Healthy Volunteer Trials

Note: Not every study site accepts healthy volunteers. Please check with the listed study contact for the clinical trial to verify whether a location is accepting healthy volunteers.

* Metabolic Abnormalities in Patients with Inborn Errors of Cobalamin Metabolism[Double Quote]

A Double-Blind, Placebo-Controlled, Single Ascending Intravenous Infusion Study of rHIgM22 in Patients with Multiple Sclerosis

A Longitudinal Case-Control Study to Collect Clinical Data and Biologic Specimens for Research into Various Chronic Diseases

A Longitudinal Case-Control Study to Collect Clinical Data in Pediatric Central Nervous System Demyelinating Diseases

A Longitudinal Study of Patients Diagnosed With or at Increased Risk for Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorder

A Longitudinal, Case-Control Study to Collect Medical and Epidemiological Data and Blood Samples for Research Into the Causes of Multiple Sclerosis and Selected Demyelinating Diseases

A Multicenter, Open-Label, Randomized Study of the Contraceptive Efficacy and Safety of Amphora(TM) Gel Compared to Conceptrol(RegisteredTM) Vaginal Gel

A Phase 3, Multi-Center, open-Label Study of a Levonorgestrel-Releasing Intrauterine System for Long-Term, Reversible contraception

A Research Depository of Normal and Neoplastic Human Tissues

A Search for Optimally Bioavailable Calcium-Magnesium Supplement with Reduced Cardiovascular Risk

A Study of Physical and Metabolic Abnormalities in Patients with Lipodystrophy and Dyslipidemias and Their Relatives

A phase 2, open-label, clinical trial of fluoxetine, a selective serotonin reuptake inhibitor, in the treatment of pulmonary arterial hypertension


ASPREE Study: Asprin in Reducing Events in the Elderly

Adduct Dipstick for Diagnosis of Acetaminophen Toxicity

Adherence to Disease-Modifying Therapies in Pediatric Multiple Sclerosis

Adjunctive Smart Phone Based Smoking Cessation Treatment

An Observational Study of Hepatitis C Virus in Pregnancy (HCV)

Analysis of endothelial cells in rheumatoid arthritis

Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Study

Assessment of Calcium Metabolism, Parathyroid Function and Vitamin D Status in Disorders of Mineral Metabolism


Blood Repository for Food Allergic Patients

Body fluids, tissue and data repository development from women with polycystic ovary syndrome (PCOS)


Calcium Intake and the Risk of Nephrolithiasis

Childhood Cancer Survivor Study Expansion: Long-Term Follow-up Study

Clinical Assessment of the Performance of a Fractional CO2 Laser System (Fraxel Repair Laser) intended for treatment of perioral rhytides/wrinkles

Clinical Development of MR Spectroscopy and Imaging in Brain Cancers

Clinical and Immunological Studies of Vitiligo

Coarctation of the Aorta: Long Term Outcomes and Comorbidities

Cognitive Changes in Demylinating Diseases (A Longitudinal Study of Cognitive Assessment in patients with Multiple Sclerosis, Acute Disseminated Encephalomyelitis, Transverse Myelitis, Neuromyelitis Optica, Neurosarcoidosis and Optic Neuritis)

Cognitive and Sensorimotor Mechanisms of Autism Spectrum Disorder (ASD)

Comparison of Endorectal Coil Magnetic Resonance Imaging Versus Pelvic Digital Coil Resonance Magnetic Imaging at 3 Tesla for Detection and Local Staging of Prostate Cancer

Comparison of Smartphone Application-Based Vital Sign Monitors to Devices Used in Clinical Practice

Correction of B0 inhomogeneity Induced by Orthodontic Appliances in MRI

Customized Laser Ablation: Comparing Results of LADAR Vision Wavelight and VISX Platforms

Dallas Regional Autoimmune Disease Registry

Database Registry for Psychotic Disorders (DRPD)

Database of Medical Information from Healthy Volunteers

Database registry to Examine Brain Connections and Brain Function in Mental Disorders and Neural Network Biomarkers for Relational Memory and Psychosis in Schizophrenia

Detection of Impaired Intrinsic Bone Strength in vivo by Ultrasound Critical Angle Reflectometry

Developing a self-persuasion intervention promoting adolescent HPV vaccination

Development of a Multi-modality Non-Radiologic Image Repository and Registry

Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) (Protocol NIH N01-DK-6-2203)

Effect of Proton Pump Inhibitor on Bioavailability of Effervescent Calcium Magnesium Citrate

Effect of lactation on ectopic lipid after gestational diabetes

Effects of Dietary Potassium on WNK1, Blood Pressure, and Insulin Metabolism

Elucidation of the Role of Fat in Abnormally Acidic Urine in Patients with Nephrolithiasis

Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis

Establishing a Database on the Plasma Level of Klotho in Humans, in Health and Disease

Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)

Evaluation of System Enhancements for Magnetic Resonance Imaging Hardware and Software in a Clinical Setting

Evaluation of Thrombin Generation in Children with Venous Thromboembolism

Evaluation of the biochemical and Biophysical Properties of Meibomian lipid Samples collected From Meibomian Glands of normal Donors and Dry Eye Patients

Exercise in Burn Survivors

Expression of co-inhibitory receptors in inflammatory skin disease

Factors associated with adolescent HPV vaccine use in UTSW and Parkland affiliated clinics

Family Studies of Sensorimotor and Neurocognitive Heterogeneity in Autism Spectrum Disorders (ASD)

Fever related illness non-urgent visit costs to a large pediatric emergency department.

Finding the Causes of Rare Skin Diseases

Gene Discoveries in Subjects with Crohns Disease of African Descent

Genetic Determinations of Familial Chest Wall Abnormalities

Genetic Studies in Addiction

Genetic Variation in a Multi-Ethnic Population

Genetic and Biomarker Study of Alzheimer's Disease

H+-ATPase B-subunit Dysfunction and Calcium Nephrolithiasis

H-29892, Case Ascertainment for Epidemiologic Studies of Childhood Cancers and Hematological Conditions

Health Topics Survey

Hippocampal Neurogenesis in Human Subjects (Pilot Study)

Hypertension and Antihypertensive Therapy in Elderly Women

INSPPIRE to Study Acute Recurrent and Chronic Pancreatitis in Children

Icariin to Prevent Corticosteroid-related Memory Changes

Immunologic and Genetic Profiles in Subsets of Morphea Patients

Integrating Evidence Based Pediatric Pre-Hospital Protocols into Practice

Investigating the Feasibility of Using Rapid Cine-MRI for Monitoring Moving and Deforming Tumors

LDL and Cholesterol Metabolism

Leveraging Technology To Provide The Next Generation of Clinical Connectivity

Micro-RNA Expression Profiling of Patients with Primary Immunodeficiency Diseases.

Mild Cognitive Impairment: Cerebrovascular Dysfunction and Exercise Training

Molecular Basis of Cholesterol Metabolism and Selected Other Genetic Disorders

Molecular Characteristics of Tumor Cells

Molecular Studies of Cutaneous Lupus

Molecular mechanisms of renal phosphate transport in human health and disease

Mutational Spectrum of Anterior Segment ophthalmic disorders

Nephrolithiasis in Patients with Primary Hyperparathyroidism

Neural mechanisms of aldosterone-induced insulin resistance.

Neurobiology of Alzheimer's Disease and Aging - (Genetics of Dementing Brain Diseases)

Neuroimaging to predict coma emergence and recovery: A pilot study (NICER pilot)

Neutrophil Function in Cystic Fibrosis Patients

Non-Invasive Evaluation of Brain Oxygen Metabolism Using Magnetic Resonance Imaging

Non-invasive Visualization by Diagnostic Ultrasonography of the Radial Artery in Vivo of Normal Subjects and Subjects with Chronic Kidney Disease

Novel Treatment of Emotional Dysfunction in PTSD


Parkinsons Disease biomarkers program

Parkland-UT Southwestern PROSPR Center: Colon cancer screening in a safety net

Pathophysiology of Gouty Diathesis and Uric Acid Nephrolithics: Role of Insulin Resistance

Pathophysiology of Uric Acid Nephrolithiasis

Pharmacologic MRI in Cocaine-addiction

Phase I Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Topical GSK 1278863 in Healthy Volunteers and Diabetic Patients, and Repeat Doses of GSK 1278863 in Diabetic Patients for the Treatment of Diabetic Foot Ulcer

Philips Pivotal Clinical Trial for MRI-guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids

Physiological, Neural and Cognitive Bases of Age-Related Working Memory Change

Plasma ceramides and correlation with adiponectin levels in children and adolescents with type 2 diabetes.

Potential Role of Gastrointestinal Alkali Loss in Patients with Uric Acid Nephrolithiasis

Potential Role of Gastrointestinal Microflora in Increased Acid Production in Patients with Uric Acid Nephrolithiasis

Preventing Perinatal Depression (PRE-D): Developing Tools and Interventions

Procurement of Patient and Control Blood Samples for Deposit in a Cell/DNA Repository to Facilitate the Study of Disorders of Mineral Metabolism

Proteomic Changes in the Aging Tear Film

Protocol HVTN 505: Phase 2b, randomized, placebo-controlled test-of-concept trial to evaluate the safety and efficacy of a multiclade HIV-1 DNA plasmid vaccine followed by a multiclade HIV-1 recombinant adenoviral vector vaccine in HIV-uninfected, adenovirus type 5 neutralizing antibody negative, circumcised men and male-to-female (MTF) transgender persons, who have sex with men

Psychiatry Clinical Research Infrastructure (P-CRI) Healthy Controls Database

Quantification of Volumetric Pulmonary Perfusion Using 3D Arterial Spin Labeled Perfusion MRI

Registry and Biorepository for the study of Inflammatory Bowel Disease

Regulation of Renal Calcium Transport by Acid-Base and Magnesium

Representation of Facial Identity and View-point in the Ventral Temporal Cortex

Research to Evaluate an Effective Community-level Intervention for Young Black Men Who Have Sex with Men

Risk Factors Underlying Increased Susceptibility and Severity of Lupus Nephritis

Role of Gut Microbiota in the Development of Metabolic Syndrome among Childhood Cancer Survivors

Role of Intestinal Microbiota in Children with Intestinal Failure and Bacterial Overgrowth

SPRINT-MS (NN102) "A randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability and activity of ibudilast (MN-166) in subjects with progressive multiple sclerosis"

Serum Levels of Potential Biomarkers for Diabetic Retinopathy and Age-related Macular Degeneration

Shortness of Breath During Exertion in Obesity

Spinal Muscular Atrophy (SMA) Biomarkers in the Immediate Postnatal Period of Development

TDCS Enhanced Stroke Recovery and Cortical Reorganization

Technology Development for Intracellular Metabolites at 7 Tesla

Technology development for optimization of MRI protocols in the clinical and research setting

The Effect of Maternal Habitus on Twin Growth and Evaluation of Fetal Anatomy

The Gut Microbiome in Psychiatric Illness

The Role Mitochondrial Dysfunction in Non-Alcoholic Fatty Liver Disease

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension

The University of Texas Southwestern Cardiology Clinical Research Database (CCRD) and Research Program

The effectiveness of contact lens care solutions on Pseudomonas biofilms formed in the presence of neutrophils

The relationship between brain iron accumulation and beta-amyloid deposition in middle-aged and older adults

UT Southwestern Liver Disease Repository and Registry

Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension

Whole Blood Platelet Aggregation in Chronic Kidney Disease on Aspirin and Clopidogrel Study

Zimmerman Program for the Molecular and Clinical Biology of VWD