Leadership

James Brugarolas, M.D., Ph.D.

Program Leader
James Brugarolas

James Brugarolas, M.D., Ph.D., received his medical degree from the University of Navarra, Spain (1993), and his Ph.D. from the Massachusetts Institute of Technology (1998). He trained in internal medicine at Duke University Medical Center and completed a fellowship in oncology at a combined program of the Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Massachusetts General Hospital in 2003. He was an instructor at Harvard Medical School until 2006, when he was recruited by UT Southwestern Medical Center to create a program in kidney cancer. Discoveries from his laboratory have led to a new classification of kidney cancer, the identification of a new familial kidney cancer syndrome, and the development of the first animal model to reproduce the genetics, biology, and treatment responsiveness of kidney cancer in patients.

Dr. Brugarolas is a member of the American Society for Clinical Investigation and has received numerous awards including a V Scholar Award (V Foundation), a Research Scholar Award (American Cancer Society), and a Claudia Adams Barr Award for Innovative Cancer Research (Dana Farber Cancer Institute, Harvard Medical School). He has served as a member of the Scientific Advisory Board of kidney cancer programs at several NCI-designated cancer centers. In addition, he has served in study sections and ad hoc review panels of the National Cancer Institute, the American Cancer Society, and the U.S. Army Medical Research Command.

Co-Leaders

James Amatruda, M.D., Ph.D.

Co-Leader, Pediatrics
Dr. James Amatruda

James F. Amatruda, M.D., Ph.D., received his M.D. and Ph.D. degrees from Washington University in St. Louis, followed by a residency in Internal Medicine at Brigham and Women's Hospital in Boston. He then completed a fellowship in Medical Oncology at the combined Dana-Farber Cancer Institute/Massachusetts General Hospital Program. In 2005 he joined the faculty at UT Southwestern, where he is Associate Professor of Pediatrics, Molecular Biology, and Internal Medicine, and an attending physician in the Pauline Allen Gill Center for Cancer and Blood Disorders. Dr. Amatruda holds the Nearburg Family Professorship in Pediatric Oncology Research. His laboratory studies the biologic basis of childhood genitourinary cancers, including germ cell tumors and Wilms tumors of the kidney, using a combination of genomic analysis and zebrafish genetic models.

Bijal Balasubramanian, M.B.B.S., Ph.D.

Co-Leader, Epidemiology
Bijal Balasubramanian

Bijal Balasubramanian, M.B.B.S., Ph.D., completed her medical training in 1996 at the University of Pune, N.D.M.V.P. Samaj’s Medical College (Nashik, India). In 2008, she received a Ph.D. from the Rutgers School of Public Health. Currently, she is a faculty member in the Division of Epidemiology, Human Genetics & Environmental Science at the University of Texas Health Science Center at Houston – School of Public Health. Her expertise is in the application of epidemiological and mixed-methods research to understand determinants of quality of health care; she has a particular interest in cancer.

Richard Bruick, Ph.D.

Co-Leader, Basic Research
Richard Bruick

Richard Bruick, Ph.D., received an undergraduate degree in chemistry from the University of North Carolina at Chapel Hill (1991) and a Ph.D. in macromolecular and cellular structure and chemistry from Scripps Research Institute (1998). After postdoctoral training with Steve McKnight, Ph.D., he joined the faculty at UT Southwestern Medical Center. Dr. Bruick has made fundamental discoveries about the regulation of HIF-2 leading to the development of a HIF-2 inhibitor.

Payal Kapur, M.D.

Co-Leader, Pathology
Payal Kapur

Payal Kapur, M.D., is the Medical Director of Pathology at Parkland Health & Hospital System and the reference GU pathologist at UT Southwestern. Dr. Kapur completed her medical education at the University College of Medical Sciences (New Delhi, India) in 1997. She trained in pathology at both Maulana Azad Medical College and UT Southwestern Medical Center. Her research is focused on characterizing adult genitourinary tumors and the development of diagnostic, prognostic, and predictive biomarkers. She is responsible for developing a clinical test to evaluate the status of BAP1 and PBRM1 in renal cancer, which underlies a modern classification of the disease.

Nathan Kim, M.D., Ph.D.

Co-Leader, Radiation Oncology
Nathan Kim

Nathan Kim, M.D., Ph.D., received a master’s degree in biomedical engineering from Johns Hopkins University and a combined M.D./Ph.D. from Boston University (2001). He completed his residency training in radiation oncology at Vanderbilt University Medical Center (2006), where he served as chief resident. He joined the Department of Radiation Oncology at UT Southwestern Medical Center in 2010. Dr. Kim specializes in the treatment of genitourinary cancers and is interested in the optimization of stereotactic ablative radiotherapy (SABR) techniques.

Ivan Pedrosa, M.D.

Co-Leader, Radiology
Ivan Pedrosa

Ivan Pedrosa, M.D., is the Director of MRI imaging at UT Southwestern Medical Center. Dr. Pedrosa received his medical degree from Universidad Complutense (Spain, 1994) and completed residency training at Hospital Universitario San Carlos in radiology. He did fellowships at Jackson Memorial and Beth Israel Deaconess hospitals and joined UT Southwestern in 2011. He is an internationally recognized expert in kidney cancer and serves on the National Cancer Institute's Renal Cancer Task Force. He has implemented protocols for the evaluation of localized and metastatic kidney tumors and runs an NIH-funded translational research program that applies novel MRI techniques for the phenotypic characterization of renal tumors to assess histological subtype, nuclear grade, and angiogenesis.

Arthur Sagalowsky, M.D.

Co-Leader, Urology
Arthur Sagalowsky

Arthur I. Sagalowsky, M.D., received his medical degree from Indiana University Medical School (1973), where he continued his training in general surgery (1973-1975) and urology (1975-1978). Subsequently, he was an American Urological Association Research Scholar and a post-doctoral research fellow in clinical pharmacology at UT Southwestern Medical Center (1978-1980). In 1980, he joined the faculty in Urology, where he rose through the ranks to Professor. He is engaged in full-time academic practice of urologic oncology and has vast surgical experience in the management of patients with locally advanced and complex kidney cancers. He has actively participated in clinical trials and translational research in kidney cancer for more than 33 years.