O'Donnell Brain Institute Faculty

Center for Alzheimer's and Neurodegenerative Diseases (CAND)

CAND's focus is to uncover basic mechanisms of disease through rigorous science, and to use this information to develop the next generation of diagnostics and therapeutics. This has already resulted in new tools to improve drug discovery, an analysis of pathology, and a drug that is in Phase II clinical trials for Alzheimer’s. The Center, led by Dr. Marc Diamond, supports faculty, postdocs, and students across a range of disciplines. They work together to make discoveries as rapidly as possible, based on protein structure, biochemistry and cell biology, animal models, and human tissues. 

Neurological Surgery

Faculty in the Department of Neurological Surgery treat some of the most complex, difficult cases in the country including serious stroke, threatened stroke, and arteriovenous malformations. Our cerebrovascular program handles more cases and performs more procedures than any other program in the region. In addition, we are dedicated to educating future neurosurgeons for careers in academic medicine or private practice. Emphasis is on a practical, patient-centered approach to the field with expert technical training. 

Neurology and Neurotherapeutics

Neurology at UT Southwestern is a recognized leader in the comprehensive management of neurological disorders. We offer access to the latest innovative treatments in one of the most rapidly advancing fields of medicine. Our team of neurology experts include specialists in virtually every aspect of neurologic disease. We are committed to providing a dynamic and progressive environment for our residents and fellows and offer the only neurology residency program in the region. UT Southwestern is the major tertiary referral center for neurological disorders in the region making it an ideal training ground. Our department conducts multiple clinical trials and has a large and active group of researchers investigating problems such as autism, Alzheimer’s disease, and stroke.


Our faculty conduct basic research in a vibrant, interdisciplinary, and highly collaborative research community. Our tradition in metabolism and genetics, pharmacology, chemistry, biochemistry, structural biology, and biophysics provides a unique and rich environment for understanding brain function at a mechanistic level. It has become clear that significant progress in understanding disease is derived from insight into the normal functions of biological processes, and that basic research into the fundamental properties of a biological system and its perturbations in disease is the best approach to discover and develop new diagnostic and therapeutic methods.

Pediatric Neurology

Led by Chief of Neurology, Berge Minassian, M.D., pediatric neurology at UT Southwestern and Children's Health offers a range of world-class programs, providing the highest level of care to children with conditions across the neurological and developmental spectrum. From our nationally recognized Epilepsy Center to transformative research in spinal cord disorders, our expertise is improving the lives of our patients and their families.

Physical Medicine and Rehabilitation

Our mission is to optimize quality of life through excellence and innovation in patient care, research, and education. We focus on non-surgical diagnosis and management of conditions to improve our patients’ mobility and lessen difficulties in cognition and communication. We provide comprehensive rehabilitative care across the continuum, including acute hospital inpatient care, inpatient rehabilitation, outpatient rehabilitation, clinic services, and telehealth. Our outstanding faculty and staff are also committed to training tomorrow’s physiatrists in clinical and basic science research on the diagnosis, treatment, and prevention of disabilities in the areas of brain injury, pain, burn injury, multiple sclerosis, spinal cord injury, stroke, and electrodiagnostic medicine. 


Our faculty have expertise in virtually all areas pertinent to modern psychiatric practice, ranging from psychoanalysis to neurobiology to psychiatric epidemiology. This includes areas rarely found in psychiatry departments, such as medical ethics, health economics, family systems studies, psychotherapy research, neurogenesis, and psychoneuroendocrinology. We provide patient care at UT Southwestern University Hospitals, Parkland Memorial HospitalDallas Veterans Affairs Medical CenterChildren's Medical CenterPresbyterian Hospital Dallas, and Terrell State Hospital. Outpatient and specialty clinics extend our services to the community. We also collaborate with several local community agencies to provide care for the greater Dallas/Fort Worth area. Our faculty also train medical students, residents, fellows, and clinical psychology students to participate in patient care that provides the full range of psychiatric diagnoses. 


Our faculty provide world-class neuroimaging capabilities and expertise to the community and region. Our vibrant group of neuroradiologists demonstrate excellence in patient care, teaching and research using state-of-the-art imaging tools and cutting-edge approaches. We have internationally recognized expertise in functional MRI, perfusion imaging including arterial spin label MRI, diffusion tensor imaging, and complex spine and neuro-interventional procedures. Our outstanding fellowship program trains the future leaders in neuroimaging.