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Class 10: 2007-2011
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Neal Alto, Ph.D.
Rita C. and William P. Clements, Jr. Scholar in Medical Research
Assistant Professor, Department of Microbiology
Dr. Alto is interested in understanding the biochemical and cellular basis of host/pathogen interactions with a particular emphasis on mechanisms by which bacteria hijack eukaryotic signal transduction systems. More specifically, the lab studies human Rho GTPase signaling to the actin-microtubule cytoskeleton and determines how pathogens co-opt this critical cellular system via bacterial Type III effector proteins.
Research Interests
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Assistant Professor, Department of Molecular Biology
Dr. Buszczak uses several different types of Drosophila stem cells to study how chromatin organization promotes self-renewal in vivo. The Buszczak lab also seeks to characterize how this intrinsic program changes during the process of differentiation.
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Assistant Professor, Department of Microbiology
Dr. Conrad is interested in the mechanisms of post-transcriptional gene regulation of the Kaposi's sarcoma-associated herpesvirus (KSHV) and its human host cells. Uncovering how unique KSHV factors exploit the host cell machinery to promote viral gene expression will yield a greater understanding of this important pathogen and the fundamental processes involved in human gene expression.
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Chandrashekhar Pasare, Ph.D.
Louise W. Kahn Scholar in Biomedical Research
Assistant Professor, Department of Immunology
Dr. Pasare's research interest is to understand the cellular and molecular mechanisms by which the immune system deals with pathogens. Specifically, he is investigating how receptors of the innate immune system, particularly Toll-like receptors, influence activation of the adaptive immune responses.
Research Interests
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Luke Rice, Ph.D.
Thomas O. Hicks Scholar in Medical Research
Assistant Professor, Department of Biochemistry
Dr. Rice's research is focused on microtubules, dynamic cellular polymers made from alpha/beta-tubulin subunits. Microtubules have essential roles in chromosome segregation, vesicular trafficking, and organelle positioning. His laboratory is integrating biophysical studies of alpha/beta-tubulin, kinetic measurements of microtubule behavior, and computational models of microtubule assembly to discover the molecular mechanisms underlying dynamic microtubule behavior and its regulation.
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Adrian Rothenfluh, Ph.D.
Effie Marie Cain Scholar in Medical Research
Assistant Professor, Department of Psychiatry
Dr. Rothenfluh is investigating genes that contribute to the behavioral responses to alcohol. His laboratory is particularly interested in the dynamic control of the actin cytoskeleton, and how it affects drug responses.
Lab Web Site
Research Interests
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Benjamin Tu, Ph.D.
W. W. Caruth Jr. Scholar in Biomedical Research
Assistant Professor, Department of Biochemistry
Dr. Tu is interested in the study of biological cycles and understanding how fundamental biological processes are coupled to changes in cellular metabolic and redox state.
Lab Web Site
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Felix Yarovinsky, M.D.
Nancy Cain and Jeffrey A. Marcus Scholar in Medical Research, in Honor of Dr. Bill S. Vowell
Assistant Professor, Department of Immunology
Dr. Yarovinsky is exploring molecular and cellular mechanisms of innate immunity to parasitic infections of global importance. He seeks to understand how dendritic cells can initiate and regulate host resistance to Toxoplasma gondii and malaria infections.
Research Interests
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Xuewu Zhang, Ph.D.
Virginia Murchison Linthicum Scholar in Medical Research
Assistant Professor, Department of Pharmacology
Dr. Zhang's lab is studying regulation mechanisms for signaling proteins, especially cell surface receptors, through structural and biochemical analyses.
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Instructions for Endowed Scholar Nominations
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