The MoD curriculum will be superimposed on that of the existing Integrative Biology (IB) Ph.D. program. Students are required to take the Core Course and complete three basic science laboratory rotations during the first year. During the second and third year, students will take a specific combination of courses offered by both the Division of Basic Science and the Division of Clinical Science (defined below), do clinical research and medical clerkships, and attend selected clinical conferences. The additional coursework, clerkships and directed self-learning components will add approximately six months to the time to degree. There will be some flexibility in the curriculum design and the graduate student advisors will work with the students to customize their coursework according to their research interest and prior training.
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| Required Coursework |
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First Year Core Curriculum (18 credits) - required
- Core Course - required, fall and spring of 1st year (15 credits)
- 3 Laboratory rotations (3 credits)
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Health and Disease Modules (4.5 credits) - required
- Integrated Human Physiology. IB new course; 1.5 credits, summer 1st/2nd year. Selected physiological systems will be discussed and integrated with principles at the cellular and molecular levels.
- Human Biology and Disease. IB 5301; 3 credits, fall of 2nd year.
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Clinical and Translation Research Modules (4.0 credits) - required
- Clinical Research Questions & Methods. DCS 5103; 1 credit, summer 1st/2nd year. This course introduces students to the process in defining and developing a clinical research question.
- Case Studies in Clinical and Translational Research. DCS new course; in development; 1.5 credits. Most likely fall or spring of 2nd year.
- Clinical research clerkship. DCS new course; 1.5 credits; 1 month, preferably summer between 1st/2nd year or in case of schedule conflicts, fall of 2nd year. Students will learn how medical principles are integrated into clinical research. They will develop an understanding of the scientific and clinical background, research question and research protocols.
- Ethics in Clinical Science. DCS 5105; fall or spring of 3rd year. Audit 6 core sessions on treatment vs. research, informed consent, mentorship, conflicts of interest, misconduct/responsible research, authorship/data ownership.
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Bedside to Bench Clinical Clerkship Module (1 credit) - required
First-hand clinical experience will introduce students to the language of medicine and the nature of the clinical interactions that are central to the management of patients and to the conduct of clinical or translational research. Students will have a focused mentored clinical experience led by physician-scientists who are involved in both patient care and research. The clerkship will encompass two weeks of hospital-based experiences such as participation in Attending Rounds. In some cases, students may also elect to observe in a series of outpatient clinics that are directly related to their research interest.
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| Elective Coursework (3 credits required) |
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At least 3 credits of advanced course electives are required and usually taken in the spring of the 1st year.
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Examples of highly recommended electives include:
- Experimental Approaches to Complex Genetic Diseases & Gene Therapy (BSCI 5112; 1.5 credits)
- Molecular Basis of Metabolic Regulation (BSCI 5122; 1.5 credits)
- Fundamentals of Neuroscience (NS 5096; 3 credits)
- Cancer Biology (BSCI 5152; 1.5 credits)
- Statistics (BSCI new course; 1.5 credits)
- Advanced Genetics II. Human Genetics II (GD5141; 1.5 credits)
- Fundamentals of Immunology (IMM5173; 1.5 credits)
- Immunology of Infectious Disease (BSCI 5101; 1.5 credits)
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Sample Timeline for MoD Students’ First Three Years in Graduate Training
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Year
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Summer
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Fall
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Spring
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1st
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- Core Course
- 2 lab rotations
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- Core Course
- Adv. Courses (3 credits)
- 1 lab rotation
- Apply to MoD Track
- Select dissertation project/mentor
- Select IB Program
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2nd
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b/t 1st and 2nd year
- Integrated Human Physiology
(IB new; 1.5 credits)
- DCS5103 Clin. Res. Ques. & Methods
(1 credit)
- DCS Clinical Research Clerkship
(1 month; 1.5 credits)
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- IB5301 Hu. Biol & Dis. (3 credits)
- Dissertation research
- JCs & WIPs
- DCS Case Studies in Clin.& Transl. Res
(1.5 credit)
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- Dissertation research
- JCs & WIPs
- Qualifying exam
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3rd
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- DCS new Bench/Bedside clinical clerkship either summer/fall/spring
(1 credit)
- Dissertation research
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- DCS5101 Ethics in Clin. Sci.
- JCs & WIPs
- Dissertation research
- 1st Dissertation Com. Mtg.
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- Dissertation research
- JCs & WIPs
- 2nd Dissertation Com. Mtg.
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Journal Club
Students are required to attend disease-oriented journal clubs in the Integrative Biology program. Students are also encouraged to gain more insight into the clinical aspects of the disease focus of the journal clubs by attending appropriate clinical conferences and medical grand rounds with MSTP students.
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WIPs
Students are required to attend Integrative Biology Student Works-in-Progress seminars (WIPS) and selected DCS Trainee WIPs. Meets on Mondays, 12pm, ND13.218.
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Seminars
Attend selected basic science and clinical science seminars (such as DCS Frontiers in Experimental Design & Clinical Science Forum) and University Lectures.
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