Other Projects

Post-acute care in the elderly: the role of long-term acute care hospitals

Principal Investigator: Anil N. Makam, M.D., M.A.S.
Funding Source: National Institute on Aging
Objective: This 5-year K23 grant will examine variation and outcomes of care of comparably sick elderly individuals discharged to long-term acute care hospitals (LTACs) versus those discharged to skilled nursing facilities. It will use national Medicare data, EHR data from a regional  hospital network, and prospective data collection to understand patterns of post-acute care, the patient, provider and system factors influencing LTAC use, and their associated clinical outcomes and costs.

The role of long-term acute care hospitals in caring for non-ventilated older adults

Principal Investigator: Anil N. Makam, M.D., M.A.S.
Funding Source: National Institute on Aging
Objective: This GEMSSTAR R03 grant will use national Medicare data to: 1) examine why hospitalized older adults are discharged to long-term acute care hospitals (LTAC) versus remaining in the acute care hospital, the principal alternate to LTACs; and 2) comparatively assess the effectiveness of LTACs versus continued care in the acute care hospital on outcomes, utilization, costs, and spending.  

Building Capacity for Effective, Equitable Implementation of a Social-Health Information Exchange for the Underserved in Dallas

Principal Investigator: Oanh Kieu Nguyen, M.D., M.A.S.
Funding source: Program for Development and Evaluation of Model Community Health Initiatives in Dallas (PDEMCHID)
Objective: This community-based research pilot study will provide Parkland and Dallas community partners with critical information for successful implementation of a social-health information exchange portal to better tailor existing health and social services to client needs, coordinate care across sectors, and promote delivery of complementary health and social services through use of the information exchange.

Assessing the Comparative Effectiveness of Scheduled Versus Emergency Dialysis in End-Stage Renal Disease

Principal Investigator: Oanh Kieu Nguyen, M.D., M.A.S.
Funding source: UT Southwestern Center for Translational Medicine Translational Pilot Program
Objective: This translational research pilot study will establish a cornerstone of the foundational evidence base that is needed for a robust, definitive cost-effectiveness analysis of dialysis strategies for ESRD. This knowledge will enable the translation of evidence into policy to enable universal access and use of the most cost-effective and evidence-based dialysis strategy for all individuals with ESRD.

Reducing Readmissions and Improving Outcomes In HIV-Infected Patients

Principal Investigator: Ank E. Nijhawan, M.D., M.P.H., M.S.C.S.
Funding source: National Institute of Allergy and Infectious Diseases
Objective: This K23 project aims to better predict 30-day readmissions in HIV-infected patients utilizing electronic health data, to understand reasons for readmissions using both quantitative and qualitative methods and to reduce 30-day readmissions through a multi-component intervention.‚Äč

Improving Outcomes for Older Veterans with Chronic Back Pain and Depression

Principal Investigator: Una E. Makris, M.D., M.S.C.S.
Funding Source: VA Health Services Research and Development
Objective: During this VA HSRD CDA-2 award Dr. Makris will develop a non-pharmacological, behavioral intervention, using stakeholder input, that will be delivered by health coach via telephone and then conduct feasibility pilot testing to improve outcomes in older Veterans with chronic back pain and comorbid depression.

Comparative effectiveness of patient-centered strategies to improve pain management and opioid safety for Veterans

Principal Investigator (Site-PI at Dallas VA): Una E. Makris, M.D., M.S.C.S.
Funding Source: PCORI
Objective: The overall objective of this research is to improve effectiveness and safety of pain management among patients with chronic pain. This 12-month pragmatic randomized trial will compare two systems of care strategies, which differ substantially in comprehensiveness and resource intensity, to improve pain and reduce opioid use among Veterans.

Safety and Effectiveness of Metformin

Principal Investigator: Carlos Alvarez, Pharm.D.
Funding Source: National Institute of Diabetes and Digestive and Kidney Diseases
Objective: This pharmacoepidemiology study will use national VA data to evaluate the safety and effectiveness of metformin use v. other drugs among patients with diabetes and chronic kidney disease.

Predicting diabetes risk using glucose data

Principal Investigator: Michael Bowen, M.D., M.P.H.
Funding Source: National Institute of Diabetes and Digestive and Kidney Diseases
Objective: This K23 award will harness data in the EMR to detect patterns of abnormal random glucose that identify patients with suspected but undiagnosed diabetes/pre-diabetes, conduct a prospective diabetes/pre-diabetes screening study in those at high risk, and develop EMR-enabled decision support to flag and prompt definitive testing of those at high risk.

Cardiovascular risks of prescription amphetamine use in adults

Principal Investigator: Arthur Westover, M.D., M.P.H.
Funding Source: National Institute of Drug Abuse
Objective: This K08 award will conduct a pharmacoepidemiology study to assess the impact of amphetamine prescription on long term cardiovascular events using a national VA database of 8 million patients