Postdoctoral Training Positions Available at UT Southwestern (M-Z)

Microbiology

There are no positions available at this time. 

Department of Molecular Biology

Deciphering Molecular Mechanisms used by Bacterial Pathogens to Subvert Host Defenses (97)

A postdoctoral position is available in the laboratory of Dr. Kim Orth at UT Southwestern Medical School. The Orth lab is interested in deciphering molecular mechanisms used by bacterial pathogens to manipulate the host signaling pathways during infection. By understanding the activity of individual virulence factors that are secreted by type III secretion systems, we will be able to understand the multifaceted approach used by the bacteria during infection. As demonstrated by our past discoveries, we elucidate both the host cell targets for the bacterial effectors and the bacterial effector’s molecular activity using a variety of biochemical, genetic and microbiology techniques.

Details on our research interests and past publications can be found at http://www4.utsouthwestern.edu/orthlab/.

The candidate should be self-motivated with a long-term interest in academic science. Expertise in molecular microbial pathogenesis is preferred, but not required. Salary will be competitive and commensurate with experience. Please send curriculum vitae and contact information for three references to:

Kim Orth, PhD
Department of Molecular Biology
UT Southwestern Medical Center
6000 Harry Hines Blvd
Dallas, Texas 75390-9148
Kim.orth@utsouthwestern.edu

Genetic and Epigenetic Regulation of Adult Neural Stem Cells and Their Role in Regeneration, Aging, and Cancer (79)
A postdoctoral position is available in the laboratory of Dr. Chun-Li Zhang at UT Southwestern. The major interest of this laboratory is to elucidate the molecular and cellular mechanism regulating brain function with a focus on adult neural stem cells and epigenetics. Combinations of techniques in molecular and cell biology, biochemistry, mouse genetics and behavior will be employed. Detailed research interests and related publications can be found at: http://www.utsouthwestern.edu/findfac/research/0,2357,29691,00.html

Self-motivated individuals with a Ph.D. and/or a M.D. degree are encouraged to apply. Candidates with demonstrated records in molecular or developmental biology, biochemistry or neuroscience are preferred. The candidate is expected to work in a collaborative environment. Salary will be competitive and commensurate with experience.  Please send curriculum vitae, description of research background and interests and contact information of three references to: 

Chun-Li Zhang, Ph.D.
Department of Molecular Biology
UT Southwestern Medical Center
6000 Harry Hines Blvd.
Dallas, TX 75390-9148.
Email: Chun-Li.Zhang@utsouthwestern.edu

UT Southwestern is an Equal Opportunity/Affirmative Action Employer.

 Department of Neurology  

Cell Signaling and Cancer (111)

A NIH-funded postdoctoral training position is immediately available to study signal transduction in cancer at the Department of Neurology, University of Texas Southwestern Medical Center.   Our laboratory focuses on two major areas of research.  1) Receptor tyrosine kinase signaling in cancer and 2) how inflammatory signaling networks influence oncogenic signaling pathways.  We are particularly interested in the biology of glioma and use an approach combining cell culture, mouse models and translational studies using human glioma tissue.   Please refer to our recent publications for further information (EMBO Reports 9(8):766-73. 2008, Cancer Research 69:2809-2816, 2009, Cancer Research 69, 4107-4111.  2009). The laboratory is located at the Dallas VA Medical Center, a major teaching hospital of UT Southwestern. 

We are looking for an individual with a PhD and/or MD degree, who is highly motivated with experience in molecular and cellular biology and some evidence of research accomplishment.  Experience in working with mice is strongly preferred.  Our laboratory is rapidly growing and offers the opportunity to conduct high quality research in a supportive environment.

Please send your CV, a statement of research interests, and the names of three references to Amyn.Habib@UTSouthwestern.edu. 

Genetic Animal Models of Autism (88)

A postdoctoral training position is immediately available to study genetic animal models of autism and autism spectrum disorders.  Potential projects include behavioral, cellular, and molecular characterization of genetic animal models relevant to autism and autism spectrum disorder.

Candidates should have a Ph.D., M.D./Ph.D., M.D. or equivalent in neuroscience, biochemistry, molecular biology, physiology, or psychology.  Experience with behavioral analysis, knockout technology or general neuroscience background is desired but not required.  This is an excellent opportunity for a behavioral person to gain molecular training, for a molecular person to gain behavioral training, or for an electrophysiologist to broaden their horizons in a rapidly growing, highly fundable area of disease-related, translational research.  The trainee should be able to work independently, communicate effectively, and to be willing to fully participate in collaborative opportunities at the University of Texas Southwestern Medical Center in Dallas. Salary/benefits are competitive with industry standards and commensurate with experience.

Send CV, description of research background and interests, and names of
two references to:

Craig M. Powell, M.D., Ph.D.
Assistant Professor
Depts. of Neurology and Psychiatry
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8813

UT Southwestern is an Equal Opportunity/Affirmative Action Employer 

Neuroscience

Molecular Control of Neural Development and Cancer (90)

A postdoctoral position is available in the laboratory of Dr. Jane E. Johnson for a self-motivated individual pursuing a career in Academia who is interested in transcription factor function, development of the nervous system, and/or cancers of neural origin.

The research in the Johnson lab is focused on vertebrate nervous system development during the transition from proliferating neural stem cells to differentiating neurons and glia. These studies involve understanding the regulation and function of the neural specific class of bHLH transcription factors. Alteration in function and expression of these factors results in disturbances of connectivity, imbalances in excitatory and inhibitory neuron formation, and loss of control of neural cell number. Our goals are to uncover processes initiating neural stem/progenitor cell differentiation, and to generate new models to study the molecular control of neural differentiation and specification throughout the nervous system. To attain these goals, we generate and utilize transgenic and mutant mouse models while using biochemistry, molecular biology, and genome wide efforts in transcription factor target identity to uncover novel regulatory mechanisms controlling neural development.

A summary of our research and related publications can be found at http://www8.utsouthwestern.edu/utsw/cda/dept120915/files/150735.html

Successful candidates must have a Ph.D. degree, peer reviewed publications, and a strong background in one or more of the following areas: biochemistry, molecular biology, developmental biology, transcription factor biology and bioinformatics.

To apply please send by email:

1. A statement of interest explaining the reasons why the candidate is interested in the position and how the position might further the candidate’s career goals.

2. A CV.

3. Names and contact information for 3 professional references.

Jane E. Johnson, Ph.D.
Professor, Neuroscience
5323 Harry Hines Blvd.
Dallas, TX 75390-9111
Jane.Johnson@utsouthwestern.edu

UT Southwestern is an Equal Opportunity/Affirmative Action Employer.

Department of Ophthalmology

Angiogenesis and vascular retinopathy (106)

A postdoctoral position is available immediately in the laboratory of Dr. Shusheng Wang, Department of Ophthalmology, at the University of Texas Southwestern Medical Center at Dallas. The lab is focused on understanding how angiogenesis is regulated at the transcriptional and post-trancriptional levels, and finding a novel therapeutic solution to vascular retinopathy. Current projects involve studying the role of microRNAs in angiogenesis and vascular diseases using mouse genetic models.
   

Candidates must have a Ph.D. or M.D. degree, and a record of scientific accomplishment. Prior experience in molecular biology is essential and experience in retinal disease is highly desirable. Please send CV, statement of research interests, and the names of three referees to:

Shusheng Wang, Ph.D.
Assistant Professor
Department of Ophthalmology
UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, TX 75390-9057
Phone:  214-648-4732
Fax:  214-648-9061
Email: shusheng.wang@utsouthwestern.edu
Lab Website: http://www4.utsouthwestern.edu/wanglab

Department of Pathology 

Adhesion Receptor Function in T Cell Regulation and Autoimmunity (83)

A post-doctoral position studying the role of lymphocyte adhesion molecules in the regulation of inflammatory bowel disease is available in the laboratory of Dr. Mark H. Siegelman, Departments of Pathology and Immunology. Candidates should have a recent Ph.D. or M.D. with a strong research background in cellular immunology, immune regulation, and autoimmune disease. Specific experience in murine models of autoimmunity or human autoimmune disease is highly desirable, as is experience with multi-color flow cytometry, lymphocyte function analyses, and molecular biology. Ongoing studies will use both cellular and molecular methods to characterize adhesion molecules as markers of regulatory T cells and their application to the control of human autoimmune disease and mouse models thereof (Blood 107: 619-627).

Qualified candidates should send a current Curriculum Vitae describing their research background along with three (3) letters of reference to:

Mark Siegelman, M.D., Ph.D.
Department of Pathology MC9072
UT Southwestern Medical Center at Dallas
5323 Harry Hines Blvd.
Dallas, TX  75390-9072
mark.siegelman@utsouthwestern.edu 

Adhesion Receptor Function in T Cell Regulation and Transplantation (84)

A postdoctoral position studying the role of lymphocyte adhesion molecules in the regulation of immune-mediated organ transplant rejection is available in the laboratory of Dr. Mark H. Siegelman, Departments of Pathology and Immunology. Candidates should have a recent Ph.D. or M.D. with a strong research background in cellular immunology and immune regulation. Specific experience in murine models of immunity or human autoimmune disease is highly desirable, as is experience with multi-color flow cytometry, lymphocyte function analyses, and molecular biology. Ongoing studies will use both cellular and molecular methods to characterize adhesion molecules as markers of regulatory T cells and their application to the control of organ transplant rejection and mouse models thereof (Blood 107: 619-627).

Qualified candidates should send a current Curriculum Vitae describing their research background along with three (3) letters of reference to:

Mark Siegelman, M.D., Ph.D.
Department of Pathology MC9072
UT Southwestern Medical Center at Dallas
5323 Harry Hines Blvd.
Dallas, TX  75390-9072
mark.siegelman@utsouthwestern.edu 

UT Southwestern is an Equal Opportunity/Affirmative Action Employer

Department of Pharmacology

Tumor Angiogenesis (102)

A postdoctoral position is available immediately in the laboratory of Dr. Philip Thorpe in the Department of Pharmacology.

The applicant will develop new therapies that target and destroy tumor blood vessels.  The work will involve studies of immunological mechanisms of tumor vessel destruction and efficacy studies in rodent models. The successful candidate will hold a Ph.D. or equivalent degree in immunology, antibody technology, pharmacology, or related field.  Experience of animal models would be an advantage.  The candidate must be self motivated, possess strong problem solving and critical thinking skills and be capable of working with minimal supervision in a collaborative setting.

Please provide curriculum vitae, a brief summary of research experience, names and contact information for references to:

Dr. Philip Thorpe
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9041
email: Linda.Watkins@utsouthwestern.edu

Broad Spectrum Antibody-based Antiviral Agents (96)

A postdoctoral position is available immediately in the laboratory of Dr. Philip Thorpe in the Department of Pharmacology.

The applicant will develop novel antibody-based antiviral agents for the treatment of hemorrhagic fever viruses.  The project will involve in vitro studies of antibody binding to virions and infected cells, efficacy studies in rodent models and analyses of mechanisms. The successful candidate will hold a Ph.D. or equivalent degree in virology, immunology, antibody technology, pharmacology, or related field.  Experience of animal models would be an advantage.  The candidate must be self motivated, possess strong problem solving and critical thinking skills and be capable of working with minimal supervision in a collaborative setting.

Please provide curriculum vitae, a brief summary of research experience, names and contact information for references to:

Philip Thorpe
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9041
Linda.Watkins@utsouthwestern.edu.

Biology and Application of Spermatogonial Stem Cells (92)

Two NIH funded Postdoctoral Positions are now available to perform research on the Biology and Application of Spermatogonial Stem Cells at the University of Texas Southwestern Medical Center in Dallas

Each position holds the unique opportunity for trainees to master key elements of animal genetics, physiology, cellular biology, developmental biology, biochemistry and biotechnology as they apply state-of-the-art techniques to achieve their research aims.  Applicants are required to have a Ph.D. in an area of biological sciences, and to have a strong scientific interest in stem cell biology, germ cell development, germline epigenetics and/or reproductive physiology.  Candidates demonstrating published working experience in areas of stem cell culture, primary cell culture, fluorescence microscopy, microarray analyses and animal surgery would possess the preferred professional skills.

Interested candidates should send PDF files containing their C.V., up to 3 references, and a recent publication by email to:

Ruby.Drye@utsouthwestern.edu 

(Please keep total file size under 3 MB when sent by email)

Or

Send hard copies of application materials by mail to: 

Dr. F. Kent Hamra
Department of Pharmacology
Cecil H. & Ida Green Center for
  Reproductive Biology Sciences
UT Southwestern Medical Center
6001 Forest Park Road
Dallas, Texas 75390-9051

Applications will be accepted through November 2009

Excitable Gene Regulatory Circuits (87)

A full-time postdoctoral researcher position in computational biology is expected to be available soon in Dr. Marc Turcotte’s Quantitative & Computational Biology Group. In this project, the successful researcher will focus on using analytical and computational approaches to systematically study the dynamical properties of candidate excitable gene regulatory circuits enabling competence in the bacterium Bacillus subtilis. Competence is a cellular state of the bacterium during which it can incorporate exogenous DNA into its genome. Specifically, you will model and simulate both the continuous and discrete (stochastic) versions of excitable (and other) gene regulatory circuits, in order to provide a global and detailed view of how biochemical noise redistributes as a function of circuit topology in candidate networks. You will look for possible conservation laws. This computational survey of topologies is expected to shed light on how evolution might be harnessing biochemical noise as an evolutionary handle.

This research will require a Ph.D. in mathematics, physics, electrical engineering, computer science, or a closely related field. More specifically, you will need experience in nonlinear dynamical systems theory, bifurcation theory, ordinary differential equations, stochastics, statistics and optimization. Above all, you will need to demonstrate a passion for elucidating fundamental problems in biology using mathematical and computational approaches.

Fluency in Matlab and a strong knowledge of Mathematica are among the required skills. Excellent UNIX skills are expected. Parallel computations will be performed at UTSW on an in-house UNIX cluster (Green Center for Systems Biology) and/or remotely, using the extensive computational facilities at the Texas Advanced Computer Center (TACC).

Interested individuals should immediately submit via email, a concise one-page description of research interests, short-term and long-term plans, a C.V., and contact information (including phone numbers) for three references to:

Dr. Marc Turcotte, Ph.D.
Marc.Turcotte@utsouthwestern.edu
www4.utsouthwestern.edu/turcottelab

Department of Pharmacology/Recruitment
The University of Texas Southwestern Medical Center
6001 Forest Park Rd.
Dallas, Texas  75390-904l

Systems Biology (77)

A full-time postdoctoral position is available in the Altschuler & Wu laboratory.

Our lab investigates the dynamics of signaling networks in mammalian cell systems using a combination of experimental and computational approaches (http://www4.utsouthwestern.edu/altschulerwulab/). 

Applicants should have (or be about to receive) a Ph.D. in biology, biochemistry, or other closely related fields. Candidates with strong interests in quantitative biology and experience in fluorescence microscopy are preferred.

Applicants should submit a brief one-page description of research interests and plans, a resume, and contact information for three references to Dr. Lani Wu (Lani.Wu@utsouthwestern.edu)

Cancer Biology (76)

A full-time cancer biology postdoctoral position is available in the Altschuler & Wu laboratory.

The successful candidate will investigate cellular heterogeneity in cancer using model cell line systems and histology. The lab is highly multi-disciplinary and the successful candidate will have the opportunity to work side-by-side with computational biologists. (http://www4.utsouthwestern.edu/altschulerwulab/). 

Applicants should have (or be about to receive) a Ph.D. in biology, biochemistry, or other closely related fields. Candidates with a strong background in cancer biology, immunofluorescence microscopy, and cell signaling are preferred.

Applicants should submit a brief one-page description of research interests and plans, a resume, and contact information for three references to Dr. Lani Wu (Lani.Wu@utsouthwestern.edu)

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer

Department of Surgery 

Training in Trauma, Inflammation, Sepsis and Critical Care (108)

Three NIH-funded postdoctoral training positions are available July 1, 2010 for 12 month appointments.  MDs or PhDs from accredited medical or graduate schools who are interested in developing investigative techniques to examine mechanisms by which traumatic injury, sepsis, and inflammation alter downstream organ function are eligible.  MDs must have completed a minimum of two years of residency in surgery, pediatrics or anesthesia. 

Candidates should send their CV, a statement of goals and expectations and two references by January 2, 2010 to:

Fiemu Nwariaku, M.D.
Program Director
UT  Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, Texas 75390-9156
Office:  214-648-7200
Email:  joy.lilljedahl@utsouthwestern.edu

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer

Department of Urology

There are no positions available at this time. 

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer