Advanced Imaging Research Center
There are no available positions at this time.
UT Southwestern is an Equal Opportunity/Affirmative Action Employer
Department of Biochemistry
Biochemical Mechanisms of RNA Interference (RNAi) (107)
A Postdoctoral position is available in the laboratory of Dr. Qinghua Liu at the Department of Biochemistry, UT Southwestern Medical Center at Dallas, USA.
Candidates require a Ph.D with a strong background in the field of Biochemistry and Molecular Biology. The primary focus of research includes: 1) Biochemical studies of the Drosophila and human RNA-induced silencing complex (RISC), the catalytic engine of RNAi. 2) Regulatory mechanisms of miRNA biogenesis and effector functions. These research topics will be addressed using a classic biochemical fractionation and reconstitution approach. For preliminary data, please refer to our recent publications:
Science (2009) 325:750-3; Cell (2009) 139: 112-22 and to our website:
http://www.utsouthwestern.edu/findfac/research/0,2357,50723,00.html.
Please email you CV and contact information for three references to:
Qinghua Liu, Ph.D.
Assistant Professor
Department of Biochemistry
email: qinghua.liu@utsouthwestern.edu
UT Southwestern is an Equal Opportunity, Affirmative Action Employer
Harold C. Simmons Comprehensive Cancer Center 
Transcriptional Regulation (109)
Research Area: Transcription, Chromatin, Gene Regulation, Posttranslational Modification, and Molecular Virology
Description of project: A postdoctoral position is available to study mechanisms of chromatin-dependent transcription and posttranslational modification of transcription factors, cofactors and the general transcription machinery. In vitro-reconstituted chromatin transcription systems are frequently used in the lab to identify factors and pathways leading to gene activation and repression. Current focuses include functional interplays between AP-1, C/EBP, YY1, p53, and HPV-encoded E2 and E6 proteins. Several cellular chromatin adaptors, including Brd4, are also studied to define their roles in mediating cellular and viral gene expression.
Applicants with a Ph.D. degree and a strong background in protein biochemistry, molecular biology and virology are encouraged to apply.
Please forward your CV and names of three referees to:
Dr. Cheng-Ming Chiang
Simmons Comprehensive Cancer Center
UT Southwestern Medical Center
5323 Harry Hines Blvd., ND2.210H
Dallas, Texas 75390-8807
Phone: (214) 645-6128
Fax: (214) 645-6347
E-mail: Cheng-Ming.Chiang@UTSouthwestern.edu
Website: http://www.utsouthwestern.edu/findfac/research/0,2357,95126,00.html
Molecular Mechanisms of Tumor Suppression (103)
A Postdoctoral Scholar position is available in the laboratory of Dr. Pier Paolo Scaglioni in the Department of Internal Medicine, Division of Hematology Oncology, UT Southwestern Medical Center at Dallas, USA. Ph.D. and/or M.D. with a strong background in the field of cellular/cancer biology is required. Areas of interest include the characterization of the tumor suppressive functions of the promyelocytic leukemia gene in hematopoietic malignancies and in solid tumors, and the study of the role of oncogenic K-RAS in initiating and maintaining non-small cell lung cancer. These research topics will be addressed with a combination of molecular/cellular biology techniques and mouse genetics taking advantage of lung cancer and leukemia mouse models. For preliminary data please refer to our recent publications: Cell. 2006. 126:269-83; Nature. 2006. 441:523-7; and Nat Cell Biol. 2004. 6:665-72 and to our lab website: http://www4.utsouthwestern.edu/scaglionilab/default.asp.
Candidates should send their CV, career statement, and contact information for three references to:
Pier Paolo Scaglioni, M.D.
email: HemOncResearch@utsouthwestern.edu
UT Southwestern is an Equal Opportunity/Affirmative Action Employer
Cardiology, Department of Internal Medicine
There are no available positions at this time.
UT Southwestern is an equal opportunity/affirmative action employer.
Cell Biology
Mechanisms of Signal Transduction within Cilia and Flagella (110)
Job Description:
A postdoctoral position is available to study the cell and molecular mechanisms of signal transduction within the flagella of the unicellular green alga, Chlamydomonas. Our laboratory has shown that intraflagellar transport is essential for coupling receptor binding on the flagellar membrane to activation of a signal transduction pathway within the flagella. We are taking advantage of our ability to isolate biochemical quantities of flagella from Chlamydomonas, the availability of Chlamydomonas bearing mutations in specific signaling pathways, and the ease of working with this simple biflagellated eukaryote to discover fundamental properties of cilium-generated signaling.
Job Requirements:
Candidates are expected to have a Ph.D. with a strong background in cell and molecular biology.
Key word: postdoc; postdoctoral fellow
Job Details:
Discovery Science, Primary Research
To Apply:
Please submit CV and three letters of recommendation to:
William J. Snell, Ph.D.
Department of Cell Biology,
University of Texas Southwestern Medical School Rm. K2-226
5323 Harry Hines Blvd.
Dallas, TX 75390-9039
Email:cilia@utsouthwestern.edu
The University of Texas Southwestern Medical Center is an Affirmative Action/Equal Opportunity Employer. Women and minority candidates are encouraged to apply.
Cellular And Molecular Mechanisms Of Cilium-Based Signaling And Intraflagellar Transport (105)
A postdoctoral position is available to study the cell and molecular biology of cilium-generated signaling and intraflagellar transport during fertilization in the green alga Chlamydomonas. The anticipated start date is October 1, 2009.
The candidate is expected to have a Ph.D. degree with a strong background in molecular and cell biology and biochemistry. Applicants should submit curriculum vitae with names and contact information of three references to:
Dr. William J. Snell
Department of Cell Biology
UT Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, Texas 75390-9039
Email: william.snell@utsouthwestern.edu
Cell Signaling and Cancer (98)
Two NIH-funded postdoctoral positions are available immediately for highly motivated individuals to study the cellular and molecular mechanisms underlying cytokine receptor signaling in hematopoietic stem and progenitor cells, and in hematological malignancies. For more information see: http://www4.utsouthwestern.edu/huanglab/contact.htm
A recent Ph.D. degree with strong background in molecular biology, biochemistry, and tissue culture is required. Prior experience with mouse models is desirable. Please send (via email if possible) curriculum vitae and names and contact information of three (3) references to:
Lily Huang, Ph.D.,
Assistant Professor
Department of Cell Biology
University of Texas Southwestern Medical Center at Dallas
5323 Harry Hines Boulevard
Dallas, TX 75390-9039
Lily.Huang@utsouthwestern.edu
UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer
Center for Human Nutrition
There are no positions available at this time.
Clinical Sciences
There are no positions available at this time.
Computational and Systems Biology (117)
Full-time postdoctoral positions are available in the Altschuler and Wu laboratories.
The Altschuler and Wu labs are focused on understanding how biological networks give rise to precise spatial-temporal behaviors within individual cells, and how cellular heterogeneity affects the physiology and pathology of cellular populations. Recent work has investigated these questions in several biological processes, including cell polarization, cellular differentiation, and cancer:
- On heterogeneity in the physiological states and pharmacological responses of differentiating 3T3-L1 preadipocytes, Journal of Cell Biology 2009.
- On an approach for extensibly profiling the molecular states of cellular subpopulations, Nature Methods 2009.
- Characterizing heterogeneous cellular responses to perturbations, PNAS 2008.
- On the spontaneous emergence of cell polarity, Nature 2008.
- Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity, Cell 2007.
- Multi-dimensional drug profiling by automated microscopy, Science 2004.
Our labs are highly multi-disciplinary and collaborative. Researchers with diverse backgrounds will have the opportunity to work side-by-side within our lab and benefit from the collaborative research community at UT Southwestern.
Lab web site: http://www4.utsouthwestern.edu/altschulerwulab/default.htm
Applicants should have a strong interest in quantitative biology, with a Ph.D. in the biological, engineering, mathematical, or physical sciences. Applicants should submit a brief one-page description of research interests, a resume, and contact information for three references to Dr. Altschuler or Dr. Wu via e-mail (Steven.Altschuler@UTSouthwestern.edu or Lani.Wu@UTSouthwestern.edu).
UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employe
Department of Dermatology
There are no positions available at this time.
Developmental Biology Department
There are no positions available at this time.
UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer
Digestive and Liver Diseases, Internal Medicine
NF-kB regulation, ubiquitination and inflammatory responses in mouse models (93)
The Department of Internal Medicine, Division of Digestive and Liver Diseases, has a post-doctoral position available to study NF-kB regulation, ubiquitination and inflammatory responses in mouse models. Laboratory is focused on the ubiquitination of NF-kB/RelA and its role in inflammatory responses (EMBO Journal, 26: 459-467, 2007; Genes & Development, 23: 849-861, 2009). Additional information about our research area can be found at http://www.utsouthwestern.edu/utsw/cda/dept24482/files/536923.html. Candidates with PhD or equivalent degree and a demonstrated track record in molecular biology, and mouse models of inflammation are preferred.
Send complete curriculum vitae and three references to:
Dr. Ezra Burstein
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, Texas 75230-9151
ezra.burstein@utsouthwestern.edu
UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer
Endocrinology
There are no positions available at this time.
Hematology Oncology, Internal Medicine
Molecular Mechanisms of Resistance to Hormonal Therapy of Prostate Cancer (122)
A postdoctoral position is available in the laboratory of Dr. Nima Sharifi in the Division of Hematology/Oncology.
This laboratory is focused on molecular mechanisms of androgen receptor (AR) gain-of-function that lead to resistance to androgen deprivation therapy and the translational relevance thereof. Areas of interest in this laboratory include:
- Specific mechanisms that lead to “ligand-independent” AR gain-of-function.
- Metabolic and genetic changes required for androgen synthesis from adrenal precursors.
- Animal models of advanced prostate cancer that are useful for translational and therapeutic studies.
The candidate should hold a doctoral degree with a background in transcriptional regulation, metabolism or cancer biology. Candidates with an interest in the position should send their CV and contact information for 3 references to:
Nima Sharifi, M.D.
Assistant Professor
Division of Hematology/Oncology
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8852
c/o Hem/Onc Research
HemOncResearch@utsouthwestern.edu
Molecular Mechanisms of Tumor Suppression (103)
A Postdoctoral Scholar position is available in the laboratory of Dr. Pier Paolo Scaglioni in the Department of Internal Medicine, Division of Hematology Oncology, UT Southwestern Medical Center at Dallas, USA. Ph.D. and/or M.D. with a strong background in the field of cellular/cancer biology is required. Areas of interest include the characterization of the tumor suppressive functions of the promyelocytic leukemia gene in hematopoietic malignancies and in solid tumors, and the study of the role of oncogenic K-RAS in initiating and maintaining non-small cell lung cancer. These research topics will be addressed with a combination of molecular/cellular biology techniques and mouse genetics taking advantage of lung cancer and leukemia mouse models. For preliminary data please refer to our recent publications: Cell. 2006. 126:269-83; Nature. 2006. 441:523-7; and Nat Cell Biol. 2004. 6:665-72 and to our lab website: http://www4.utsouthwestern.edu/scaglionilab/default.asp.
Candidates should send their CV, career statement, and contact information for three references to:
Pier Paolo Scaglioni, M.D.
email: HemOncResearch@utsouthwestern.edu
UT Southwestern is an equal opportunity/affirmative action employer.
Hypertension, Department of Internal Medicine
There are no positions available at this time.
Department of Immunology
Image and Signal Processing for Fluorescence Microscopy (116)
A post-doctoral position is available to work on fluorescence microscopy related projects in a joint research group with Prof. Raimund J. Ober.
The NIH supported projects aim to develop novel imaging modalities, image processing and data analysis methods for fluorescence microscopy of live cells and, in particular, single molecule experiments.
The positions will provide the opportunity to not only work on projects of significant technical interest but also to become familiar with the fundamental biological questions that are being addressed in the laboratory. Specifically, the laboratory investigates the trafficking of antibodies in live cell environments. A main emphasis of the research is the investigation of the effects of the engineering of antibody interactions with Fc receptors on the cellular trafficking behavior and in vivo properties.
For further details please see www4.utsouthwestern.edu/wardlab, or publications such as Optics Express, 17, 6881-6898; Biophys J., 95, 6025-6043, 2008; Proc. Natl. Acad. Sci. USA, 104, 5889-5894, 2007; Proc. Natl. Acad. Sci. USA, 103, 4457-4462, 2006; Nature Biotechnol., 23, 1283-1288, 2005; Proc. Natl. Acad. Sci. USA, 101, 11076-11081, 2004; IEEE Transactions Nanobioscience, 3, 237-242, 2004; J. Immunol., 172, 2021-2029, 2004; Biophys. J., 86, 1185-1200, 2004.
Please send enquiries (resume, names of at least three referees etc.) to:
Prof. E. Sally Ward
University of Texas Southwestern Medical Center at Dallas
email: wardlab@utsouthwestern.edu
UT Southwestern is an Equal Opportunity, Affirmative Action Employer.
Division of Infectious Diseases, Department of Internal Medicine
Autophagy Roles in Cell Death Regulation, Cancer Biology, and Infectious Diseases (104)
Postdoctoral Research Positions available to study the molecular mechanisms, regulation, and functions of autophagy, including its roles in cell death regulation, cancer biology, and infectious diseases. Ph.D. and/or M.D. required. Candidates should have a strong foundation in molecular biology, cell biology, and/or biochemistry.
Send curriculum vitae and three letters of reference to:
Beth Levine, M.D.
Howard Hughes Medical Institute
Department of Internal Medicine
University of Texas Southwestern Medical Center
Dallas, Texas, 75390-9113
E-mail: cindy.jozefiak@utsouthwestern.edu
Laboratory website: http://www4.utsouthwestern.edu/idlabs/Levine/Levine_intro.htm
|
| Home > Education > Graduate School >
