study Results and Pooled Analysis of the Effect of Concomitant Methadone Use on Clinical Outcomes. Pain Med. Jul 17.
- Starokadomskyy P, Sifuentes-Dominguez L, Gemelli T, Zinn AR, Dossi MT, Mellado C, Bertrand P, Borzutzky A, Burstein E. (2017) Evolution of the skin manifestations of X-linked Pigmentary Reticulate Disorder. Br J Dermatol. Apr 13.
- Tian C, Mayorga C, Agrawal D. Electronic Consultation Systems. Health Aff (Millwood). Jul 1;36(7):1348.
- Turer E, McAlpine W, Wang KW, Lu T, Li X, Tang M, Zhan X, Wang T, Zhan X, Bu CH, Murray AR, Beutler B. (2017) Creatine maintains intestinal homeostasis and protects against colitis. Proc Natl Acad Sci U S A. Feb 14;114(7):E1273-E1281.
- Turner BJ, Liang Y, Singal AG. (2017) FIB-4 and imaging for measuring fibrosis in hepatitis C virus. Eur J Gastroenterol Hepatol. Feb;29(2):192-198.
- Waljee AK, Rogers MA, Lin P, Singal AG, Stein JD, Marks RM, Ayanian JZ, Nallamothu BK. Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study. BMJ. Apr 12;357:j1415.
- Wang M, Sanda M, Comunale MA, Herrera H, Swindell C, Kono Y, Singal AG, Marrero J, Block T, Goldman R, Mehta A. (2017) Changes in the Glycosylation of Kininogen and the Development of a Kininogen-Based Algorithm for the Early Detection of HCC. Cancer Epidemiol Biomarkers Prev. May;26(5):795-803.
- Yadlapati R, Keswani RN, Dunbar KB, Gawron AJ, Gyawali CP, Kahrilas PJ, Katz PO, Katzka D, Spechler SJ, Tatum R, Pandolfino JE. (2017) Benchmarks for the interpretation of esophageal high-resolution manometry. Neurogastroenterol Motil. Apr;29(4).
- Yang JD, Dai J, Singal AG, Gopal P, Addissie B, Nguyen MH, Befeler AS, Reddy KR, Schwartz M, Harnois DM, Yamada H, Gores GJ, Feng Z, Marrero JA, Roberts LR. (2017) Improved Performance of Serum Alpha-Fetoprotein for Hepatocellular Carcinoma Diagnosis in HCV cirrhosis with Normal Alanine Transaminase. Cancer Epidemiol Biomarkers Prev. Mar 3. pii: cebp.0747.2016.
- Yek C, de la Flor C, Marshall J, Zoellner C, Thompson G, Quirk L, Mayorga C, Turner BJ, Singal AG, Jain MK. Effectiveness of direct-acting antiviral therapy for hepatitis C in difficult-to-treat patients in a safety-net health system: a retrospective cohort study. BMC Med. Nov 20;15(1):204.
- Yokoo T, Patel AD, Lev-Cohain N, Singal AG, Yopp AC, Pedrosa I. Extrahepatic metastasis risk of hepatocellular carcinoma based on α-fetoprotein and tumor staging parameters at cross-sectional imaging. Cancer Manag Res. Oct 16;9:503-511.
- Yopp AC, Parikh ND, Singal AG. (2017) Is the Hong Kong Liver Cancer Staging System Ready to Replace the Barcelona Clinic Liver Cancer System? Clin Gastroenterol Hepatol. May;15(5):756-758.
- Yopp AC, Marrero JA, Singal AG. (2017) Expansion of Criteria for Liver Transplantation in Hepatocellular Carcinoma: Better Patient Selection or a Slippery Slope? Ann Surg Oncol. Jul;24(7):1758-1760.
- Zimmer M, Bista P, Benson EL, Lee DY, Liu F, Picarella D, Vega RB, Vu CB, Yeager M, Ding M, Liang G, Horton JD, Kleemann R, Kooistra T, Morrison MC, Wielinga PY, Milne JC, Jirousek MR, Nichols AJ. CAT-2003: A novel sterol regulatory element-binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3-Leiden mice. Hepatol Commun. May 12;1(4):311-325.
2016 Publications
2016 Publications
- Aday W, Mayo MJ, Elliott A, Rockey DC. (2016) The Beneficial Effect of Beta-Blockers in Patients With Cirrhosis, Portal Hypertension and Ascites. Am J Med Sci. Feb;351(2):169-76.
- Agrawal D, Elsbernd B, Singal AG, Rockey D. (2016) Gastric residual volume after split-dose compared with evening-before polyethylene glycol bowel preparation. Gastrointest Endosc. Mar;83(3):574-80.
- Agrawal D. (2016) American Society of Anesthesiologist Classification-Higher Incentives for Higher Scores. JAMA Intern Med. Oct 1;176(10):1577-1578.
- Ali M, Yopp A, Gopal P, Beg MS, Zhu H, Lee W, Singal AG. (2016) A Variant in PNPLA3 Associated With Fibrosis Progression but not Hepatocellular Carcinoma in Patients With Hepatitis C Virus Infection. Clin Gastroenterol Hepatol. Feb;14(2):295-300.
- Apica BS, Seremba E, Rule J, Yuan HJ, Lee WM. (2016) High prevalence of occult hepatitis B infection in an African urban population. J Med Virol. Apr;88(4):674-80.
- Asanuma K, Huo X, Agoston A, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Pham TH, Wang DH, Iijima K, Shimosegawa T, Odze RD, Spechler SJ, Souza SF. (2016) In oesophageal squamous cells, nitric oxide causes S-nitrosylation of Akt and blocks SOX2 (sex determining region Y-box 2) expression. Gut. Sep;65(9):1416-26.
- Bangaru S, Thiele D, Sreenarasimhaiah J, Agrawal D. (2016) Severe Elevation of Liver Tests in Choledocholithiasis: An Uncommon Occurrence With Important Clinical Implications. J Clin Gastroenterol. Jul 25.
- Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A, Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B, Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH, van de Sluis B. (2016) CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun. Mar 11;7:10961.
- Bedimo R, Cutrell J, Zhang S, Drechsler H, Gao A, Brown G, Farukhi I, Castanon R, Tebas P, Maalouf NM. (2016) Mechanisms of bone disease in HIV and hepatitis C virus: impact of bone turnover, tenofovir exposure, sex steroids and severity of liver disease. AIDS. Feb 20;30(4):601-8.
- Chapman CG, Mariani CJ, Wu F, Meckel K, Butun F, Chuang A, Madzo J, Bissonnette MB, Kwon JH, Godley LA. (2016) Corrigendum: TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer. Sci Rep. Apr 28;6:24963.
- Chubak J, Garcia MP, Burnett-Hartman AN, Zheng Y, Corley DA, Halm EA, Singal AG, Klabunde CN, Doubeni CA, Kamineni A, Levin TR, Schottinger JE, Green BB, Quinn VP, Rutter CM; PROSPR consortium.. (2016) Time to Colonoscopy after Positive Fecal Blood Test in Four U.S. Health Care Systems. Cancer Epidemiol Biomarkers Prev. Feb;25(2):344-50.
- Crabb DW, Bataller R, Chalasani NP, Kamath PS, Lucey M, Mathurin P, McClain C, McCullough A, Mitchell MC, Morgan TR, Nagy L, Radaeva S, Sanyal A, Shah V, Szabo G; NIAAA Alcoholic Hepatitis Consortia. (2016) Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia. Gastroenterology. Apr;150(4):785-90.
- Dunbar KB, Agoston AT, Odze RD, Huo X, Pham TH, Cipher DJ, Castell DO, Genta RM, Souza SF, Spechler S. (2016) Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes. JAMA. May 17;315(19):2104-12.
- Feagins LA, Kane SV. (2016) Caring for Women with Inflammatory Bowel Disease. Gastroenterol Clin North Am. Jun;45(2):303-15.
- Feagins LA. (2016) An Apple a Day Keeps the Doctor Away, Provided You Eat the Apple. J Clin Gastroenterol. Feb;50(2):95-6.
- Fix OK, Liou I, Karvellas CJ, Ganger DR, Forde KA, Subramanian RM, Boylan A, Hanje J, Stravitz RT, Lee WM; Acute Liver Failure Study Group. (2016) Development and Pilot of a Checklist for Management of Acute Liver Failure in the Intensive Care Unit. PLoS One. May 13;11(5):e0155500.
- Geng Z, Agrawal D, Singal AG, Kircher S, Gupta S. (2016) Contained colonic perforation due to cecal retroflexion. World J Gastroenterol. Mar 21;22(11):3285-8.
- Geschwind JF, Kudo M, Marrero JA, Venook AP, Chen XP, Bronowicki JP, Dagher L, Furuse J, Ladrón de Guevara L, Papandreou C, Sanyal AJ, Takayama T, Ye SL, Yoon SK, Nakajima K, Lehr R, Heldner S, Lencioni R. (2016) TACE Treatment in Patients with Sorafenib-treated Unresectable Hepatocellular Carcinoma in Clinical Practice: Final Analysis of GIDEON. Radiology. May;279(2):630-40.
- Getachew Y, Cusimano FA, Gopal P, Reisman SA, Shay JW. (2016) The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury. Toxicol Sci. Jan;149(1):111-20.
- Govani SM, Wiitala WL, Stidham RW, Saini SD, Hou JK, Feagins LA, Sussman JB, Higgins PD, Waljee AK. (2016) Age Disparities in the Use of Steroid-sparing Therapy for Inflammatory Bowel Disease. Inflamm Bowel Dis. Aug;22(8):1923-8.
- Gu P, Theiss A, Han J, Feagins LA. (2016) Increased Cell Adhesion Molecules, PECAM-1, ICAM-3, or VCAM-1, Predict Increased Risk for Flare in Patients With Quiescent Inflammatory Bowel Disease. J Clin Gastroenterol. Aug 22.
- Gupta A, Ayyar B, Zia H, Chen W, Harris S, Naina HV. (2016) Hyaline-Vascular Type Castleman's Disease, Sarcoidosis, and Crohns Disease. Indian J Hematol Blood Transfus. Jun;32(Suppl 1):335-9.
- Gupta A, Gupta S, Harris S, Naina H. (2016) Hypothenar hammer syndrome. BMJ Case Rep. Jan 8;2016. pii: bcr2015213678.
- Gupta A, Harris S, Naina H. (2016) Femoral Pseudoaneurysm as a Complication of Infective Endocarditis. J Gen Intern Med. Apr;31(4):447-8.
- Hillman L, Gottfried M, Whitsett M, Rakela J, Schilsky M, Lee WM, Ganger D. (2016) Corrigendum: Clinical Features and Outcomes of Complementary and Alternative Medicine Induced Acute Liver Failure and Injury. Am J Gastroenterol. Oct;111(10):1504.
- Hirschfield GM, Gershwin ME, Strauss R, Mayo MJ, Levy C, Zou B, Johanns J, Nnane IP, Dasgupta B, Li K, Selmi C, Marschall HU, Jones D, Lindor K; PURIFI Study Group. (2016) Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid: A proof-of-concept study. Hepatology. Jul;64(1):189-99.
- Hou JK, Feagins LA, Waljee AK. (2016) Characteristics and Behavior of Elderly-onset Inflammatory Bowel Disease: A Multi-center US Study. Inflamm Bowel Dis. Sep;22(9):2200-5.
- Huo X, Agoston AT, Dunbar KB, Cipher DJ, Zhang X, Yu C, Cheng E, Zhang Q, Pham TH, Tambar UK, Bruick RK, Wang DH, Odze RD, Spechler SJ, Souza SF. (2016) Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD. Gut. Sep 30. pii: gutjnl-2016-312595.
- Hwang S, Hartman IZ, Calhoun LN, Garland K, Young GA, Mitsche MA, McDonald J, Xu F, Engelking L, DeBose-Boyd RA. (2016) Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver. J Biol Chem. Jun 24;291(26):13479-94.
- Jia D, Zhang JS, Li F, Wang J, Deng Z, White MA, Osborne DG, Phillips-Krawczak C, Gomez TS, Li H, Singla A, Burstein E, Billadeau DD, Rosen MK. (2016) Structural and mechanistic insights into regulation of the retromer coat by TBC1d5. Nat Commun. Nov 9;7:13305.
- ASGE Training Committee., Jorgensen J, Kubiliun N, Law JK, Al-Haddad MA, Bingener-Casey J, Christie JA, Davila RE, Kwon RS, Obstein KL, Qureshi WA, Sedlack RE, Wagh MS, Zanchetti D, Coyle WJ, Cohen J. (2016) Endoscopic retrograde cholangiopancreatography (ERCP): core curriculum. Gastrointest Endosc. Feb;83(2):279-89.
- Karvellas CJ, Tillman H, Leung AA, Lee WM, Schilsky ML, Hameed B, Stravitz RT, McGuire BM, Fix OK; United States Acute Liver Failure Study Group. (2016) Acute liver injury and acute liver failure from mushroom poisoning in North America. Liver Int. Jul;36(7):1043-50.
- Kingsley J, Karanth S, Revere FL, Agrawal D. (2016) Cost Effectiveness of Screening Colonoscopy Depends on Adequate Bowel Preparation Rates - A Modeling Study. PLoS One. Dec 9;11(12):e0167452.
- Koch DG, Tillman H, Durkalski V, Lee WM, Reuben A. (2016) Development of a Model to Predict Transplant-free Survival of Patients With Acute Liver Failure. Clin Gastroenterol Hepatol. Aug;14(8):1199-1206.e2.
- Kudo M, Lencioni R, Marrero JA, Venook AP, Bronowicki JP, Chen XP, Dagher L, Furuse J, Geschwind JF, Ladrón de Guevara L, Papandreou C, Sanyal AJ, Takayama T, Yoon SK, Nakajima K, Lehr R, Heldner S, Ye SL .(2016) Regional differences in sorafenib-treated patients with hepatocellular carcinoma: GIDEON observational study. Liver Int. Aug;36(8):1196-205.
- Marrero JA, Kudo M, Venook AP, Ye SL, Bronowicki JP, Chen XP, Dagher L, Furuse J, Geschwind JH, de Guevara LL, Papandreou C, Takayama T, Sanyal AJ, Yoon SK, Nakajima K, Lehr R, Heldner S, Lencioni R. (2016) Observational registry of sorafenib use in clinical practice across Child-Pugh subgroups: The GIDEON study. J Hepatol. Dec;65(6):1140-1147.
- Martin J, Kane SV, Feagins LA. (2016) Fertility and Contraception in Women With Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). Feb;12(2):101-9.
- Mokdad A, Browning T, Mansour JC, Zhu H, Singal AG, Yopp AC. (2016) Implementation of a Voice Messaging System is Associated With Improved Time-to-Treatment and Overall Survival in Patients With Hepatocellular Carcinoma. J Natl Compr Canc Netw. Jan;14(1):38-46.
- Mokdad AA, Singal AG, Yopp AC. (2016) Advances in Local and Systemic Therapies for Hepatocellular Cancer. Curr Oncol Rep. Feb;18(2):9.
- Mokdad AA, Zhu H, Marrero JA, Mansour JC, Singal AG, Yopp AC .(2016) Hospital Volume and Survival After Hepatocellular Carcinoma Diagnosis. Am J Gastroenterol. Jul;111(7):967-75.
- Mokdad AA, Singal AG, Yopp AC. (2016) JAMA PATIENT PAGE. Treatment of Liver Cancer. JAMA. Jan 5;315(1):100.
- Nadatani Y, Huo X, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Theiss A, Pham TH, Wang DH, Watanabe T, Fujiwara Y, Arakawa T, Spechler SJ, Souza SF. (2016) NOD-Like Receptor Protein 3 Inflammasome Priming and Activation in Barrett's Epithelial Cells. Cell Mol Gastroenterol Hepatol. Mar 19;2(4):439-453.
- Naveed M, Dunbar KB. (2016) Endoscopic imaging of Barrett's esophagus. World J Gastrointest Endosc. Mar 10;8(5):259-66.
- Nouveau S, Agrawal D, Kohli M, Bernerd F, Misra N, Nayak CS. (2016) Skin Hyperpigmentation in Indian Population: Insights and Best Practice. Indian J Dermatol. Sep-Oct;61(5):487-95.
- Okwara CJ, Petrasek J, Gibson M, Burstein E. (2016) Secondary Aortoesophageal Fistula Associated With Aneurysmal Graft Infection by Coxiella burnetii. ACG Case Rep J. Apr 15;3(3):169-71.
- Parikh ND, Yopp A, Singal AG. (2016) Controversies in criteria for liver transplantation in hepatocellular carcinoma. Curr Opin Gastroenterol. May;32(3):182-8.
- Parikh ND, Singal AG. (2016) The ITA.LI.CA Staging System: A Novel Staging System for Hepatocellular Carcinoma. PLoS Med. Apr 26;13(4):e1002005.
- Park JJ, Wong DK, Wahed AS, Lee WM, Feld JJ, Terrault N, Khalili M, Sterling RK, Kowdley KV, Bzowej N, Lau DT, Kim WR, Smith C, Carithers RL, Torrey KW, Keith JW, Levine DL, Traum D, Ho S, Valiga ME, Johnson GS, Doo E, Lok AS, Chang KM; Hepatitis B Research Network. (2016) Hepatitis B Virus--Specific and Global T-Cell Dysfunction in Chronic Hepatitis B. Gastroenterology. Mar;150(3):684-695.e5.
- Park JY, Dunbar KB, Mitui M, Arnold CA, Lam-Himlin DM, Valasek MA, Thung I, Okwara C, Coss E, Cryer B, Doern CD. (2016) Helicobacter pylori Clarithromycin Resistance and Treatment Failure Are Common in the USA. Dig Dis Sci. Aug;61(8):2373-80.
- Patel J, Yopp A, Waljee AK, Singal AG. (2016) Development and Internal Validation of a Model for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis. J Clin Gastroenterol. Feb;50(2):175-9.
- Reddy KR, Ellerbe C, Schilsky M, Stravitz RT, Fontana RJ, Durkalski V, Lee WM; Acute Liver Failure Study Group. (2016) Determinants of outcome among patients with acute liver failure listed for liver transplantation in the United States. Liver Transpl. Apr;22(4):505-15.
- Reuben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Smith A, Brown R, Crippin J, Harrison ME, Koch D, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hassanein T, Hanje AJ, Olson J, Subramanian R, Karvellas C, Hameed B, Sherker AH, Robuck P, Lee WM. ( 2016) Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Ann Intern Med. Jun 7;164(11):724-32.
- Rich N, Singal AG. (2016) Nonalcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma: A Potential New Challenge for Hepatocellular Carcinoma Surveillance. Gastroenterology. Dec;151(6):1246-1248.
- Rosen HR, Biggins SW, Niki T, Gralla J, Hillman H, Hirashima M, Schilsky M, Lee WM; Acute Liver Failure Study Group. (2016) Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure. Clin Gastroenterol Hepatol. Apr;14(4):606-612.e3.
- Satapati S, Kucejova B, Duarte JA, Fletcher JA, Reynolds L, Sunny NE, He T, Nair LA, Livingston KA, Fu X, Merritt ME, Sherry AD, Malloy CR, Shelton JM, Lambert J, Parks EJ, Corbin I, Magnuson MA, Browning JD, Burgess SC. (2016) Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. J Clin Invest. Apr 1;126(4):1605.
- Serper M, Wolf MS, Parikh NA, Tillman H, Lee WM, Ganger DR. (2016) Risk Factors, Clinical Presentation, and Outcomes in Overdose With Acetaminophen Alone or With Combination Products: Results From the Acute Liver Failure Study Group. J Clin Gastroenterol. Jan;50(1):85-91.
- Sims OT, Pollio DE, Hong BA, Jain MK, Brown GR, North CS. (2016) An assessment of concurrent drug and alcohol use among patients seeking treatment for hepatitis C. Ann Clin Psychiatry. Feb;28(1):31-6.
- Singal AG, Zhang P, Waljee AK, Ananthakrishnan L, Parikh ND, Sharma P, Barman P, Krishnamurthy V, Wang L, Wang SC, Su GL. (2016) Body Composition Features Predict Overall Survival in Patients With Hepatocellular Carcinoma. Clin Transl Gastroenterol. May 26;7:e172.
- Singal AG, Tiro J, Li X, Adams-Huet B, Chubak J. (2016) Hepatocellular Carcinoma Surveillance Among Patients With Cirrhosis in a Population-based Integrated Health Care Delivery System. J Clin Gastroenterol. Nov 18.
- Singal AG, Yopp AC. (2016) Hepatocellular carcinoma: How can we move from racial/ethnic disparities to a model of health equity? Cancer. Aug 15;122(16):2454-6.
- Singal AG, Gupta S, Tiro JA, Skinner CS, McCallister K, Sanders JM, Bishop WP, Agrawal D, Mayorga CA, Ahn C, Loewen AC, Santini NO, Halm EA. (2016) Outreach invitations for FIT and colonoscopy improve colorectal cancer screening rates: A randomized controlled trial in a safety-net health system. Cancer. Feb 1;122(3):456-63.
- Skinner CS, Gupta S, Halm EA, Wright S, McCallister K, Bishop W, Santini N, Mayorga C, Agrawal D, Moran B, Sanders JM, Singal AG. (2016) Development of the Parkland-UT Southwestern Colonoscopy Reporting System (CoRS) for evidence-based colon cancer surveillance recommendations. J Am Med Inform Assoc. Mar;23(2):402-6.
- Sreenarasimhaiah J. (2016) Endoscopic applications of cryospray ablation therapy-from Barrett's esophagus and beyond. World J Gastrointest Endosc. Aug 25;8(16):546-52.
- Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben-Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E. (2016) DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. May;17(5):495-504. doi: 10.1038/ni.3409.
- Stravitz RT, Ellerbe C, Durkalski V, Reuben A, Lisman T, Lee WM; Acute Liver Failure Study Group. (2016) Thrombocytopenia Is Associated With Multi-organ System Failure in Patients With Acute Liver Failure. Clin Gastroenterol Hepatol. Apr;14(4):613-620.e4. doi: 10.1016/j.cgh.2015.09.029.
- Tanriover B, MacConmara MP, Parekh J, Arce C, Zhang S, Gao A, Mufti A, Levea SL, Sandikci B, Ayvaci MU, Ariyamuthu VK, Hwang C, Mohan S, Mete M, Vazquez MA, Marrero JA. (2016) Simultaneous Liver Kidney Transplantation in Liver Transplant Candidates with Renal Dysfunction: Importance of Creatinine Level, Dialysis, and Organ Quality in Survival. Kidney Int Rep. Nov;1(4):221-229.
- Trivedi PJ, Lammers WJ, van Buuren HR, Parés A, Floreani A, Janssen HL, Invernizzi P, Battezzati PM, Ponsioen CY, Corpechot C, Poupon R, Mayo MJ, Burroughs AK, Nevens F, Mason AL, Kowdley KV, Lleo A, Caballeria L, Lindor KD, Hansen BE, Hirschfield GM; Global PBC Study Group. (2016) Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: a multicentre international study. Gut. Feb;65(2):321-9.
- Vance RB Jr, Kubiliun N, Dunbar KB. (2016) How Do We Manage Gastric Intestinal Metaplasia? A Survey of Clinical Practice Trends for Gastrointestinal Endoscopists in the United States. Dig Dis Sci. Jul;61(7):1870-8.
- Waljee AK, Wiitala WL, Govani S, Stidham R, Saini S, Hou J, Feagins LA, Khan N, Good CB, Vijan S, Higgins PD. (2016) Corticosteroid Use and Complications in a US Inflammatory Bowel Disease Cohort. PLoS One. Jun 23;11(6):e0158017.
- Wang M, Devarajan K, Singal AG, Marrero JA, Dai J, Feng Z, Rinaudo JA, Srivastava S, Evans A, Hann HW, Lai Y, Yang H, Block TM, Mehta A. (2016) The Doylestown Algorithm: A Test to Improve the Performance of AFP in the Detection of Hepatocellular Carcinoma. Cancer Prev Res (Phila). Feb;9(2):172-9.
- Wu F, Huang Y, Dong F, Kwon JH. (2016) Ulcerative Colitis-Associated Long Noncoding RNA, BC012900, Regulates Intestinal Epithelial Cell Apoptosis. Inflamm Bowel Dis. Apr;22(4):782-95.
- Yadlapati R, Keswani RN, Ciolino JD, Grande DP, Listernick ZI, Carlson DA, Castell DO, Dunbar KB, Gawron AJ, Gyawali CP, Katz PO, Katzka D, Lacy BE, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. (2016) A System to Assess the Competency for Interpretation of Esophageal Manometry Identifies Variation in Learning Curves. Clin Gastroenterol Hepatol. Jul 27. pii: S1542-3565(16)30445-1.
- Yadlapati R, Gawron AJ, Keswani RN, Bilimoria K, Castell DO, Dunbar KB, Gyawali CP, Jobe BA, Katz PO, Katzka DA, Lacy BE, Massey BT, Richter JE, Schnoll-Sussman F, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. (2016) Identification of Quality Measures for Performance of and Interpretation of Data From Esophageal Manometry. Clin Gastroenterol Hepatol. Apr;14(4):526-534.e1.
- Yeluru A, Cuthbert JA, Casey L, Mitchell MC. (2016) Alcoholic Hepatitis: Risk Factors, Pathogenesis, and Approach to Treatment. Alcohol Clin Exp Res. Feb;40(2):246-55.
- Zhang Z, Turer E, Li X, Zhan X, Choi M, Tang M, Press A, Smith SR, Divoux A, Moresco EM, Beutler B.( 2016) Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice. Proc Natl Acad Sci U S A. Oct 18;113(42):E6418-E6426.
2015 Publications
2015 Publications
- Adams MA, Hosmer AE, Wamsteker EJ, Anderson MA, Elta GH, Kubiliun NM, Kwon RS, Piraka CR, Scheiman JM, Waljee AK, Hussain HK, Elmunzer BJ. (2015) Predicting the likelihood of a persistent bile duct stone in patients with suspected choledocholithiasis: accuracy of existing guidelines and the impact of laboratory trends. Gastrointest Endosc. Jul;82(1):88-93.
- Agrawal D, Marull J, Tian C, Rockey DC. (2015) Contrasting Perspectives of Anesthesiologists and Gastroenterologists on the Optimal Time Interval between Bowel Preparation and Endoscopic Sedation. Gastroenterol Res Pract. 2015:497176.
- Ananthakrishnan AN, Kwon J, Raffals L, Sands B, Stenson WF, McGovern D, Kwon JH, Rheaume RL, Sandler RS. (2015) Variation in treatment of patients with inflammatory bowel diseases at major referral centers in the United States. Clin Gastroenterol Hepatol. Jun;13(6):1197-200.
- Atiq O, Patel N, Sreenarasimhaiah J, Agrawal D. (2015) Suture material in the common bile duct causing recurrent stones. Gastrointest Endosc. Sep;82(3):574-5.
- Augustyn A, Peng L, Singal AG, Yopp AC (2015). Surveillance for hepatocellular carcinoma secondary to cardiogenic cirrhosis in patients with congenital heart disease. Clin Res Cardiol. May;104(5):446-9.
- Basta G, Del Turco S, Navarra T, Lee WM; Acute Liver Failure Study Group. (2015) Circulating levels of soluble receptor for advanced glycation end products and ligands of the receptor for advanced glycation end products in patients with acute liver failure. Liver Transpl. Jun;21(6):847-54.
- Bernal W, Lee WM, Wendon J, Larsen FS, Williams R. (2015) Acute liver failure: A curable disease by 2024? J Hepatol. Apr;62(1 Suppl):S112-20.
- Burgess SC, Merritt ME, Jones JG, Browning JD, Sherry AD, Malloy CR. (2015) Limitations of detection of anaplerosis and pyruvate cycling from metabolism of [1-(13)C] acetate. Nat Med. Feb;21(2):108-9.
- Chapman CG, Mariani CJ, Wu F, Meckel K, Butun F, Chuang A, Madzo J, Bissonette MB, Kwon JH, Godley LA. (2015) TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer. Sci Rep. Dec 3;5:17568.
- Dalton-Fitzgerald E, Tiro J, Kandunoori P, Halm EA, Yopp A, Singal AG. (2015) Practice patterns and attitudes of primary care providers and barriers to surveillance of hepatocellular carcinoma in patients with cirrhosis. Clin Gastroenterol Hepatol. Apr;13(4):791-8.e1.
- Dubin PH, Sclair SN, Rico R, Boehme AK, Chen EY, Martin P, Lee WM.(2015) Low SVR rates in clinical practice for treating genotype 1 chronic hepatitis C with protease inhibitors boceprevir and telaprevir. Dig Dis Sci. Jan;60(1):272-4.
- Dunbar KB, Souza SF, Spechler SJ. (2015) The Effect of Proton Pump Inhibitors on Barrett's Esophagus. Gastroenterol Clin North Am. Jun;44(2):415-24.
- Elmunzer BJ, Singal AG, Sussman JB, Deshpande AR, Sussman DA, Conte ML, Dwamena BA, Rogers MA, Schoenfeld PS, Inadomi JM, Saini SD, Waljee AK. (2015) Comparing the effectiveness of competing tests for reducing colorectal cancer mortality: a network meta-analysis. Gastrointest Endosc. Mar;81(3):700-709.e3.
- Feagins LA, Flores A, Arriens C, Park C, Crook T, Reimold A, Brown G (2015). Nonalcoholic fatty liver disease: a potential consequence of tumor necrosis factor-inhibitor therapy. Eur J Gastroenterol Hepatol. Oct;27(10):1154-60.
- Flores A, Burstein E, Cipher DJ, Feagins LA. (2015) Obesity in Inflammatory Bowel Disease: A Marker of Less Severe Disease. Dig Dis Sci. Aug;60(8):2436-45.
- Fontana RJ, Hayashi PH, Barnhart H, Kleiner DE, Reddy KR, Chalasani N, Lee WM, Stolz A, Phillips T, Serrano J, Watkins PB; DILIN Investigators. (2015) Persistent liver biochemistry abnormalities are more common in older patients and those with cholestatic drug induced liver injury. Am J Gastroenterol. Oct;110(10):1450-9.
- Fontana RJ, Ellerbe C, Durkalski VE, Rangnekar A, Reddy RK, Stravitz T, McGuire B, Davern T, Reuben A, Liou I, Fix O, Ganger DR, Chung RT, Schilsky M, Han S, Hynan LS, Sanders C, Lee WM; US Acute Liver Failure Study Group. (2015) Two-year outcomes in initial survivors with acute liver failure: results from a prospective, multicentre study. Liver Int. Feb;35(2):370-80.
- Goebel M, Singal AG, Nodora J, Castañeda SF, Martinez E, Doubeni C, Laiyemo A, Gupta S.(2015) How can we boost colorectal and hepatocellular cancer screening among underserved populations? Curr Gastroenterol Rep. Jun;17(6):22.
- Goldstein JL, Cryer B. (2015) Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies. Drug Healthc Patient Saf. Jan 22;7:31-41.
- Goldstein JL, Cryer B. (2015) Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies. Drug Healthc Patient Saf. Jan 22;7:31-41.
- Gupta A, Harris S, Naina HV. (2015) Author Degrees in Medical Publishing: Choice or Convenience? South Med J. Nov;108(11):675.
- Gupta A, Harris S, Naina HV. (2015) The impact of physician posture during oncology patient encounters. J Cancer Educ. Jun;30(2):395-7.
- Gupta A, Harris S, Vernino S, Naina HV. (2015) Rituximab-based therapy and long-term control of autoimmune autonomic ganglionopathy. Clin Auton Res. Aug;25(4):255-8.
- Hayashi PH, Fontana RJ, Chalasani NP, Stolz AA, Talwalkar JA, Navarro VJ, Lee WM, Davern TJ, Kleiner DE, Gu J, Hoofnagle JH; US Drug-Induced Liver Injury Network Investigators. (2015) Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity. Clin Gastroenterol Hepatol. Sep;13(9):1676-82.e1.
- Hirschfield GM, Mason A, Luketic V, Lindor K, Gordon SC, Mayo M, Kowdley KV, Vincent C, Bodhenheimer HC Jr, Parés A, Trauner M, Marschall HU, Adorini L, Sciacca C, Beecher-Jones T, Castelloe E, Böhm O, Shapiro D. (2015) Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid. Gastroenterology. Apr;148(4):751-61.e8.
- Jodorkovsky D, Macura KJ, Gearhart SL, Dunbar KB, Stein EM, Clarke JO. (2015) High-resolution anorectal manometry and dynamic pelvic magnetic resonance imaging are complementary technologies. J Gastroenterol Hepatol. Jan;30(1):71-4.
- Jones RD, Lopez AM, Tong EY, Posey KS, Chuang JC, Repa JJ, Turley SD. (2015) Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice. Steroids. Jan;93:87-95.
- Kahn B, Freeland Z, Gopal P, Agrawal D, Mayorga CA, MIthani R, Skinner CS, Halm EA, Singal AG. (2015) Predictors of guideline concordance for surveillance colonoscopy recommendations in patients at a safety-net health system. Cancer Causes Control. Nov;26(11):1653-60.
- Karvellas CJ, Todd Stravitz R, Battenhouse H, Lee WM, Schilsky ML; US Acute Liver Failure Study Group. (2015) Therapeutic hypothermia in acute liver failure: a multicenter retrospective cohort analysis. Liver Transpl. Jan;21(1):4-12.
- Karvellas CJ, Stravitz RT, Battenhouse H, Lee WM, Schilsky ML. (2015) Reply: To PMID 25308108. Liver Transpl. Jul;21(7):1009-10.
- Kaur G, Leslie EM, Tillman H, Lee WM, Swanlund DP, Karvellas CJ; US Acute Liver Failure Study Group. (2015) Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors. PLoS One. Sep 25;10(9):e0139299.
- Khambaty M, Singal AG, Gopal P. (2015 ) Spirochetes as an almost forgotten cause of hepatitis. Clin Gastroenterol Hepatol. Feb;13(2):A21-2.
- Kubiliun NM, Adams MA, Akshintala VS, Conte ML, Cote GA, Cotton PB, Dumonceau JM, Elta GH, Fogel EL, Freeman ML, Lehman GA, Naveed M, Romagnuolo J, Scheiman JM, Sherman S, Singh VK, Elmunzer BJ; United States Cooperative for Outcomes Research in Endoscopy (USCORE). (2015) Evaluation of Pharmacologic Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Systematic Review. Clin Gastroenterol Hepatol. Jul;13(7):1231-9; quiz e70-1.
- Lammers WJ, Hirschfield GM, Corpechot C, Nevens F, Lindor KD, Janssen HL, Floreani A, Ponsioen CY, Mayo MJ, Invernizzi P, Battezzati PM, Parés A, Burroughs AK, Mason AL, Kowdley KV, Kumagi T, Harms MH, Trivedi PJ, Poupon R, Cheung A, Lleo A, Caballeria L, Hansen BE, van Buuren HR; Global PBC Study Group. (2015) Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy. Gastroenterology. Dec;149(7):1804-1812.e4.
- Li H, Starokadomskyy P, Burstein E. (2015) Methodology to study NF-κB/RelA ubiquitination in vivo. Methods Mol Biol. 1280:371-81.
- Lopez AM, Chuang JC, Posey KS, Ohshiro T, Tomoda H, Rudel LL, Turley SD. (2015) PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice. J Pharmacol Exp Ther. Nov;355(2):159-67.
- Martin J, Khatri G, Gopal P, Singal AG. (2015) Accuracy of ultrasound and noninvasive markers of fibrosis to identify patients with cirrhosis. Dig Dis Sci. Jun;60(6):1841-7.
- Mayo MJ. (2015 ) Predicting Outcomes of Primary Biliary Cholangitis Using the GLOBE Score. Gastroenterol Hepatol (N Y). Dec;11(12):842-4.
- McCarthy ST, Tujios S, Fontana RJ, Rahnama-Moghadam S, Elmunzer BJ, Kwon RS, Wamsteker EJ, Anderson MA, Scheiman JM, Elta GH, Piraka CR. (2015) Endoscopic Transpapillary Gallbladder Stent Placement Is Safe and Effective in High-Risk Patients Without Cirrhosis. Dig Dis Sci. Aug;60(8):2516-22.
- McFarlane MR, Cantoria MJ, Linden AG, January BA, Liang G, Engelking LJ. (2015) Scap is required for sterol synthesis and crypt growth in intestinal mucosa. J Lipid Res. Aug;56(8):1560-71.
- Mehta A, Singal AG. ( 2015) Hepatocellular Carcinoma Surveillance: Does Alpha-Fetoprotein Have a Role? Gastroenterology. Sep;149(3):816-7.
- Meier A, Yopp A, Mok H, Kandunoori P, Tiro J, Singal AG. (2015) Role functioning is associated with survival in patients with hepatocellular carcinoma. Qual Life Res. Jul;24(7):1669-75.
- Mokdad AA, Singal AG, Yopp AC. (2015) JAMA PATIENT PAGE. Liver Cancer. JAMA. Dec 22-29;314(24):2701.
- Naveed M, Rossen JL, Dunbar K, Ramzan Z, Kukreja S. (2015) Diagnosis and Management of an Esophagogastric Fistula as a Rare Complication of Nissen Fundoplication. ACG Case Rep J. Jan 16;2(2):68-9.
- Parikh ND, Waljee AK, Singal AG. (2015) Downstaging hepatocellular carcinoma: A systematic review and pooled analysis. Liver Transpl. Sep;21(9):1142-52.
- Park JY, Dunbar KB, Vermulapalli R, Wang DH, Zhang PJ .(2015) Human epidermal growth factor receptor 2 testing in gastric and gastroesophageal junction adenocarcinomas: role of the gastroenterologist. Gastrointest Endosc. Apr;81(4):977-82.
- Patel N, Yopp AC, Singal AG. (2015) Diagnostic delays are common among patients with hepatocellular carcinoma. J Natl Compr Canc Netw. May;13(5):543-9.
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