Student Profile in Microtubule Polymerization Dynamics
Tasia Bos
Molecular Biophysics Graduate Program
Mentors: Luke Rice, Ph.D.
Undergraduate Degree: Biochemistry and Biology
Undergraduate Institution: West Texas A&M University
Hometown: Borger, TX
Awards/Fellowships: Graduate: Molecular Biophysics T32 Training Grant Post-baccalaureate: VCU Postbaccalaureate Research Education Program (PREP) Affiliate, 2020 ABRCMS Best Poster in Cancer Biology Award Undergraduate: WTAMU Ronald E. McNair Postbaccalaureate Achievement Program Scholar
How did you become interested in science and/or research?
Science was always my favorite subject as a kid, and I knew that I wanted a career in STEM. I changed my career path several times as an undergraduate student. I switched from engineering, to pre-med, and finally to biochemistry. Once I had my first research experience, I knew that being a research scientist was my place in STEM.
Please describe your research.
Microtubules are dynamic polymers of αβ-tubulin subunits that are required for cell division, are essential for organizing the interior of eukaryotic cells, and are direct targets of anti-cancer drugs. I am interested in discovering how the biochemical and structural properties of αβ-tubulin and their interactions with the microtubule lattice influence how microtubules grow and shrink. I use in vitro reconstitution and imaging to measure microtubule growing and shrinking, and my work will combine quantitative biochemistry and cryo-EM to uncover the underlying mechanisms of microtubule dynamics.
Why did you choose UTSW for graduate school?
I had a great experience during the recruiting session at ABRCMS. I learned about the various student organizations, the support graduate students receive, and the plethora of core facilities and diverse research interests at UTSW. After my interviews, I was drawn to the collaborative environment and state of the art instruments. There were many research interests and labs to choose from, so I knew that I would have no trouble finding my place at UTSW.
What do you think makes the Molecular Biophysics Graduate Program is one of the best?
The course work provides a solid foundation for students new to the field and lets experienced students build upon their existing knowledge. The program fosters a collaborative and interdisciplinary environment, so students are not limited. The staff and faculty are highly knowledgeable and eager to help students become better scientists.
What do you love about the Molecular Biophysics Graduate Program?
The staff and faculty are very helpful. Because the program is collaborative and interdisciplinary, the program produces well-rounded scientists.
– Tasia Bos
