Original Articles

1. Zigman JM, Westermark GT, LaMendola J, Boel E, Steiner DF.   Human G olf alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.  Endocrinology 1993;133:2508-2514.
2. Zigman JM, Westermark GT, LaMendola J, Steiner DF.   Expression of cone transducin, Gz alpha and other G-protein alpha-subunit messenger ribonucleic acids in pancreatic islets.  Endocrinology 1994;135:31-37.
3. Zigman JM, Cohen SE, Garber JR.   Impact of Thyroxine Binding Globulin on Thyroid Hormone Economy During Pregnancy.  Thyroid.  2003;13:1169-1175.
4. Zigman, JM, Garber JR.   Increased TBG during pregnancy and increased hormonal requirements:   Authors' Response.  Thyroid.  2004;14:480-481.
5. Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK.   Mice lacking ghrelin receptors resist the development of diet-induced obesity.   J Clin Invest.  2005;115:3564-3572.
6. Zigman JM, Jones JE, Lee CE, Saper CB, Elmquist JK.   Expression of Ghrelin Receptor mRNA in the Rat and the Mouse Brain.   J Comp Neurol.  2006;494:528-548.
7. Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua Jr. S, Elmquist JK, Lowell BB.    Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.  Neuron.  2006;49:191-203.
8. Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang C-Y, Yu J, Boss O, Mountjoy KG, Clifton PG, Lowell BB, Friedman JM, Horvath T, Butler AA, Elmquist JK, Cowley MA.   Serotonin reciprocally regulates melanocortin neurons to modulate food intake.  Neuron.  2006;51:239-249.
9. Clegg, DJ, Brown LM, Zigman JM, Kemp CJ, Strader AD, Benoit SC, Woods SC, Mangiaracina M, Geary N.   Estradiol-dependent decrease in the orexigenic potency of ghrelin in food intake.  Diabetes.  2007;56:1051-1058.
10. Tong Q, Ye C, McCrimmon RJ, Dhillon H, Choi B, Kramer MD, Yu J, Yang Z, Christiansen LM, Lee CE, Choi CS, Zigman JM, Shulman GI, Sherwin RS, Elmquist JK, Lowell BB.  Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia.  Cell Metabolism 2007;5:383-393.
11. Lutter M, Sakata I, Osborne-Lawrence S, Rovinsky SA, Anderson JG, Jung S, Birnbaum S, Yanagisawa M, Elmquist JK, Nestler EJ, Zigman JM.  The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress.  Nat Neurosci.  2008; 11:752-753.
12. Xu Y, Jones JE, Lee CE, Choi MJ, Anderson JG, Heisler L, Zigman JM, Lowell BB, Elmquist JK.  5-HT_2CRs Expressed by Pro-opiomelanocortin Neurons Regulate Energy Homeostasis.  Neuron. 2008; 60:582-589.
13. Fukuda M, Jones JE, Olson D, Hill J, Lee CE, Gautron L, Choi M, Zigman JM, Lowell BB, and Elmquist JK.  Monitoring FoxO1 localization in chemically identified neurons.  J Neurosci.  2008; 28:13640-13648.
14. Davies JS, Kotokorpi P, Eccles SR, Barnes SK, Tokarczuk PF, Allen SK, Whitworth HS, Guschina IA, Evans BA, Mode A, Zigman JM, Wells T. Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention.  Mol Endocrinol.  2009; 23:914-924.
15. Sakata I, Nakano Y, Osborne-Lawrence S, Rovinsky SA, Lee CE, Perello M, Anderson JG, Coppari R, Xiao G, Lowell BB, Elmquist JK, Zigman JM. Characterization of a novel ghrelin cell reporter mouse. Reg Peptides.  2009; 55:91-98.
16. Sakata I*, Yang J*, Lee CE, Osborne-Lawrence S, Rovinsky SA, Elmquist JK, Zigman JM. Co-localization of ghrelin O-acyltransferase (GOAT) and ghrelin in gastric mucosal cells.  AJP Endo Metab.  2009; in press.

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Reviews, Chapters, and Editorials

1. Zigman J.   Obesity.   In:  Lucas BP, Halasyamani LK, editors.  Pocket Primary Care.  Philadelphia:  Lippincott, Williams, & Wilkins; 2001.  p. 15.
2. Zigman J.   Muscle cramps.   In:  Lucas BP, Halasyamani LK, editors.  Pocket Primary Care.  Philadelphia:   Lippincott, Williams, & Wilkins; 2001.  p. 191-192.
3. Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Zigman JM, Cone RD, Elmquist JK.   Central serotonin and melanocortin pathways regulating energy homeostasis.  Ann NY Acad Sci 2003;994:169-174.
4. Zigman JM, Elmquist JK.   Minireview: From anorexia to obesity -- the yin and yang of body weight control.  Endocrinology 2003;144:3749-3756.
5. Elmquist J, Zigman J, Lutter M.   Molecular determinants of energy homeostasis.   Am J Psychiatry 2006;163:1137.
6. Zigman JM, Elmquist JK.  The search for an effective obesity treatment: A shot in the dark or a shot in the arm?  PNAS 2006; 103:12961-12962. 
7. Nogueiras R, Tschöp MH, Zigman JM.  CNS regulation of energy metabolism:  ghrelin versus leptin.  Ann NY Acad Sci. 2008;1126:14-19.
8. Lee S, Zigman JM.  New molecular targets for the treatment of obesity.  www.endotext.org website, version of 4/24/08, ed. M. Tschoep, published by Mdtext.com, Inc., S. Dartmouth, MA.