Research at the O’Donnell Brain Institute

Neuroscience is entering a new era of innovation – where fundamental discoveries can transform basic and translational research. Ultimately, these discoveries will expand the potential to treat and prevent brain, spine, nerve, and muscle disorders. The Peter O’Donnell Jr. Brain Institute is focused on establishing a new research paradigm built on scientific rigor, interdisciplinary collaboration, and open innovation to accelerate advances in science and technology.

With international leaders in science, including Nobel laureates, teams affiliated with UT Southwestern’s Brain Institute are leading advances in research. This includes transformative programs in neurodegeneration, neuromodulation, neurorepair, and neuro-oncology. By building on new imaging technologies, research breakthroughs related to the mechanisms of brain disease, and the ability to analyze massive amounts of data, we are advancing discoveries in these areas and many others.

Our teams are involved in more than 500 studies. This sampling provides a snapshot of the work underway within Departments and Centers related to the O’Donnell Brain Institute: