Clinical Trials

Localized Renal Cancer      

Success of Active Surveillance in Patients with Untreated Small Renal Masses with the Option of Delayed Treatment
Principal Investigator: Vitaly Margulis, M.D.
Status: Recruiting
Contact: Allison Beaver, R.N.
Phone: 214-645-8789
allison.beaver@utsouthwestern.edu

A Phase II Trial of Stereotactic Ablative Body Radiation Therapy (SABR) for Patients with Primary Renal Cancer (RCC)
Principal Investigator: Raquibul Hannan, M.D., Ph.D.
Status: Recruiting
Contact: Kristi Louder 
Phone: 214-648-5779
kristi.louder@utsouthwestern.edu 

Advanced or Metastatic Renal Cancer

Immunotherapy (IL2 and checkpoint inhibitors)

A Randomized, Open-Label, Phase III Study of Nivolumab (BMS-936558) vs. Everolimus in Subjects with Advanced or Metastatic Clear-Cell Renal Carcinoma Who Have Received Prior Anti-Angiogenic Therapy
Principal Investigator: James Brugarolas, M.D., Ph.D.
Status: Ongoing, but completed recruitment
Contact: Dendra Von Merveldt, R.N.
Phone: 214-645-8789
dendra.vonmerveldt@utsouthwestern.edu

A Phase II Trial of High Dose IL-2 and Stereotactic Ablative Body Radiation Therapy (SABR) for Patients with Metastatic Clear Cell Renal Cell Cancer (mRCC)
Principal Investigator: Raquibul Hannan, M.D., Ph.D.
Status: Recruiting
Contact: Kristi Louder
Phone: 214-648-5779
kristi.louder@utsouthwestern.edu

A Phase III, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab versus Sunitinib Monotherapy in Subjects with Previously Untreated, Advanced or Metastatic Renal Cell Carcinoma
Principal Investigator: James Brugarolas, M.D., Ph.D.
Status: Estimated Opening Date – end of March 2015
Contact: Dendra Von Merveldt, R.N.
Phone: 214-645-8789
dendra.vonmerveldt@utsouthwestern.edu 

Molecularly Targeted Therapies

A Phase I, Dose-Escalation Trial of PT2385 Tablets in Patients with Advanced Clear Cell Renal Cell Carcinoma
Principal Investigator: Kevin Courtney, M.D., Ph.D.
Status: Estimated Opening Date – end of March 2015
Contact: Mora Kim, R.N.
Phone: 214-648-4987
mora.kim@utsouthwestern.edu