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Program Chair: Nicolai S. C. van Oers
Kiyoshi Ariizumi -- Molecular mechanisms for the pathogenesis of skin diseases.
Michael Bennett -- Immunogenetics and immunobiology of marrow-cell grafts; differentiation and function of NK cells; graft-versus-host reactions; natural immunity to infection; tumor immunology.
Zhijian (James) Chen -- Ubiquitin-proteasome pathway; NF-kappaß signaling; innate immunity; T cell receptor signaling.
Peter Chen -- Epigenetic gene regulation in an immune privileged environment; ocular
immunology; tumor immunosurveillance.
Laurie S. Davis -- T-cell activation; autoimmunity; cytokine regulation.
Todd Eagar -- Regulation of T cell activation and differentiation, Therapeutic control of autoimmune disease.
Pila Estess -- Molecular immunology; structure/function relationships in lymphocyte cell-surface antigens, including CD44 and lymphocyte homing receptors; role of these molecules in autoimmune diseases and inflammation; molecular pathology.
J. David Farrar -- Molecular immunology; signal transduction; regulation of T-cell differentiation and cytokine gene expression.
James Forman -- T-cell recognition of major histocompatibility complex molecules; nonclassical class I molecules; NK cells.
Michelle Joubert Gill -- Pathogenesis and immunobiology of infectious disease; human dendritic cells in respiratory syncytial viral infections; the host mucosal immune response to respiratory viral infections in children; dendritic cells in the pathogenesis of asthma.
Michael Kyba -- Stem cell biology; developmental hematopoiesis.
J. Victor Garcia-Martinez -- Lenti virus-based vectors for human gene therapy; xenograft models of human hematopoiesis; the role of HIV and SIV Nef in HIV pathogenesis and disease progression; viral regulation of signal-transduction pathways.
William T. Garrard -- Regulation of V(D)J recombination of antibody genes; chromosome structure; control of gene expression; chromosome replication, condensation and segregation at mitosis; nuclear organization.
Rebecca S. Gruchalla -- Immunopathology of antibiotic drug allergy, specifically sulfonamide drug allergy.
Eric J. Hansen -- Microbial pathogenesis and the immune response; use of recombinant DNA methods in vaccine development.
Lora Hooper -- Host-microbial interactions; mucosal immunology.
Nitin J. Karandikar -- The role of CD4 and CD8 T cells in the pathogenesis and regulation of multiple sclerosis; mechanisms of therapeutic immunomodulation of MS; B7/CD28:CTLA-4-mediated costimulation in autoimmune demyelination; molecular characterization of T cells mediating GVH versus GVL effects in patients with leukemia; effector CTL responses in viral infections.
David R. Karp -- Function of class II molecules of the major histocompatibility complex, including antigen presentation and its role in autoimmune disease; role of complement receptors in B-cell activation and presentation of soluble antigens.
Christopher Y. H. Lu -- Transplant tolerance; regulation of macrophage function; ontogeny of macrophage function and its implications for self/nonself discrimination and autoimmunity; mechanisms of renal allograft rejection.
Kristen Lynch -- Alternative splicing; regulation of gene expression; T cell activation.
Bonnie Miller -- Mechanisms of opioid immunomodulatory effects.
Chandra Mohan -- The immunopathology and immunogenetics of lupus; immunological tolerance; autoimmunity.
Nancy Monson -- The role of B cells in the pathogensis of multiple sclerosis.
Mark E. Mummert -- Cutaneuous immunology; the role of carbohydrates in immune regulation; development of novel reagents for modifying immune response; the roles of hyaluronan in Langerhans cell biology.
Robert S. Munford -- Interactions of purified and natural Gram-negative lipopolysaccharides (LPS, endotoxins) with human cells; host mechanisms for degradation of LPS; gene therapy for inflammatory diseases.
Jerry Y. Niederkorn -- Immune privilege of the anterior chamber of the eye; immune surveillance of intraocular tumors; immune modulation of cancer metastases; immunobiology of corneal transplants; immunology of parasitic diseases.
Chandrashekhar Pasare -- Toll-like receptors and control of adaptive immunity: Dendritic cell biology
Octavio Ramilo -- Immunopathogenesis of HIV infection, with special interest in the pediatric population.
Anne B. Satterthwaite -- Genetic analysis of signal-transduction pathways regulating B lymphocyte development and function.
John Schatzle -- Natural killer cell receptor structure and function; molecular mechanisms of bone-marrow transplant rejection and tumor lysis by NK cells.
Richard H. Scheuermann -- Regulation of immunoglobulin gene expression; regulation of lymphocyte growth, development and apoptosis; lymphocyte receptor signal transduction; technology development; novel approaches to cancer therapy.
Mark H. Siegelman -- The molecular biology of cell-surface molecules governing adhesion to and transmigration through vascular endothelium.
Olaf Stuve -- Prion protein (PrP) as a disease modifier in autoimmune diseases of the central nervous system.
Nancy E. Street -- Activation and differentiation of murine T-helper cells; the role of T-helper cells in tumor dormancy and infectious disease.
Iwona Stroynowski -- Structure and function of immunologically relevant molecules; antigen presentation in the immune system.
Joel D. Taurog -- Biology of HLA and disease.
Dwain L. Thiele -- Mechanisms of cytotoxic lymphocyte function and activation; transplantation immunology.
James A. Thomas -- Signal transduction in innate immunity.
Philip E. Thorpe -- Targeting of coagulants and cytotoxic agents to the blood vessels of solid tumors as a novel approach to cancer therapy; synthesis of novel inhibitors of tumor blood-vessel growth; immunotoxins.
Jonathan W. Uhr -- Cancer immunology and genetics.
Nicolai S. C. van Oers -- Regulation of antigen-receptor signal-transduction systems.
Ellen S. Vitetta -- The development, genetic engineering , and testing of immunotoxins, antibodies, and vaccines in animals and humans. We also study the immunology of tumor dormancy, Gulf War Syndrome and multidrug resistance in tumors.
Edward K. (Ward) Wakeland -- The molecular biology of genes regulating immune responses and autoimmunity.
E. Sally Ward -- Genetic manipulation and structure/function studies of antibodies and T-cell receptors; T-cell mediated autoimmunity.
Jonathan C. Weissler -- Regulation of cytotoxic lymphocytes in human lung; accessory cell function in human lung.
Christoph Wuelfing, Ph.D. -- T-cell activation using video microscopy; costimulation and cell biology of T-cell activation.
Felix Yarovinsky -- Toll-like receptor signaling, dendritic cells, and host-pathogen interactions
Dorothy C. Yuan -- Molecular regulation of immunoglobulin synthesis; interactions between B and T lymphocytes and NK cell.
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