DCS 5109:
Genetic & Molecular Science
for the Clinical Investigator

Concepts and techniques in molecular biology and genetics; identification of genes and mutations; linkage analysis; molecular and cellular biomarkers; single nucleotide and restriction fragment length polymorphisms; microarray analysis, proteomics; pharmacogenomics; acquisition and storage of samples.  Course objectives are:

1. an understanding of genetic and molecular biological concepts and terminology
2. to be informed about recent advances in human genetics and genomics
3. to be informed about current methodologies for studying human genetics.
4. to design experiments to investigate genetics of human disease.
5. to conduct experiments to investigate genetics of human disease.

Prerequisites: None

Credit: 1 hour; required for Master's certificate and Clinical Scholar programs

Grading Criteria:  Pass/Fail; Term paper proposal (5 pages, single-spaced) involving genetic study of a disease is required.  Attendance requirement is 75%.

Course Director: Andrew Zinn, MD, PhD, Associate Professor, Eugene McDermott Center for Human Growth And Development (NB10.110A), phone: 214 648-1615; fax: 214 648-1666

Course Administrator: Mack Dressler, Dept. of Clinical Sciences (E5.506)
phone: 214 648-6489, fax: 214 648-3934