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Computational and Systems Biology Faculty

Program Co-Chairs

Gaudenz Danuser, Ph.D.
Gaudenz Danuser, Ph.D.

Professor

Research Interests: Computer vision; computational cell biology; regulation of cell morphogenesis; roles of cell morphogenesis in cancer

Nick Grishin, Ph.D.
Nick Grishin, Ph.D.

Professor

Research Interests: Computational biology; analysis of protein sequences and structures

Faculty

Maria Chahrour, Ph.D.

Assistant Professor

Research Interests: Genomic, genetic, and molecular approaches to autism spectrum disorders

Maria Chahrour, Ph.D.
Lindsay Cowell, Ph.D.

Associate Professor

Research Interests: Somatic diversification of antigen receptor genes; repertoire characteristics as biomarkers of immune status and disease; host-pathogen interactions

Lindsay Cowell, Ph.D.
Dustin Hancks, Ph.D.

Assistant Professor

Research Interests: Host-pathogen interactions, genetic conflicts, positive selection​, genome evolution, innate immunity, evolutionary immunology, horizontal gene transfer, poxviruses, mutation, genetic disease, genomics

Dustin Hancks, Ph.D.
Gary Hon, Ph.D.

Assistant Professor

Research Interests: Developing (epi)genomic/bioinformatic tools to assess and predict the functions of regulatory elements, epigenetic biomarkers of disease state, epigenetics in development and disease, global regulation of mammalian gene expression, non-coding genome function

Gary Hon, Ph.D.
Khuloud Jaqaman, Ph.D.

Assistant Professor

Research Interests: Quantitative spatiotemporal structure-function relationships of multi-molecular assemblies; linking molecular and cellular behavior across multiple scales; computational image analysis and mathematical modeling

Khuloud Jaqaman, Ph.D.
Steve Jiang, Ph.D.

Professor

Research Interests: Personal high performance computing device to improve the efficiency and more importantly, to change the way we diagnose and treat patients in cancer radiotherapy

Steve Jiang, Ph.D.
Lukasz Joachimiak, Ph.D.

Assistant Professor

Research Interests: Molecular recognition in protein folding, chaperone structural biology, and neurodegeneration

Lukasz Joachimiak, Ph.D.
Daehwan Kim, Ph.D.

Assistant Professor

Research Interests: DNA and RNA sequence alignment, graph alignment to population of genomes, genotyping, personalized medicine

Daehwan Kim, Ph.D.
Genevieve Konopka, Ph.D.

Associate Professor

Research Interests: Comparative genomics, epigenetics, and alternative splicing analyses relevant to brain evolution and cognitive disorders

Genevieve Konopka, Ph.D.
W. Lee Kraus, Ph.D.

Professor

Research Interests: Computational genomics. Using molecular, genetic, genomic, and computational approaches to understanding signal-regulated gene expression. Integrating data from different genomic platforms using computational approaches

W. Lee Kraus, Ph.D.
Bo Li, Ph.D.

Assistant Professor

Research Interests: Cancer immunology; statistical modeling for cancer genomics data; data mining; tumor-infiltrating immune repertoire profiling

Bo Li, Ph.D.
Milo Lin, Ph.D.

Assistant Professor

Research Interests: Optimization in conformational and network space.

Milo Lin, Ph.D.
Albert Montillo, Ph.D.

Assistant Professor

Research Interests: Developing state-of-the-art machine learning approaches to extract radiological imaging and imaging-genomic biomarkers and to engender personalized prognostics in neuroscience and oncological applications

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Zbyszek Otwinowski, Ph.D.

Professor

Research Interests: Development of methods to study next generation sequencing and X-ray crystallographic data

Zbyszek Otwinowski, Ph.D.
Satwik Rajaram, Ph.D.

Assistant Professor

Research Interests: Understanding tissue organization via machine learning; intra-tumor heterogeneity; computational image analysis and spatial statistics

Satwik Rajaram, Ph.D.
Kimberly Reynolds, Ph.D.

Assistant Professor

Research Interests: Statistical analysis and rational design of cellular systems

Kimberly Reynolds, Ph.D.
Luke Rice, Ph.D.

Associate Professor

Research Interests: Integrating structure, kinetics, and computation to understand the molecular determinants and regulatory mechanisms of microtubule dynamics

Luke Rice, Ph.D.
Elliott Ross, Ph.D.

Professor

Research Interests: Cellular information processing; molecular mechanisms of G protein-mediated signaling: amplification, selectivity, response kinetics and signal integration

Elliott Ros, Ph.D.
Tao Wang, Ph.D.

Assistant Professor

Research Interests: Mouse genetics, immunology, cancer genomics, imaging analysis

Tao Wang, Ph.D.
Guanghua Xiao, Ph.D.

Professor

Research Interests: Improving treatments for cancer by applying computer science and statistical methodologies to analyzing high-throughput biological data. New models and tools are currently in development to assist the investigation of disease mechanisms and their related diagnostic innovations.

Guanghua Xiao, Ph.D.
Yang Xie, Ph.D.

Professor

Research Interests: Biostatistics, bioinformatics, statistical genomics, clinical trial design, and biomarker studies

Yang Xie, Ph.D.
Chao Xing, Ph.D.

Associate Professor

Research Interests: Statistical genetics, genetic epidemiology, bioinformatics, gene mapping for complex traits

Chao Xing, Ph.D.
Xiaowei Zhan, Ph.D.

Assistant Professor

Research Interests: Statistical genetics, forward genetics screening, statistical computation, next-generation sequencing, genetic association studies

Xiaowei Zhan, Ph.D.
Jian Zhou, Ph.D.

Assistant Professor

Research Interests: Machine Learning and Statistical Methods for Genomics, Sequence Basis of Genome Regulation, Statistical Methods for Single-cell Data Analysis, The Evolution of Noncoding Genome.

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Associate Members

These faculty members do not accept graduate students. They participate in teaching, co-mentoring, exam and dissertation committees, and all other program responsibilities.

Dominika Borek, Ph.D.

Associate Professor

Research Interests: Development of methods to study heteroplasmy and the somatic evolution of cancers.

Dominika Borek, Ph.D.
Murat Cobanoglu, Ph.D.

Assistant Professor

Research Interests: Active machine learning driven cancer drug discovery

Murat Cobanoglu, Ph.D.
Dan Heitjan, Ph.D.

Professor

Research Interests: Clinical trial design and analysis; health economics; incomplete data; statistical modeling

Daniel Heitjan, Ph.D.
Julia Kozlitina, Ph.D.

Associate Professor

Research Interests: Statistics, statistical genetics, genetic epidemiology, genome-wide association studies

Julia Kozlitina, Ph.D.