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2006 Summer Research Program for Students
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The STARS Summer Research Program gives science teachers and students an opportunity to work in a research environment.  During the summer of 2006, 8 secondary science teachers from around the state of Texas, 16 high school juniors from the Dallas ISD, and 4 Eastfield College students started an eight-week summer internship working in research laboratories on the UT Southwestern Campus and affiliated institutions. Under the guidance of a faculty host, participants complete a research project and present their findings at the end of the summer.

 

    STARS Students

Cindy Camacho
Townview Health Professions High School

Host:
Ray MacDonald, Ph.D.
Molecular Biology

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Using embryonic pancreatic cells to search for new transcription factors that are responsible for the regulation of endocrine cells, which may eventually lead to insulin producing cells as treatment for diabetic patients.

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 Gypsy Gavia
Townview Talented & Gifted High School

Host:
YuhMin Chook, Ph.D.
Pharmacology

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Studying protein substrates (through cloning DNA) that will be carried into the nucleus by a nuclear transport protein.

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Richard Gomez
Thomas Jefferson High School

Host:
Vanessa Sperandio, Ph.D.
Microbiology

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Cloning the lacI gene, which is involved in the transport and metabolism of lactose in E. coli, in addition to studying the regulatory cascade involved in quorum sensing regulation of virulence genes in EHEC (enterohemorrhagic Escherichia coli).

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Tanya Hendricks
James Madison High School

Host:
Nancy Monson, Ph.D.
Neurology & Center for Immunology

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Investigating the role that B cells may play in the pathogenesis of Multiple Sclerosis by comparing the B cell antibody repertoire of MS patients vs. healthy controls.

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Jay Hennig
Booker T Washington High School
for Visual & Performing Arts

Host:
Alexander Pertsemlidis, Ph.D.
McDermott Center for
Human Growth Development

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Making the association calculations between SNPs and phenotype more efficient by utilizing a grid infrastructure that will utilize idle computers around campus.

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Eneida Male
Townview Science & Engineering High School

Host:
Paula Ulery, Ph.D.
Psychiatry

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Determining whether or not the Stx-1 function is regulated by phosphorylation, and how it impacts neurotransmitter release which may play a role in schizophrenia.

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Elianne Ortiz
Townview Science & Engineering High School

Host:
Jenny Hsieh, Ph.D.
Molecular Biology & Green Center

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Studying NRSF regulation of neuronal genes in dentate gyrus after kainic acid induced seizures in a rat model.

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Andrew Palacios
Townview Health Professions High School

Host:
Michel Saint-Cyr, M.D.
Plastic Surgery

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Evaluating the performance and viability of a new suture for tendon repair and dermal closure as compared to current standard sutures.

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Jorge Pereda
Roosevelt High School

Host:
Kristine Kamm, Ph.D.
Physiology

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Identifying the changes in expression of Myosin Phosphatase in a skeletal muscle differentiation model.

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Nevena Rakonjac
Hillcrest High School

Host:
Zbysek Otwinowski, Ph.D.
Biochemistry

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Expressing, purifying, and optimizing crystallizing conditions for three Structural Genomics proteins in order to eventually determine their structure using crystallography technique of X-ray diffraction.

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Chris Renard
Townview Talented & Gifted High School

Host:
Skip Garner, Ph.D.
McDermott Center,
Biochemistry, Internal Medicine

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Refining and extending a textual comparison engine (http://invention.swmed.edu/etblast/index.shtml)  to load and search multiple databases, including MEDLINE, Nasa, and IOP (international journal of physics) records.

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Flor Rojas
Roosevelt High School

Host:
Vidu Garg, M.D.
Pediatrics

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Identifying novel genetic etiologies of congenital heart disease by studying a large family with autosomal dominant atrial septal defects.

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Neri Sandoval
Molina High School

Host:
Dominika Borek, Ph.D.
Biochemistry

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Growing Crystals in a variety of conditions to compare the impact of those conditions on radiation damage.

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Pooja Sarkar
Townview Science & Engineering High School

Host:
Jef De Brabander, Ph.D.
Biochemistry

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Working on the optimization of peptide-coupling reactions that produce oxazole precursors. An oxazole is a cyclic compound that contains an oxygen atom and a nitrogen atom separated by one carbon atom. These are naturally occuring anti-tumor compounds.

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Thuy Tran
WT White High School

Host:
Michael Roth, Ph.D.
Biochemistry

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Patrick Ward
Townview Talented & Gifted High School

Host:
Diana Tomchick, Ph.D.
Biochemistry

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Researching the structure of a variety of bacterial lipoproteins through X-ray crystallography in order to determine the mechanisms of pathenogenicity.

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     STARS ASSOCIATES

Honoria Bush
Parish Episcopal High School

Hosted By:
Peter Antich, Ph.D.
Radiology

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Testing different drugs that may increase  the ability to image proteins associated with Alzheimer's Disease within brain tissue.

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 Catherine Gibson
Greenhill School

Hosted By:
Robert Toto, M.D.
Internal Medicine - Nephrology

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Researching the relationship between the severity of kidney disease and dyslipidemia in diabetic patients.

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Charles Koshy
TAMS

Hosted By:
Mala Mahendroo, Ph.D.
Obstetrics & Gynecology

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Looking for patterns of expression for the gene RIP140 in the cervix compared to other genes using mouse tissue to find out what makes the cervix change from rigid to flexible.

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Jonathan Lee
Jesuit College Preparatory
School of Dallas

Hosted By:
Jim Thornton, M.D.
Plastic Surgery

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Researching the etiology, prevention, and correction of a surgical defect known as temporal hollowing.

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Xavier McCullough
WT White High School

Hosted By:
David Mangelsdorf, Ph.D.
Pharmacology

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 Identifying liver-specific LXRalpha knockout mice by genotyping PCR and investigate the effects of the loss of LXRalpha in the liver on plasma lipid profile and liver gene expression.

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Alyssa Pazandak
The Hockaday School

Hosted By:
Kim Orth, Ph.D.
Molecular Biology

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Researching the host pathogen interactions and regulatory mechanisms involved in signalling in the YopJ family of proteins.  Specifically, working on increasing the yield of purified recombinant XopJ protein to begin crystallization trials to solve the protein structure.

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Emily Rowan
The Hockaday School

Hosted By:
Hiromi Yanagisawa, M.D., Ph.D.
Molecular Biology

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A family of genes known as fibulin plays an important role in elastogenesis, namely in the arteries and lungs. We are working to create a stable transfected cell line that contains the fibulin-3 protein. With this cell line, we will then be able to perform a co-immunoprecipitation study to see how the various proteins interact with each other.

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Aatman Shah
Plano Senior High School

Hosted By:
Jerry Shay, Ph.D.
Cell Biology

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Working to see if there is a synergistic effect between a telomerase enzyme inhibitor, chemotherapy, and an oncolytic adenovirus in inhibiting pancreatic cancer cells.

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Lindsey Smith
Bishop Lynch High School

Hosted By:
Dean Smith, M.D., Ph.D.
Pharmacology

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Mutating OSE & OSF in Drosophila melanogaster to understand the basic principles of chemosensory transduction and information processing.

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April Tipton
Kaufman Highs School

Hosted By:
Eric Nestler, M.D., Ph.D.
Psychiatry

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Researching how alterations in the levels of a growth factor may contribute to depression-related behavior and responses to antidepressants.

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