Associate Professor of Medicine
Division of Cardiology
University of Texas Southwestern Medical Center
5909 Harry Hines Boulevard, Ste. HA9.133
Dallas, TX 75390-9047
Office: 214-645-7500
Fax: 214-645-7501
E-mail: darren.mcguire@utsouthwestern.edu

Ethics/Medical Humanities Areas of Expertise/Interest:
Clinical Trials; Epidemiology
Human Subject Research Protection/IRB
ICH/GCP

CME Lectures:
Writing Informed Consent Documents
Human Subject Research Protection

Public Lectures:
Human Subject Research Protection

Other Recent Ethics/Medical Humanities Activities:
Ad hoc Faculty, UT Southwestern Medical Center Department of Clinical Sciences
Ethics in Clinical Science
Clinical Research: Proposal to Implementation
Public Policy Considerations in Research
How to Write an Informed Consent Document

Key Publications:

McGuire DK, Anstrom KA, Peterson ED. The influence of the BARI NHLBI diabetic clinical alert on practice patterns: Results from the National Cardiovascular Network database. Circulation 2003; 107:1864-1870.

McGuire DK, Newby LK, Bhapkar MV, Moliterno DJ, Hochman JS, Klein W, Weaver WD, Pfisterer M, Dimas A, Corbalan R, Granger CB, Van de Werf F, Topol EJ, Califf RM, for the SYMPHONY and 2nd SYMPHONY Investigators. Influence of Diabetes Mellitus and Glycemic Control Strategies on Clinical Outcomes After Acute Coronary Syndromes: Findings from the SYMPHONY and 2ND SYMPHONY Studies. Am Heart J 2004; 147: 246-52.

Svensson AM, McGuire DK, Abrahamsson P, Dellborg M. Glycometabolic state at admission and during hospitalization: Important Risk Marker of Mortality in Diabetes Patients with Acute Coronary Events: a 10 year experience . European Heart J, 2005; 38: 229-34.

Khera A, de Lemos JA, Peshock RM, Lo H, Stanek HG, Murphy SA, Wians FH, Grundy SM, McGuire DK. Lack of an Independent Association Between C-Reactive Protein and Subclinical Atherosclerosis: The Dallas Heart Study. Circulation 2006;113 38-43.

Das SR, Vaeth PAC, Stanek HG, de Lemos JA, Dobbins RL, McGuire DK. Under-diagnosis, Increased Coronary Calcium and Sub-optimal Cardiovascular Risk Modification Associated with Diabetes Mellitus in Dallas County: Observations from the Dallas Heart Study. Am Heart J 2006; 151: 1087-93.