Recent Dissertation Titles

Listed below are the dissertation thesis titles authored by doctoral degree conferees in the past two academic years. Titles are listed with student’s name and mentor.

"Role of IL-17A and Acaid in the Maintenance of Corneal Immune Privilege"
Khrishen Cunnusamy
Mentor: Jerry Y. Niederkorn, Ph.D.
"Transcriptional Regulation of Adult Neurogenesis by NRSF/REST and NeuroD1"
Kerstin Maria Ure
Mentor: Jenny Hsieh, Ph.D.
"Structural and Functional Studies of Munc18 and SNARE Proteins"
Yi Xu
Mentor: Jose Rizo-Rey, Ph.D.
"Small Molecule Regulators of ENTPD5, an ER Enzyme in the PTEN/AKT Pathway"
Song Huang
Mentor: Xiaodong Wang, Ph.D.
"The Endoplasmic Reticulum UDPase ENTPD5 Promotes Cancer Cell Growth and Survival in the P13K/PTEN Pathway"
Zhirong Shen
Mentor: Xiaodong Wang, Ph.D.
"Design and Development of Artificial Zinc Finger Transcription Factors and Zinc Finger Nucleases to the hTERT Locus"
Kimberly Anne Wilson
Mentor: Matthew H. Porteus, M.D., Ph.D.
"Ca2 Signaling in the Near Plasma Membrane Microdomain of Non-Excitable Cells"
Jian Yao
Mentor: Shmuel Muallem, Ph.D.
"Regulation of Metabolism by Fibroblast Growth Factor 21"
Paul Anthony Dutchak
Mentors: Steven Kliewer, Ph.D./David Mangelsdorf, Ph.D.
"Novel Insights into the Regulation of Autophagy in Saccharomyces Cerevisiae"
Xi Wu
Mentor: Benjamin P. Tu, Ph.D.
"Dynamic Changes in Collagen Organization Modulate Cervical Remodeling during Pregnancy and Parturition: New Insights and the Potential for Improved Clinical Tools to Combat Preterm Birth"
Meredith Lynne Akins
Mentor: Mala Mahendroo, Ph.D.
"How to MEND a Broken Heart: Massive ENDocytosis and the Role of Lipidic Forces in Membrane Trafficking"
Jon Michael Fine
Mentor: Donald Hilgemann, Ph.D.
"Role of Vitamin D Receptor in Insulin Secretion and Beta Cell Function
Lilja Kjalarsdottir
Mentor: Joyce Repa, Ph.D.
"Orexin Signaling and the Prevention of Diet-Induced Obesity:
Allen L. Tsai
Mentor: Masashi Yanagisawa, Ph.D.
"Discovery and Development of Predictive Biomarkers for the Personalization of Pemetrexed Therapy in Non-Small Cell Lung Cancer"
Misty D. Watson (Shields)
Mentor: John D. Minna, M.D.
"Understanding the Molecular Basis for FGF15/19 and FGF21 Actions on Energy Homeostasis"
Jamie Boney-Montoya
Mentors: Steven Kliewer, Ph.D./David Mangelsdorf, Ph.D.
"The Liver-Derived Endocrine Hormone FGF21 Alters Metabolism and Diurnal Behavior via the Nervous System"
Angie Lynn Bookout
Mentors: Steven Kliewer, Ph.D./David Mangelsdorf, Ph.D./Joel K. Elmquist, Ph.D.
"Phosphate Overload Inhibits Female Fertility in Mice"
Addie Smith Dickson
Mentor: Makoto Kuro-o, M.D., Ph.D.
"Role of Insig-Mediated Cholesterol Homeostasis in the Development of the Palate and Hair Follicles in Mice"
Bret Evers
Mentors: Michael Brown, M.D./Joseph Goldstein, M.D.