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Track Chair: David Mangelsdorf
Joseph Albanesi -- Mechanisms of membrane fusion; role of lipids in membrane trafficking; membrane vesiculation of dynamin.
Steven Altshuler -- Single cell perturbation analysis of cell signaling pathways.
Rolf A. Brekken -- Tumor-host interactions in pancreatic cancer.
Yuh Min Chook -- Structures and mechanisms of nuclear transport and the nuclear pore complex.
Melanie Cobb -- Protein kinase cascades; MAP kinases; signal-transduction mechanisms.
David R. Corey -- Engineering proteins and nucleic acids for novel function.
J. R. Falck -- Total synthesis of natural products; synthetic methodology; organometalics; eicosanoids; medicinal chemistry.
David L. Garbers - Molecular basis of fertilization; function of cyclic GMP as a signaling molecule.
Kevin H. Gardner -- NMR-based structural studies of proteins involved in transcriptional regulation.
Alfred Gilman -- Hormonal regulation of cyclic AMP metabolism; mechanisms of control of hormone-sensitive adenylate cyclase; regulatory GTP-binding proteins.
Joel Goodman -- Intracellular sorting of newly synthesized proteins; organelle biogenesis and membrane structure and function; the yeast peroxisome as a model of organellar assembly.
Stephen Hammes -- Analysis of nongenomic steroid signaling; progesteronemediated maturation of oocytes.
Jin Jiang -- Signal-transduction pathways in development and human disease; genetic control of organ growth and patterning; tumor suppressor genes.
Jane E. Johnson -- Molecular biology of mammalian neural development.
Steven Kliewer -- Physiology of nuclear receptors.
Mark Lehrman -- Informational carbohydrates in the endoplasmic reticulum: roles in protein folding, stress responses and human disease.
David Mangelsdorf -- Mechanism of nuclear hormone receptor action; role of retinoids in cancer; transcriptional regulation of lipid metabolism.
Timothy L. Megraw -- Structure and function of centrosomes in cell division and gametogenesis.
John Minna -- Molecular genetics of human cancer; growth factors and signal transduction in human tumors.
Marc Mumby -- Signaling pathways controlling cell growth and transformation
Keith L. Parker - Gene regulation of steroidogenic tissue differentiation; nuclear hormone receptors; hypothalamic obesity.
Margaret Phillips -- Polyamine and pyrimidine metabolism in trypanosome and malaria parasites.
Rama Ranganathan -- Structural basis for signal processing in Drosophila photoreceptors.
Jose Rizo-Rey -- Structural analysis by nuclear magnetic resonance of proteins involved in calcium-triggered synaptic vesicle exocytosis.
Michael Rosen -- Analysis of the structural, biochemical, and cell biological mechanisms that regulate the actin cytoskeleton.
Elliott Ross -- Mechanisms and regulatory behavior of G-protein signaling; regulated protein-protein interactions in signal transduction.
Dean Smith -- Sensory transduction in Drosophila melanogaster.
Paul Sternweis -- Regulation of intracellular events by cell-surface receptors; structure and function of GTP-dependent regulatory proteins and their effectors.
Ronald Taussig -- G protein-mediated signaling.
Jonathan Terman -- Axonal growth and guidance; neuronal connectivity; axonal regeneration.
Philip Thorpe -- Development of novel angiogenesis inhibitors and agents for inducing thrombosis of tumor blood vessels for cancer treatment.
Thomas Wilkie -- Signal-transduction pathways in mammalian development and energy homeostasis.
Lani Wu -- Design principles in biological networks.
Hongtao Yu -- Study of cell division cycle.
Guang Zhao -- Growth factor-mediated signal transduction in embryonic stem-cell biology, germ-cell fate determination and nuclear reprogramming.
Yingming Zhao -- Functional proteomics and mass spectrometry. |
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