Publications from TORS Investigators

2011

• Bastarrachea, R.A., Veron, S.M., Vaidyanathan, V., Garcia-Forey, M., Voruganti, V.S., Higgins, P.B., Parks, E.J. 2011. Protocol for the measurement of fatty acid and glycerol turnover in vivo in baboons. J. Lipid Res. In press. PMCID: PMC - Journal in Process.
• Chuang, J.C., Perrello, M., Sakata, I., Osborne-Lawrence, S., Savitt, J.M., Lutter, M. , Zigman, J.M. 2011. Ghrelin mediates stress-induced food-reward behavior in mice. J. Clin. Invest. 121:2684-2692. PMCID: PMC - Journal in Process.
• Browning, J.D. , Baker, J.A., Rogers, T., Davis, J., Satapati, S., Burgess, S.C. 2011. Short-term weight loss and hepatic triglyceride reduction: evidence for a metabolic advantage with dietary carbohydrate restriction. Am. J. Clin. Nutr. 93:1048-1052. PMCID: PMC3076656.
• Dimitrov, I.E., Douglas, D., Ren, J., Smith, N.B., Webb, A.G., Sherry, D. , Malloy, C.R. 2011. In vivo determination of human breast fat composition by ¹H magnetic resonance spectroscopy at 7 T. Magn. Reson. Med . In press. PMCID: PMC - Journal in Process.
• Donato, J., Jr., Cravo, R.M., Renata, F., Gautron, L., Scott, M.M., Lachey, J., Castro, I.A., Margatho, L.O., Lee, S., Lee, C., Richardson, J.A., Friedman, J., Chua., Jr. S., Coppari, R. , Zigman, J.M. , Elmquist, J.K. , Elias, C.F. 2011. Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. J. Clin. Invest. 121:355-368. PMCID: PMC3007164.
• Fukuda, M., Williams, K.W., Gautron, L., Elmquist, J.K. 2011. Induction of Leptin Resistance by Activation of cAMP-Epac Signaling. Cell Metab. 13:331-339. PMCID: PMC - Journal in Process.
• Gautron, L., Sakata, I., Udit, S., Zigman, J.M. , Wood, J.N., Elmquist, J.K. 2011. Genetic tracing of Nav1.8-expressing vagal afferents in the mouse. J. Comp. Neurol. 519:3085-3101. PMCID: PMC - Journal in Process.
• Gautron, L., Elmquist, J.K . 2011. Sixteen years and counting: an update on leptin in energy balance. J. Clin. Invest. 121:2087-2093. PMCID: PMC3104762.
• Holland, W.L. , Miller, R.A., Wang, Z.V., Sun, K., Barth, B.M., Bui, H.H., Davis, K.E., Bikman, B.T., Halberg, N., Rutkowski, J.M., Wade, M.R., Tenorio, V.M., Kuo, M.-S., Brozinick, J.T., Zhang, B.B.. Birnbaum, M.J., Summers, S.A., Scherer, P.E. 2011. Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nat. Med. 17: 55-63. PMCID: PMC Journal in Process.
• Kim, K.W., Sohn, J.W., Kohno, D., Xu, Y., Williams, K., Elmquist, J.K. 2011. SF-1 in the ventral medial hypothalamic nucleus: A key regulator of homeostasis. Mol. Cell Endocrinol. 336:219-223. PMCID - PMC3057357.
• Kim, K.W., Zhao, L., Donato, J., Jr,, Kohno, D., Xu, Y., Elias, C.F., Lee, C., Parker, K.L. , Elmquist, J.K. 2011. Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus. Proc. Natl. Acad. Sci. USA. In press. PMCID: PMC Journal in Process.
• Kozlitina, J., Boerwinkle, E., Cohen, J.C. , Hobbs, H.H. 2011. Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance. Hepatology. 53:467-474. PMCID: PMC3057507.
• Mochizuki, T., Arrigoni, E., Marcus, J.N., Clark, E.L., Yamamoto, M., Honer, M., Borroni, E., Lowell, B.B., Elmquist, J.K . , Scammell, T.E. 2011. Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice. Proc. Natl. Acad. Sci. USA. 108:4471-4476. PMCID: PMC3060231.
• Perello, M., Scott, M.M., Sakata, I., Lee, C.E., Chuang, J.C., Osborne-Lawrence, S., Rovinsky, S.A., Elmquist, J.K . , Zigman, J.M. 2011. Functional implications of limited leptin receptor and ghrelin receptor co-expression in the brain. J. Comp. Neurol. In press. PMCID: PMC Journal in Process.
• Ramirez, R., Cohen, J.C. , Hobbs, H.H. , Browning, J.D. 2011. Hepatology. 54:736-737. PMCID: PMC Journal in Process.
• Ren, J., Sherry, D. , Malloy, C.R. 2011. Noninvasive ¹H MRS detection of acetyl metabolism in human skeletal muscle. Magn. Reson. Med. In press. PMCID: PMC - Journal in Process.
• Rios, J. , Shastry, S., Jasso, J., Hauser, N., Garg, A., Bensadoun, A., Cohen, J.C., Hobbs, H.H. 2011. Deletion of GPIHBP1 causing severe chylomicronemia. Hum. Mutat. In Press.
• Rossi, J., Balthasar, N., Olson, D., Scott, M., Berglund, E.D. , Lee, C.E., Choi, M.J., Lauzon, D., Lowell, B.B., Elmquist, J.K . 2011. Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell. Metab. 13:195-204. PMCID: PMC3033043.
• Scott, M.M., Marcus, J.N., Pettersen, A., Birnbaum, S.G., Mochizuki, T., Scammell, T.E., Nestler, E.J. , Elmquist, J.K., Lutter, M. 2011. Hcrtr1 and 2 signaling differentially regulates depression-like behaviors. Behav. Brain Res. 222:289-294. PMCID: PMC - Journal in Press.
• Scott, M.M., Williams, K.W., Rossi, J., Lee, C.E., Elmquist, J.K. 2011. Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice. J. Clin. Invest. 121:2413-2421. PMCID: PMC3104740.
• Sohn, J.W., Xu, Y., Jones, J.E., Wickman, K., Williams, K.W., Elmquist, J.K. 2011. Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron. 71:488-497. PMCID: PMC - Journal in Process.
• Sun, K., Kusminski, C.M., Scherer, P.E. 2011. Adipose tissue remodeling and obesity. J. Clin. Invest. 121:2094-2100. PMCID: PMC3104761.
• Vialou, V., Cui, H., Perello, M., Mahgoub, M., Yu, H.G., Rush, A.J., Pranav, H., Jung, S., Yangisawa, M., Zigman, J.M., Elmquist, J.K., Nestler, E.J. , Lutter, M. 2011. A role for ΔFosB in calorie restriction-induced metabolic changes. Biol. Psychiatry. In press. PMCID: PMC - Journal in Process.
• Wang, J., Grishin, N., Kinch, L., Cohen, J.C. , Hobbs, H.H. , Xie, X.S. 2011. Sequences in the nonconsensus nucleotide-binding domain of ABCG5/ABCG8 required for sterol transport. J. Biol. Chem. 286:7308-7314. PMCID: PMC3044987.
• Williams, K.W., Scott, M.M., Elmquist, J.K. 2011. Modulation of the central melanocortin system by leptin, insulin, and serotonin: Co-ordinated actions in a dispersed neuronal network. Eur. J. Pharmacol. 660:2-12. PMCID: PMC3085544.