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| Sleep deprived, but still alert? Thank this molecule |
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Dr. Robert Greene
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Sleep experts know that the mental clarity lost because of a few sleepless nights can often be restored with a good night’s rest. Now, UT Southwestern researchers have identified a key molecular mechanism that regulates the brain’s ability to mentally compensate for sleep deprivation. Working with mice, they found that a molecule called an adenosine receptor is necessary for sleep-restricted animals to attain adequate levels of slow-wave activity in the brain once normal sleep resumes. It is this increase in slow-wave activity, or SWA, during rebound sleep that helps restore normal working memory and attention skills to the sleep-deprived, the scientists report in the Feb. 4 issue of the Journal of Neuroscience. Read More
Key step in bicarbonate secretion might lead to novel cystic fibrosis treatments*
Researchers at UT Southwestern have uncovered the underlying mechanism in the body that coordinates the secretion of bicarbonate — also known as baking soda — from the pancreas and other organs, a process that is essential for dissolving digestive enzymes and mucus proteins and for neutralizing stomach acids. Read More
Scientists identify compound that may liberate cholesterol
Researchers at UT Southwestern have identified in mice a compound that liberates cholesterol that has inappropriately accumulated to excessive levels inside cells. Read More
Bacterial protein gives Lyme disease its bite
UT Southwestern researchers' findings suggest that the bacterial protein, which aids in transporting the metal manganese, is essential for the bacterium that causes Lyme disease to become virulent. Read More
Researchers weigh anomaly of liver fat in low-body-fat patients
Researchers at UT Southwestern have uncovered crucial clues about a paradoxical disease in which patients with no body fat develop many of the health complications usually found in obese people. Read More
Research Studies
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