Computational and Systems Biology Faculty


Gaudenz Danuser, Ph.D.

Gaudenz Danuser, Ph.D., Co-Chair
Danuser Lab
Research Interests: Regulation of cell morphogenesis during metastasis; roles of mechanics in cell survival and drug resistance

Nick Grishin, Ph.D.

Nick Grishin, Ph.D., Co-Chair
Grishin Lab 
Research Interests: Computational biology; analysis of protein sequences and structures

Maria Chahrour, Ph.D.

Maria Chahrour, Ph.D.
Assistant Professor
Research Interests: Genomic, genetic, and molecular approaches to autism spectrum disorders

Lindsay Cowell, Ph.D.

Lindsay Cowell, Ph.D., Associate Professor
Research Interests: Somatic diversification of antigen receptor genes; repertoire characteristics as biomarkers of immune status and disease; host-pathogen interactions

Dustin Hancks, Ph.D.

Dustin Hancks, Ph.D., Assistant Professor
Hancks Lab
Research Interests: Host-pathogen interactions, genetic conflicts, positive selection​, genome evolution, innate immunity, evolutionary immunology, horizontal gene transfer, poxviruses, mutation, genetic disease, genomics ​

Gary Hon, Ph.D.

Gary Hon, Ph.D.
Assistant Professor
Hon Lab
Research Interests: Developing (epi)genomic/bioinformatic tools to assess and predict the functions of regulatory elements, epigenetic biomarkers of disease state, epigenetics in development and disease, global regulation of mammalian gene expression, non-coding genome function

Khuloud Jaqaman, Ph.D.

Khuloud Jaqaman, Ph.D., Assistant Professor
Jaqaman Lab
Research Interests: Quantitative spatiotemporal structure-function relationships of multi-molecular assemblies; linking molecular and cellular behavior across multiple scales; computational image analysis and mathematical modeling

Steve Jiang, Ph.D.

Steve Jiang, Ph.D., Professor
Jiang Lab 
Research Interests: Personal high performance computing device to improve the efficiency and more importantly, to change the way we diagnose and treat patients in cancer radiotherapy

Lukasz Joachimiak, Ph.D.

Lukasz Joachimiak, Ph.D., Assistant Professor
Joachimiak Lab
Research Interests: Molecular recognition in protein folding, chaperone structural biology, and neurodegeneration

Daehwan Kim, Ph.D.

Daehwan Kim, Ph.D., Chair
Associate Professor
Kim Lab
Research Interests: DNA and RNA Sequence Alignment, Graph Alignment to Population of Genomes, Genotyping, Personalized Medicine

Lee Kraus, Ph.D.

W. Lee Kraus, Ph.D., Professor
Kraus Lab 
Research Interests: Computational genomics. Using molecular, genetic, genomic, and computational approaches to understanding signal-regulated gene expression. Integrating data from different genomic platforms using computational approaches.

Bo Li, Ph.D.

Bo Li, Ph.D., Chair
Associate Professor
Li Lab
Research Interests: Cancer immunology; Statistical modeling for cancer genomics data; Data mining; Tumor-infiltrating immune repertoire profiling

Milo Lin, Ph.D.

Milo Lin, Ph.D., Assistant Professor
Lin Lab
Research Interests: Optimization in conformational and network space.

Zbyszek Otwinowski, Ph.D.

Zbyszek Otwinowski, Ph.D., Professor
Otwinowski Lab
Research Interests: Development of methods to study next generation sequencing and X-ray crystallographic data

Satwik Rajaram, Ph.D.

Satwik Rajaram, Ph.D., Chair
Associate Professor
Rajaram Lab
Research Interests: Understanding tissue organization via machine learning; Intra-tumor heterogeneity; Computational image analysis and spatial statistics

Kimberly Reynolds, Ph.D.

Kimberly Reynolds, Ph.D., Assistant Professor
Reynolds Lab
Research Interests: Statistical analysis and rational design of cellular systems

Luke Rice, Ph.D.

Luke Rice, Ph.D., Associate Professor
Rice Lab
Research Interests: Integrating structure, kinetics, and computation to understand the molecular determinants and regulatory mechanisms of microtubule dynamics

Elliott Ross, Ph.D.

Elliott Ross, Ph.D., Professor
Ross Lab
Research Interests: Cellular information processing; molecular mechanisms of G protein-mediated signaling: amplification, selectivity, response kinetics and signal integration

Guanghua Xiao, Ph.D.

Guanghua Xiao, Ph.D., Associate Professor
Xiao Lab
Research Interests: Improving treatments for cancer by applying computer science and statistical methodologies to analyzing high-throughput biological data. New models and tools are currently in development to assist the investigation of disease mechanisms and their related diagnostic innovations.

Yang Xie, Ph.D.

Yang Xie, Ph.D., Associate Professor
Xie Lab
Research Interests: Biostatistics, bioinformatics, statistical genomics, clinical trial design, and biomarker studies.

Chao Xing, Ph.D.

Chao Xing, Ph.D., Associate Professor
Xing Lab
Research Interests:  Statistical genetics, genetic epidemiology, bioinformatics, gene mapping for complex traits.

Xiaowei Zhan, Ph.D.

Xiaowei Zhan, Ph.D., Assistant Professor
Research Interests: Statistical genetics, forward genetics screening, statistical computation, next-generation sequencing, genetic association studies

Associate Members

These faculty members do not accept graduate students. They participate in teaching, co-mentoring, exam and dissertation committees, and all other program responsibilities.

Dominika Borek, Ph.D.

Dominika Borek, Ph.D., Assistant Professor
Research Interests:  Development of methods to study heteroplasmy and the somatic evolution of cancers.

Murat Cobanoglu, Ph.D.

Murat Cobanoglu, Ph.D., Assistant Professor
Research Interests: Active machine learning driven cancer drug discovery

Dan Heitjan, Ph.D.

Dan Heitjan, Ph.D., Professor
Research Interests: Clinical trial design and analysis; health economics; incomplete data; statistical modeling

Julia Kozlitina, Ph.D.

Julia Kozlitina, Ph.D., Assistant Professor
Research Interests: Statistics, statistical genetics, genetic epidemiology, genome-wide association studies

Tao Wang, Ph.D.

Tao Wang, Ph.D., Assistant Professor
Research Interests: Mouse genetics, immunology, cancer genomics, imaging analysis