Computational and Systems Biology Faculty

Steven Altschuler, PhD (UC San Diego, Mathematics) Design principles underlying the spatial-temporal organization of molecular networks.

Leon Avery, PhD (Stanford University, Biochemistry) Study of feeding in the nematode Caenorhabditis elegans. Particularly interested in quantitative models of behavioral strategies.

Johann Deisenhofer, PhD (Technical University of Munich, Physics) Structural biology, membrane proteins, protein stability and function.

Christian Forst, PhD (University of Vienna, Theoretical Chemistry) Research in computational systems biology. Interested in host-pathogen interactions, drug response, drug development and emergence of infectious diseases as well as metagenomicanalysis and multi-level biosystems comparisons.

Kevin Gardner, PhD (Yale University, Molecular Biophysics and Biochemistry) Biophysical and biochemical studies of photoreceptors and other signaling proteins.

Harold R. (Skip) Garner, Ph.D (University of Wisconsin, Plasma Physics) Automation and instrumentation for genomics research; DNA sequence analysis; computational biology.

Nick Grishin, PhD (UT Southwestern, Molecular Biophysics) Computational biology; analysis of protein sequences and structures.

Robin Hiesinger, PhD (University of Freiburg) Neurogenetics. Brain wiring, synaptic specification and function in Drosophila. Computational approach to 4D visualization.

Zbyszek Otwinowski, PhD, (University of Chicago, Biochemistry) Three-dimensional structures of biological molecules.

Alexander Pertsemlidis, PhD (UC Berkeley, Biophysics) MicroRNA regulation of lung cancer pathogenesis; genetic determinants of cardiovascular disease.

Rama Ranganathan, MD, PhD (UC San Diego, Biology) Structural basis for signal processing in Drosophila photoreceptors.

Luke Rice, PhD (Yale University, Molecular Biophysics and Biochemistry) Integrating structure, kinetics, and computation to understand the molecular determinants and regulatory mechanisms of microtubule dynamics.

Michael Rosen, PhD (Harvard University, Organic Chemistry) Study directed toward understanding the structural, biochemical and cell biological mechanisms of cytoskeletal regulation by the Rho GTPases. The long term objective is to quantitatively understand how the cytoskeleton integrates biological inputs to create complex but coherent outputs.

Elliott Ross, PhD (Cornell University, Biochemistry) Mechanisms of G-protein signaling; amplification, selectivity, response timing; structure/function of GTPase-activating proteins and associated receptors.

Richard Scheuermann, PhD (UC Berkley, Molecular Biology) Bioinformatics and computational biology as data mining tools allowing hypothesis development based on large data sets; testing these hypotheses using directed wet lab experimentation.

Gürol Süel, PhD (UT Southwestern, Molecular Biophysics) Functional role of biochemical "noise" in cellular differentiation.

Marc Turcotte, PhD (McGill University, Physics) Systems biology modeling and simulation; complex systems (nonlinear dynamics); graph, network and control theory.

Lani Wu, PhD (UC San Diego, Mathematics) Design principles underlying the formation of cellular polarity.

Xian-Jin Xie, PhD (University of Iowa, Biostatistics) Model diagnosis and goodness-of-fit tests; survival analysis and categorical data analysis; methods on correlated data.

Yang Xie, PhD -- Processing and analysis of high throughput data; false discovery rate estimation; integrated analysis methodology; Bayesian analysis methodology; design and analysis of clinical trials.

Chin-Rang Yang, PhD (University of Wisconsin, Human Oncology and Developmental Biology) Computational reconstruction of biological networks; in silico biology; biological data mining.