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Tissue Management

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Description: Initiated in 2003, this shared resource provides specimen procurement and ancillary services to UT Southwestern Medical Center investigators. The Tissue Management resource includes 5 labs with an extensive collection of equipment to facilitate tissue based research.  DNA and RNA fractions are routinely isolated from fresh samples for use in the molecular analysis of cancer pathogenesis. Laser capture microdissection of tissue sections is offered for investigators wishing to isolate specific cells within a tissue sample for further analysis.

This resource also offers services for the construction of tissue micro-array in which as many as 825 samples can be arrayed on a single microscope slide for immuno-histochemical analysis of protein expression across a large sampling of tumor and normal tissue.  Samples available to researchers include over 6,000 specimens. Departments involved to date include Breast Oncology, Gastroentorology, Hematology Oncology, Surgical Oncology, Urology, OB/Gyn Oncology, and Transplant and Autopsy Services.

Investigators can access these resources online through the Biomaterial Tracking and Management software application at http://tbank.swmed.edu:8050/btm-inves in order to view the samples currently available in the tissue bank, to order samples, to track the status of their orders and to obtain the clinical, pathological and demographic data associated with their samples.

 



Director:

Co-Director:

Manager &Contact:

Associated Staff: 

Richard H. Scheuermann, Ph.D.

Payal Kapur, M.D.

Jennifer Sayne, 214-648-5938, jennifer.sayne@utsouthwestern.edu

Chandana Padukudru, Johann Correos, Celisa Cox

 


 

 

Location:

Center for Human Growth & Development
Simmons Biomedical Research Building / North Campus

 

     

Fee Schedule: 

Sample Procurement

$10 per sample

Laser Capture Microdissection

$100 per tissue block

Tissue Microarray

$45 set up fee, $5 per block ($0.50 each additional punch per block)

Cell/Tissue Culture

$50  per specimen

RNA, DNA and Protein Extraction

$9 per sample

OCT Embedding

$6 per specimen

Paraffin Embedding

$6 per specimen

Block Sectioning 

$8 per block

H&E Staining of Slides

$25 up to 30 slides

Follow-up Information

$15.50 per patient

Slide Evaluation

$5 per slide 

Experion Analysis

$75 per chip (up to 12 samples)

 

Simmons Shared Resources

 

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