Advanced Imaging Research Center
Brain Plasticity Post-Doctoral Fellowship
A well-funded post-doctoral research position is available at University of Texas at Dallas’ Center for BrainHealth and the Advanced Imaging Research Center at The University of Texas Southwestern Medical Center at Dallas. This position presents the opportunity to design and conduct neuroimaging and cognitive studies focused on normal aging, and aging populations with degenerative diseases including Alzheimer’s disease, Mild Cognitive Impairment, and Frontotemporal dementias. Candidates must have an advanced degree (PhD or MD) in cognitive neuroscience, medicine, or medical imaging. UTD and UTSW have embarked on a multi-million dollar expansion of human neuroscience research that includes a new 6-story $60M Advanced Imaging Research Center (AIRC) and the unique, multi-disciplinary Center for Brain Health. The Center is housed in a newly constructed state-of-the art building and is the site of more than 30 ongoing projects based on active multi-disciplinary collaborations among Neurologists, Cognitive Scientists, Rehabilitation experts and Biophysicists. The AIRC houses several high-field, research-dedicated MR systems including research-dedicated Philips 3T and 7T Human systems. The AIRC is performing state-of-the-art studies in brain morphometry, function, perfusion, DTI, and MRS. These joint cognitive neuroimaging projects will be under the supervision of Drs. John Hart, Sandra Chapman, and Hanzhang Lu.
Please send cover letter and CV to:
Dr. John Hart
Center for BrainHealth
University of Texas at Dallas
2200 W. Mockingbird Lane
Dallas, TX, 75235
E-mail: sharon.omeara@utdallas.edu.
UT Southwestern is an Equal Opportunity/Affirmative Action Employer
Department of Biochemistry
HPLC/Mass Spectrometry
A postdoctoral associate position is available immediately to join an interdisciplinary research group studying dynamics of protein modifications (e.g., phosphorylation and lysine acetylation) in cellular regulations and diseases, using nano-HPLC/mass spectrometry-based technologies. The successful candidates should require a Ph.D. degree, intensive training in the fields of separation science (e.g., HPLC) and protein chemistry.
If you are interested, please email your CV and the names of three references to:
Yingming Zhao, Ph.D.
Department of Biochemistry, RM L4.244
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9038
Phone: 214-648-8856
email: Yingming.Zhao@UTSouthwestern.edu.
Harold C. Simmons Comprehensive Cancer Center 
Postdoctoral Fellow in Transcriptional Regulation
Research Area: Transcription, Chromatin, Gene Regulation and Molecular Virology
Description of project: Several postdoctoral positions are available to study mechanisms of chromatin-dependent transcription and posttranslational modification of transcription factors, cofactors and the general transcription machinery. In vitro-reconstituted chromatin transcription systems are frequently used in the lab to identify the factors and pathways leading to gene activation and repression. Current studies include functional interplays between tumor suppressor proteins, such as p53, and various DNA tumor virus-encoded oncoproteins. Several cellular chromatin adaptors, including Brd4 and SMC5/SMC6, are also studied to define their roles in mediating cellular and viral gene expression.
Applicants with a Ph.D. degree and a strong background in protein biochemistry, molecular biology and virology are encouraged to apply.
Please forward your CV and three letters of recommendation to:
Dr. Cheng-Ming Chiang
Simmons Comprehensive Cancer Center
UT Southwestern Medical Center
5323 Harry Hines Blvd., ND2.210H
Dallas, Texas 75390-8807
Phone: (214) 645-6128
Fax: (214) 645-6347
E-mail: Cheng-Ming.Chiang@UTSouthwestern.edu
UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer
Cardiology, Department of Internal Medicine
There are no positions available at this time.
Cell Biology
There are no positions available at this time.
Clinical Sciences
Computational systems biology
The Department of Clinical Sciences at UT Southwestern Medical Center (Dallas, TX) is offering a postdoctoral position in computational systems biology.
The successful candidate will have the opportunity to work on an exciting project analyzing host-pathogen interactions in collaboration with experimental labs. The project involves the development of algorithms for reconstructing biological networks, analyzing such networks by integration with genome-scale data and potentially develop predictive computer models.
The ideal candidate would have an interdisciplinary background with a Ph.D. in Biochemistry, Computer Science, Mathematics, Molecular Biology, Physics or Statistics. Substantial training in computer science/theoretical biology with knowledge in molecular biology, as well as programming experience in C , Java, Perl, Python is required. A basic understanding in graph theory and immunology is preferred.
Interested applicants should send a CV/resume and three reference letters to Dr. Christian Forst @ (pam.oliver@utsouthwestern.edu).
UT Southwestern is an Equal Opportunity, Affirmative Action Employer.
Department of Dermatology
There are no positions available at this time.
Developmental Biology Department
Molecular mechanisms and translational research in kidney cancer
A postdoctoral position is available in the Brugarolas lab for entrepreneurial individuals pursuing a career in Academia who are interested in Cancer Biology.
The Brugarolas lab focuses on understanding kidney cancer. Specifically we are interested in:
- Dissecting pathways involved in kidney cancer development, such as the mTOR pathway.
- The discovery, using genomic platforms, of new pathways implicated in the pathogenesis of kidney cancer.
- The development of novel paradigms for the evaluation of molecularly targeted therapies for kidney cancer.
To attain these goals, multiple approaches are utilized in the lab. Ongoing projects include: an RNAi screen of the Drosophila kinome, affinity chromatography studies to identify interacting proteins, genomic analyses of patient tumor samples, a synthetic lethal screen to identify tumor specific targets, molecular studies of drugs approved for use in patients with kidney cancer, as well as a variety of cellular and molecular biology projects. In addition, the laboratory works with several genetically engineered mouse models harboring mutations in various tumor suppressor genes including Vhl, Tsc1, Tsc2 as well as REDD1.
The laboratory offers an extraordinarily rich environment that encompasses both basic and translational research for highly motivated individuals interested in Cancer Biology.
For more information see: http://www4.utsouthwestern.edu/brugarolaslab/
Position requirements: candidates should hold an MD/PhD or PhD degree and be interested in a career in Academia.
Interested individuals should send the following information:
- A statement of interest explaining the reasons why the candidate is interested in the position and how the position might further the candidate’s career goals.
- An updated CV.
- Names and contact information for 3 professional references.
James Brugarolas, M.D., Ph.D.
Assistant Professor
c/o Bradley Hicks
Sr. Administrative Assistant
5323 Harry Hines Blvd.
Dallas, Tx 75390-9133
Bradley.Hicks@utsouthwestern.edu
UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer
Endocrinology
There are no positions available at this time.
Hematology Oncology, Internal Medicine
Molecular mechanisms of prostate cancer and androgen receptor function
A postdoctoral position is available in the laboratory of Dr. Nima Sharifi.
The central focus of this laboratory program is on molecular mechanisms of gain-of-function of the androgen receptor in advanced prostate cancer. Specific goals of this program are:
- Elucidation of mechanisms of androgen receptor gain-of-function in prostate cancer that is resistant to hormonal therapy
- Interrogation of androgen receptor transcriptional control
- Devising novel methods of inhibiting androgen receptor transcription with synthetic chemist collaborators
The philosophy of the Sharifi laboratory program is that a multidisciplinary approach using molecular biology, pharmacology and chemistry is required to make gains in clinical oncology. Accordingly, the laboratory is in search of a postdoctoral fellow who can be focused on the issues in question, yet is able to communicate effectively with colleagues and collaborators. Candidates must have an M.D. and/or a Ph.D. degree. Interested individuals should submit a CV, statement of interest and the names and contacts of three references to:
Nima Sharifi, M.D.
Division of Hematology/Oncology
5323 Harry Hines Blvd.
Dallas, TX 75390-9133
Nima.Sharifi@utsouthwestern.edu
Molecular Mechanisms of Tumor Suppression
The Department of Internal Medicine, Division of Hematology Oncology, has a postdoctoral position available in the laboratory of Dr. Pier Paolo Scaglioni. Areas of interest include:
1. Characterization of the tumor suppressive functions of the Promyelocytic leukemia gene,
2. Study of the properties of oncogenic K-RAS mutants,
3. Elucidation of the mechanisms responsible for tumor maintenance.
These research topics will be addressed with a combination of molecular/cellular biology techniques and mouse genetics taking advantage of lung cancer and leukemia mouse models. For preliminary data please refer to our recent publications: Cell. 2006. 126:269-83; Nature. 2006. 441:523-7; and Nat Cell Biol. 2004. 6:665-72.
Candidates must have an M.D. and/or a Ph.D. degree. Experience in the field of cellular/cancer biology is recommended. Interested individuals should submit CV, a statement of interest explaining why the candidate is interested in the position and how the position might further the candidate’s career goals, and three (3) references to:
Pier Paolo Scaglioni, M.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8852
HemOncResearch@utsouthwestern.edu
UT Southwestern is an equal opportunity/affirmative action employer.
Hypertension, Department of Internal Medicine
There are no positions available at this time.
Department of Immunology
There are no positions available at this time.
Division of Infectious Diseases, Department of Internal Medicine
There are no positions available at this time.
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