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CURRENT FELLOWS

 

O’Hair R, Freitas M, Schmidt J, Hatley M, Williams T.  Gas-Phase Methylation for 2-Hydroxypyridine / 2-Pyridone System by the Dimethylchloronium ion.  European Mass Spectrometry, 1995; 1: 457-463.

Hatley M, Benton B, Xu J, Manfredi J, Gilman A, Sunahara R.  Isolation and Characterization of Constitutively Active Mutants of Mammalian Adenylyl Cyclase.  Journal Biological Chemistry, 2000; 275 (49): 38626-32.

Hatley M, Gilman A, Sunahara R.  Expression, Purification, and Assay of Cytosolic (Catalytic) Domains of Membrane-Bound Mammalian Adenylyl Cyclases.  Methods in Enzymology, 2002; 345: 127-40.

Hatley M, Lockless S, Gibson S, Gilman A, Ranganathan R.  Allosteric Determinants of Guanine Nucleotide Binding Proteins.  Proceedings of the National Academy of Science, 2003; 100: 14445-50.

 

FORMER FELLOWS:  Before 2008

Mangano A, Gonzalez E, Dhanda R, Catano G, Bamshad M, Bock (Blair) A, Duggirala R, Williams K, Mummidi S, Clark R, Ahuja S, Dolan M, Bologna R, Sen L, Ahuja S.  Concordance between CC Chemokine Receptor 5 Genetic Determinants that Alter Risks of Transmission and Disease Progression in Children Exposed Perinatally to Human Immunodeficiency Virus.  The Journal of Infectious Disease, June 2001; 183: 1574-85.

Klesse L and Parada L.  p 21Ras and Phosphatidylinositol-3 Kinase are Required for Survival of Wild-type and NF1 Mutant Sensory Neurons.  Journal of Neuroscience, 1998; 18(24):10420-10428.   

Klesse L, Meyers K, Marshall C, and Parada L. Nerve Growth Factor Induces Survival and Differentiation Through Two Distinct Signaling Cascades in PC12 Cells.  Oncogene, 1999; 18:2055-2068. 

Vogel K*, Klesse L*, Velasco-Miguel S*, Meyers K*, Rushing E, and Parada L.  Mouse tumor model for neurofibromatosis type 1.  Science, 1999; 286(5447): 2176-2179.  (Note:  *authors contributed equally to this work). 

Klesse L and Parada L.  Trks: Signal transduction and intracellular pathways.  Microscopy Research and Technique, 1999; 45: 210-216.  

Kelly-Spratt K, Klesse L, and Parada L.  A TrkB/IRR chimera induces PC12 cell differentitation and exhibits prolonged activation of mitogen-activated protein kinase.  Cell Growth and Differentiation, 1999; 10(12): 805-812.  

Gonzalez-Zulueta M, Feldman A, Klesse L, Kalb R, Dillman J, Parada L, Dawson T, Dawson V.  Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning.  Proc. Natl. Aca. Sci., 2000; 97(1): 436-441. 

Liebl D, Klesse L., Tessarollo L, Wohlman T, and Parada L.  Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice. Proc. Natl. Aca. Sci., 2000; 97(5): 2297-2302. 

Watson F, Heerssen H, Bhattacharyya A, Klesse L, Lin M and Segal R.  Neurotrophins use the Erk5 pathway to mediate retrograde survival response.  Nature Neuroscience, 2001; 4(10):981-988. 

Kelly-Spratt K, Klesse L, and Parada L.  A TrkB/IRR chimera promotes survival of sympathetic neurons by signaling through ras and phosphatidlyinositol-3 kinase.  J. of Neuroscience Research, 2002;  69(2):151-159.            

Bron R, Klesse L,, Shah K, Parada L and Winter J.  Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors. Mol Cell Neuroscience, 2003;   22(1):118-132.

Lei L, Laub F, Lush M, Romero M, Zhou J, Luikart B, Klesse L, Ramierz F and Parada L.  The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons.  Genes & Development, 2005;  19(11): 1354-64. 

Litten J, Kramer R, Romaguera R, Barker J & Tamer A.  “Pediatric Puzzler: Can it be IBD?  Severe Abdominal Findings Overwhelm a 12-year-old.”  Contemporary Pediatrics, 2004.

Litten J.  “50 Years ago in the Journal of Pediatrics – Chronic Benign Neutropenia.”  The Journal of Pediatrics.  June 2006.

Litten J, Rodríguez M, Maniaci V.  “Brief Report: Acute Lymphoblastic Leukemia Presenting in Fulminant Hepatic Failure.”  Pediatric Blood and Cancer, 2006; 47:842-845.

Surka W, Kohlhas J, Neunert C, Schneider D, Proud V.  Unique Family with Townes-Brocks Syndrome, SALL1 Mutation and Cardiac Defects.  American Journal of Medical Genetics, 2001; 102 (3): 250-257.

Neunert C.  50 Years Ago in the Journal of Pediatrics: Measles and Idiopathic Thrombocytopenic Purpura.  Journal of Pediatrics, 2006; 148 (3): 365.

Neunert C, Journeycake J.  Congenital Platelet Disorders.  Hematology and Oncology Clinics of North America, 2007; 21 (4): 663-84, vi.

Wickiser J, Saulsbury F.  Henoch-Schonlein Purpura in a Child with Hyperimmunoglobulinemia D and Periodic Fever Syndrome.  Pediatric Dermatology, 2005, 22(2): 138-141.

Wickiser JE, Thompson M, Leavey PJ, Quinn CT, Garcia NM, Aquino VM.  Extracorporeal Membrane Oxygenation (ECMO) Initiation Without Intubation in Two Children with Mediastinal Malignancy. Pediatric Blood and Cancer, 2007; 49 (5): 751-4.

Crary S, Buchanan G, Journeycake J.  Fatal Central Venous Catheter-Related Infection in Haemophilia.  Haemophilia, 2006; 12: 183-186.

Crary S, Buchanan G, Drake C, Journeycake J. Venous Thrombosis and Thromboembolism in Children with Osteomyelitis.  J Pediatr, 2006; 149:  537-541.

Bolden B, Crary S, Buchanan G, Journeycake J.  Determination of Pediatric Norms for Assessment of Upper Venous System Post-Thrombotic Syndrome.  J Thromb Haemost, 2007; 5 (5): 1077-9.

Huh W and Raney R.  Orbital metastasis in patients with rhabdomyosarcoma:  case series and review of the literature.  J Pediatr Hematol Oncol, 2006; 28:684-7.

Huh W, Gill J, Sheth S and Buchanan GR.   Pneumocystis carinii pneumonia in patients with Diamond-Blackfan anemia receiving high-dose corticosteroids.  J Pediatr Hematol Oncol,  2002; 24: 410-412.

Puleo D, Huh W, Duggirala S and DeLuca P.  In vitro cellular responses to bioerodible particles loaded with recombinant human bone morphogenetic protein-2.  J Biomed Mater Research, 1998; 41: 104-110.

Puleo D and Huh W.  Acute toxicity of metal ions in cultures of osteogenic cells derived from bone marrow stromal cells.  J Applied Biomaterials, 1995; 6: 109-116.

 Collier A.  50 Years ago in the Journal of Pediatrics: Radiotherapy in tumors of childhood. J Pediatr, 2004; 144:484.

Li X, Valdez P, Olvera R, Carrington J.   Functions of the Tobacco Etch Virus RNA polymerase (n1b):  Subcellular Transport and Protein-Protein Interaction with Vpg/Proteinase (n1a) Journal of Virology, 1997: 1598-1607. 

Assanasen C. The St. George’s Health Fair.  The New Physician, 1993; 11: 29.

Assanasen C.  Normal Growth and Development: Milestones in the First Few Years of Life.  Jacksonville Medicine, 2000; 51:10.

Assanasen C, Quinton R, Buchanan G.  Myocardial infarction in sickle cell anemia.  Journal of Pediatric Hematology Oncology. J Pediatr Hematol Oncol, 2003; 25(12):978-81.

Assanasen C, Mineo C, Seetharam D, Yuhanna I, Marcel Y, Connelly M, Williams D, de la Llera-Moya M, Shaul P, Silver D.  Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-B1 mediate HDL-initiated signaling.  J Clin Invest,  2005; 115(4):969-977.

Fine R, Shah S, Moulton T, Yu I, Fogelman D, Richardson M, Burris H, Samuels B, Assanasen C, Gorroochurn P, Hibshoosh H, Orjuela M, Garvin J, Goldman F, Dubovsky D, Walterhouse D, Halligan G.  Androgen and c-Kit receptors in desmoplastic small round cell tumors resistant to chemotherapy: novel targets for therapy.  Cancer Chemother Parmacol, 2007; 59 (4): 429-37.

Petty M, Cmelak A, Johnson M, Sinatra R, Jennings M.  Chapter in Textbooks of Uncommon Cancer.  Edited by D. Raghaven, et al.  John Wiley and Sons Ltd.  1999.

Granger M, Wright W, Shay J.  Telomerase in Cancer and Aging.  Critical Reviews in Hematology-Oncology, 2002; 41 (1): 29-40.

Ran S, He J, Huang X, Soares M, Scothorn D & Thorpe PE. Anti-Tumor Effects of a Monoclonal Antibody Directed against Phosphatidylserine on Tumor Blood Vessels in Mice. Clin Cancer Res 2005; 11(4): 1551-62.

Scothorn DJ, Schwartz D, Price C, Buchanan GR, Sarniak I, Shurney W, Fallon R, Chu J-Y, Pegelow C, Wang W, Resar L, Berman B, Adamkiewicz T, Hsu L, Brunson G, Casella J, Ohene-Frempong K, Smith K, Mahoney D & DeBaun MR. Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years following initial stroke. J Pediatr 2002; 140: 348-54.

Scothorn DJ & Butler MG. How common is precocious puberty in patients with Williams Syndrome? Clin. Dysmorphology 1997; 6: 91-93.

Jones JG, Hackett NR, Halladay JT, Scothorn DJ, Yang CF Ng WL & DasSarma S. Analysis of insertion mutants reveals two new genes in the pNRC100 gas vesicle gene cluster of Halobacterium halobium. Nucleic Acids Res 1989; 17: 7785-93.

Journeycake JM, Quinn CT, Miller KL, Zajac JL and Buchanan GR.  Catheter-related deep venous thrombosis in children with hemophilia.  Blood  2001; 98: 1727-1731.

Journeycake JM, Buchanan GR,  Miller KL, Anderson A, and Finnegan M.  Arthroscopic synovectomy in children and adolescents with hemophilia.  J Pediatr Hematol Oncol  2003; 25: 726-731.

Bowers DC, Aquino VA, Leavey PJ, Journeycake JM, et al.  Phase I study of oral cyclophosphamide and oral topotecan for children with recurrent or refractory solid tumors.  Pediatr Blood Cancer 2004; 42: 93-98.

Ewenstein BM, Valentino LA, Journeycake JM, Tarantino MD, Shapiro AD, Blanchette VS, et al.  Consensus recommendations for use of central venous access devices in haemophilia.  Haemophilia 2004; 10: 1-20.

Journeycake JM, Eshelman DA, and Buchanan GR.  Post-thrombotic syndrome is uncommon in childhood cancer survivors.   J Pediatr 2006; 148: 275-277.

Journeycake JM and Buchanan GR.  Catheter-related deep venous thrombosis and other catheter complications in children with cancer.  J Clin Oncol. 2006; 24: 4575-80.

Di Paola J, Aledort L, Britton H, Carcao M, Grabowski E, Hutter J, Journeycake J, Kempton C, Leissinger C.  Application of current knowledge to the management of bleeding events during immune tolerance induction.  Haemophilia 2006; 6: 591-5

FELLOWS' FUNDED GRANTS:  2004-PRESENT

 

Pediatric Hematology/Oncology

Competitive Grant Applications submitted by Fellows

2004 to Current

 

Fellow/Mentor

Grantor

Type

Dates

Funded:

Crary/ Buchanan

Amgen Oncology Institute

Hem/Onc Fellowship Award

7/1/05 – 6/30/06

Yes –  $40,000

Crary/Buchanan

Hemophilia and Thrombosis Research Society

Research Competition

5/1/05 – 4/30/06

Yes –  $5,000

Collier/ Tomlinson

American Society of Clinical Oncology (ASCO)

Young Investigator Award

7/1/04 – 6/30/05

Yes –  $35,000

Collier/Tomlinson

American Assoc. for Cancer Research

Research Fellowship

7/1/04 – 6/30/05

Yes –  $35,000

Wright/Winick

ASCO

Young Investigator Award

7/1/06 – 6/30/07

No

Wright/Winick

Children’s Cancer Research Fund

Clinical Research

8/1/06 – 7/31/07

No

Wright/Winick

Alex’s Lemonade Stand Childhood Cancer Foundation

Young Investigator Award

7/1/06 – 6/30/07

No

Wright/Winick

Lance Armstrong Foundation

Clinical Research

1/1/07 – 12/31/07

No

Wickiser/Tomlinson

Amgen Oncology Institute

Hem/Onc Fellowship Award

7/1/05 – 6/30/06

No

Wickiser/Tomlinson

American Assoc. for Cancer Research

Research Fellowship

7/1/06 – 6/30/07

No

Wickiser/Tomlinson

ASCO

Young Investigator Award

7/1/06 – 6/30/07

No

Slone/Winick

Hope Street Kids

Clinical Research

7/1/07 – 6/30/09

No

Slone/Winick

American Society of Clinical Oncology (ASCO)

Young Investigator Award

7/1/07 – 6/30/08

Yes – $50,000

Slone/Winick

Children’s Cancer Research Fund

Clinical Research

8/1/06 – 7/31/07

No

Slone/Winick

Alex’s Lemonade Stand Childhood Cancer Foundation

Young Investigator Award

7/1/07 – 6/30/09

No

Slone/Winick

Children’s Cancer Fund (CCF)

Pediatric Oncology Research

5/1/07 – 10/30/08

Yes - $50,000

Niece/Rogers

Amgen Oncology Institute

Hem/Onc Fellowship Award

7/1/07 – 6/30/08

Yes - $40,000

Niece/Rogers

St. Baldrick’s Foundation

Pediatric Oncology Research Fellowship

7/1/06 – 6/30/08

No

Litten/Tomlinson

St. Baldrick’s Foundation

Pediatric Oncology Research Fellowship

7/1/06 – 6/30/08

Yes – $105,000

Fellow/Mentor

Grantor

Type

Dates

Funded:

 

 

 

 

 

Litten/Tomlinson

Hope Street Kids

Clinical Research

7/1/07 – 6/30/09

No

Klesse/Parada

Children’s Brain Tumor Foundation (CBTF)

Laboratory Research

12/1/07 – 11/30/09

No

Hatley/Olson

Physician Scientist Training Program (PSTP)

Laboratory Research

7/1/07 – 6/30/09

Yes  (relinquished when PSDP was awarded)

Hatley/Olson

Pediatric Scientist Development Program (PSDP)

Research Fellowship

7/1/07 – 6/30/09

Yes - $175,000

Tarango/Shaul

Physician Scientist Training Program (PSTP)

Laboratory Research

9/1/08 – 8/31/10

Yes - $100,000