Research at the O’Donnell Brain Institute
Neuroscience is entering a new era of innovation – where fundamental discoveries can transform basic and translational research. Ultimately, these discoveries will expand the potential to treat and prevent brain, spine, nerve, and muscle disorders. The Peter O’Donnell Jr. Brain Institute is focused on establishing a new research paradigm built on scientific rigor, interdisciplinary collaboration, and open innovation to accelerate advances in science and technology.
With international leaders in science, including Nobel laureates, teams affiliated with UT Southwestern’s Brain Institute are leading advances in research. This includes transformative programs in neurodegeneration, neuromodulation, neurorepair, and neuro-oncology. By building on new imaging technologies, research breakthroughs related to the mechanisms of brain disease, and the ability to analyze massive amounts of data, we are advancing discoveries in these areas and many others.
Our teams are involved in more than 500 studies. This sampling provides a snapshot of the work underway within Departments and Centers related to the O’Donnell Brain Institute:
- The Department of Neuroscience focuses on neuronal and brain functions as they relate to health and diseases.
- The Hamon Center for Regenerative Science and Medicine (CRSM) aims to improve human health by applying discoveries of the fundamental mechanisms of tissue formation and repair to develop strategies and medicines that enhance tissue regeneration.
- The Center for Alzheimer’s and Neurodegenerative Diseases researches potential treatments to cure or halt the progression of dementia and related disorders.
- The Department of Psychiatry conducts research and provides patient care for a full range of psychiatric conditions.
- The Texas Institute for Brain Injury and Repair promotes research and education to enhance the treatment and diagnosis of brain injuries.
- The Annette G. Strauss Center for Neuro-Oncology focuses on improving treatments and researching tumors of the central nervous system.
- The Perot Foundation Neuroscience Translational Research Center facilitates and enhances quality clinical research by providing resources for scientists, clinicians, and patients.
- The Whole Brain Microscopy Facility is dedicated to the study of traumatic brain injury and houses several high-throughput microscopes.
- The Rodent Behavior Core Facility assists investigators in all aspects of rodent behavioral testing.