CSB Seminar - Dr. Ran Kafri

Please join us for the final seminar in the Spring 2017 CSB Seminar Series, next Monday, May 22, at 11 a.m. ‐ noon in ND11.218. A meet-the-speaker lunch will follow each seminar in the ND11 atrium.

Ran Kafri, Ph.D.
University of Toronto
Monday, May 22, 11 a.m.

How do animal cells sense their size? Evidence and mechanisms of size sensing.

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Dr. Ran Kafri is Assistant Professor of Molecular Genetics at the University of Toronto. The Kafri lab is dedicated to exploring the question of how signal transduction speci­es quantitative phenotypes in the context of cell size, fate determination and pharmacology. Kafri was the ­first to de­finitively show that animal cells do have cell size checkpoints (Nature 2013). The lab has now begun to identify the molecular mechanisms of size sensing. It is now shown that information on cell size is communicated, by specifi­c pathways including the p38 MAPK and LKB1, to regulate both the length of cell cycle (G1) and the rate of cell growth.