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EDUCATION/TRAINING
| Institution and Location | Degree | Years | Field | | The University of North Carolina, Chapel Hill | Ph.D. | 1993 | Biochemistry | | S.U.N.Y. at Stony Brook | B.S. | 1984 | Biochemistry |
RESEARCH AND PROFESSIONAL EXPERIENCE
| 2001 - present | | Assistant Professor, Cecil H. and Ida Green Center for Reproductive Biology Sciences and the Department of Pharmacology. The University of Texas Southwestern Medical Center, Dallas TX. | | 1994 - 2001 | | Postdoctoral Research Fellow, Laboratory of Thomas C. Kaufman, Howard Hughes Medical Institute, Department of Biology, Indiana University, Bloomington, Indiana. |
PUBLICATIONS
Kao LR, Megraw TL. RNAi in cultured Drosophila cells. Methods Mol Biol. 2004;247:443-57.
Megraw TL, Kilaru S, Turner FR, Kaufman TC. The centrosome is a dynamic structure that ejects PCM flares. J Cell Sci. 2002 Dec 1;115(Pt 23):4707-18.
Megraw TL, Kao LR, Kaufman TC. Zygotic development without functional mitotic centrosomes. Curr Biol. 2001 Jan 23;11(2):116-20.
Megraw TL, Kaufman TC. The centrosome in Drosophila oocyte development. Curr Top Dev Biol. 2000;49:385-407. Review.
Megraw TL, Li K, Kao LR, Kaufman TC. The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila. Development. 1999 Jul;126(13):2829-39.
Cho JH, Ha SJ, Kao LR, Megraw TL, Chae CB. A novel DNA-binding protein bound to the mitochondrial inner membrane restores the null mutation of mitochondrial histone Abf2p in Saccharomyces cerevisiae. Mol Cell Biol. 1998 Oct;18(10):5712-23.
Megraw T, Kaufman TC, Kovalick GE. Sequence and expression of Drosophila Antigen 5-related 2, a new member of the CAP gene family. Gene. 1998 Nov 19;222(2):297-304.
Li K, Xu EY, Cecil JK, Turner FR, Megraw TL, Kaufman TC. Drosophila centrosomin protein is required for male meiosis and assembly of the flagellar axoneme. J Cell Biol. 1998 Apr 20;141(2):455-67.
Kao LR, Megraw TL, Chae CB. SHM1: a multicopy suppressor of a temperature-sensitive null mutation in the HMG1-like abf2 gene. Yeast. 1996 Sep 30;12(12):1239-50.
Megraw TL, Kao LR, Chae CB. The mitochondrial histone HM: an evolutionary link between bacterial HU and nuclear HMG1 proteins. Biochimie. 1994;76(10-11):909-16.
Kao LR, Megraw TL, Chae CB. Essential role of the HMG domain in the function of yeast mitochondrial histone HM: functional complementation of HM by the nuclear nonhistone protein NHP6A. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5598-602.
Megraw TL, Chae CB. Functional complementarity between the HMG1-like yeast mitochondrial histone HM and the bacterial histone-like protein HU. J Biol Chem. 1993 Jun 15;268(17):12758-63.
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