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Department of Pediatrics: Infectious Disease Fellow Education
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The Division of Pediatric Infectious Disease has a long tradition of training fellows in the subspecialty. Since 1965 86 fellows have completed training in infectious diseases, 80% whom are involved in teaching and research in university-affiliated medical centers.

The purposes of the training program are to provide a background in laboratory techniques of classical microbiology, immunology and molecular biology, to provide experience in application of the scientific method to clinical and laboratory research, and to develop competence in diagnosis and management of infectious diseases.   Clinical training is in the form of consultations, rounds and conferences, and outpatient Infectious Diseases and HIV Clinics.

The Division of Pediatric Infectious Disease is comprised of nine (9) active faculty members, each of whom has specific research and clinical interests: 

Each trainee is instructed in all relevant basic laboratory methods, including fundamentals of aerobic and anaerobic bacteriology, antibiotic susceptibility testing, antibiotic assays, serologic techniques, immunoelectrophoresis, the fluorescent antibody method, tissue culture technique and leukocyte function studies.   Additionally, the fellows have ample opportunity to work with collaborators in molecular microbiology to acquire basic techniques such as PCR, microarray analyses, cloning, purification of bacterial outer membrane components (eg. endotoxin), etc.  The trainee carries through one or more research protocols of his/her own design with supervision by the program directors and collaborators.  This is tailored to the interests and capabilities of the individual trainee either in basic laboratory experimentation or in clinical research.

The clinical material available at Children’s Medical Center and on the neonatal service at  Parkland Memorial Hospital is extensive.   There are approximately 120,000 outpatient visits, 9,000 pediatric admissions and 16,000 deliveries per year.  A high proportion of these have infectious disease problems; therefore, trainees have the opportunity to see many common infections and most of the rarer disorders.  Infectious disease clinical rounds are conducted daily and the clinic is scheduled twice weekly.  We average approximately 60 inpatient consultations monthly and 15-20 new outpatient consultations monthly.

The three-year program aims to provide individuals with sufficient background to pursue a career of independent research, teaching and managing patients with wide variety of pediatric infectious diseases.

Prerequisites include one year of internship and two years of pediatric residency.   Applicants must:

  • Be citizens of the United States or Canada OR
  • Hold a permanent resident visa OR
  • Have passed the USLME examination and be eligible for an ECFMG-sponsored visa.   In addition foreign medical graduates will be required to provide original documentation of education and licensure upon acceptance into the program.

Click Here for Fellowship Application. Print and complete the application in its entirety, then forward it and all relevant material to our office by e-mail, fax or regular mail.

 

Applications should be returned to:                     George McCracken, M.D.
                                                                               Professor of Pediatrics
                                                                              5323 Harry Hines Blvd., F3. 202
                                                                              Dallas, TX  75390-9063
                                                                              Phone:         (214) 648-3439      
                                                                              Fax:              (214) 648-2961
                                                                              E-mail: george.mccracken@utsouthwestern.edu

 

Current Fellows (As of July 1, 2008)

Steven M. Grube, M.D. (3rd Year)

Chonnamet Techasaensiri, M.D. (3rd Year)

Michael Chang, M.D. (2nd year)

Carla Garcia, M.D. (2nd year)

Alejandro Jordan-Villegas, M.D. (1st year)

Amanda S. Evans, M.D. (1st year)

 

Since 1996, five (5) fellows have received two-year fellowship awards from the Pediatric Infectious Diseases Society and three (3) have received MedImmune Fellowship Awards for Viral Respiratory Infections.  Two trainees recently received NIH K08 awards within one year of completing fellowship training.  In each of the last four years, 2-3 fellows have received fellowship travel grants to present their research at the annual international Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) sponsored by the American Society of Microbiology.  Our fellows average eight (8) presentations yearly at international infectious disease and pediatric meetings. 

Selected Recent Publications by Fellows (2006-2008):

•         Fonseca-Aten M., Rios A, Mejias A, Chavez-Bueno S., Katz K, Gomez AM, McCracken G H.Jr, Ramilo 0 and Hardy R.D. Treatment of experimental chronic mycoplasmosis. International J Antimicrob Agents 2006; 28: 253-8.

•         M Fonseca-Aten, PJ Okada, KL Bowlware, S Chavez-Bueno, A Mejias, AM Rios, K Katz, K Olsen, S Ng, HS Jafri, GH McCracken, 0 Ramilo, Hardy RD. Effect of Clarithromycin on Cytokines and Chemokines in Children with an Acute Exacerbation of Recurrent Wheezing: A Double-Blind, Randomized, Placebo-Controlled Trial. Annals of Allergy, Asthma & Immunolcgy. 2006 Oct;97 (4):457-63.

•         Verweel G, Saavedra-Lozano J, van Rossum AMC, Ramilo 0, de Groot R. Initiating highly active antiretroviral therapy in human immunodeficiency virus type-1 infected children in Europe a d the USA; comparing clinical practice to guidelines and literature evidence. Pediatr Infec Dis J 2006 Nov;25(11 ):987-94.

•         Saavedra-Lozano J, Ramos JT , Sanz F, Navarro ML, de Jose MI, Martin-Fontelos P, Mellado MJ, Leon Leal JA, Rodriguez C, Luque I, Madison SJ, Irlbeck D, Lanier ER, Ramilo O. Salvclge Therapy with High-Dose Abacavir and other Reverse Transcriptase Inhibitors in Children With HIV-Associated Encephalopathy. Pediatr Infec Dis J December 2006; 25(12): 1142-52.

•         Ramilo 0., Allman W., Chung W., Mejias A, Ardura M., Glaser C., Wittkowski K. M., Piqueras B., Banchereau J., Palucka K. and Chaussabel D. Gene Expression Patterns in Blood Leukocytes Discriminate patients with Acute Infections. Blood. 2007 Mar 1;109(5):2066-77.

•         Mejias A and Ramilo O. RSV: New approaches to reduce the burden of RSV infection. Drug Discovery Today Therapeutic Strategies 2006: 3 (2): 173-81.

•         Bowlware, K. L., et aI., Cefdinir pharmacokinetics and tolerability in children receiving 25 mg/kg once daily. Pediatr Infect Dis J, 2006. 25(3): 208-10.

•         Santos RP, Sanchez PJ, Mejias A, Benjamin Jr. DK, Walsh T J, Patel S, Jafri HS. Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin. Pediatr Infect Dis J. 2007 Apr;26(4):364-6.

•         Ardura MI, Mejias A, Katz KS, Revell P, McCracken Jr. GH, Sanchez PJ. Daptomycin therapy for invasive Gram-positive bacterial infections in children. Pediatr Infect Dis J. 2007 Dec; 26(12): 1128-32.

•         Perez-Yarza EG, Moreno A, Lazaro P, Mejias A, Ramilo O. The association between respiratory syncytial virus infection and the development of childhood asthma: A systematic review of tile literature. Pediatr Infec Dis J 2007; 26:733-739

•         CM Salvatore, M Fonseca-Aten, K Katz, AM Gomez, A Mejias, C Somers, S Chavez Bueno, GH McCracken, Hardy RD. Respiratory Tract Infection with Mycoplasma pneumoniae in IL-12 Knock­Out Mice Results in Improved Bacterial Clearance and Reduced Pulmonary Inflammation. Infection and Immunity 75:236-242, 2007.

•         Messina AF, Katz-Gaynor K, Barton T, Ahmad N, Ghaffar F, Rasko D, McCracken GH Jr. Impact of the pneumococcal conjugate vaccine on serotype distribution and antimicrobial resistanCE! of invasive Streptococcus pneumoniae isolates in Dallas, TX, children from 1999 through 2005. Pediatr Infect Dis J. 2007 Jun;26(6):461-7.

•         IC Michelow, K Katz, GH McCracken, Hardy RD. Systemic Cytokine Profile in Children with Community-Acquired Pneumonia. Pediatric Pulmonology 42:640-645, 2007.


•         Chavez-Bueno S, Mejias A, Merryman RA, Ahmad N, Jafri HS, and Ramilo O. Intravenous Palivizumab and Ribavirin Combination for Treatment of Respiratory Syncytial Virus Disease in High-Risk Pediatric Patients. Pediatric Infectious Disease 2007.

•         Allantaz F., Chaussabel D., Stichweh D., Punaro M., Bennet L., Allman W, Mejias A, Ardura MI, Chung W, Wise C, Palucka K, Ramilo 0, Banchereau J and Pascual V. Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL­1 blockade. J Exp Med. 2007 Sep 3;204(9):2131-44.

•         Bogdanovich, T., N. Aydin, Chavez-Bueno S., McCracken G., et al. Genetic characterization of erythromycin- and methicillin-resistant community-acquired Staphylococcus aureus isolated from children in Texas. Diagn Microbiollnfect Dis, 2007.

•         CM Salvatore, M Fonseca-Aten, K Katz, AM Gomez, Hardy RD. IntranasallL-12 Therapy In ibits Mycoplasma pneumoniae Clearance and Sustains Airway Obstruction in Murine Pneumonia. Infection and Immunity 76:732-738, 2008.

•         Saavedra-Lozano J, Mejias A, Ahmad N, Peromingo E, Ardura MI, Guillen S, Syed A, Cavuoti D, Ramilo O. Changing Trends in Acute Osteomyelitis in Children: Impact of Methicillin-Resistant Staphylococcus aureus Infections. J Pediatr Orthop. 2008 July/August;28(5):569-575.

•         C Tagliabue, CM Salvatore, C Techasaensiri, A Mejias, JP Torres, K. Katz, AM Gomez, S Esposito, N Principi, Hardy RD. The Impact of Steroids Given with Macrolide Therapy in Experimental Mycoplasma pneumoniae Respiratory Infection. Journal of Infectious Diseases. 2008. (In Press)