Healthy Volunteer Trials

Note: Not every study site accepts healthy volunteers. Please check with the listed study contact for the clinical trial to verify whether a location is accepting healthy volunteers.

18F-AV-1451-A14 x Clinical Evaluation of 18F-AV-1451 Cause or effect? Untangling the relationship of amyloid and tau deposits to cognitive decline and Alzheimer[Single Quote]s disease in the Dallas Lifespan Brain Study

A Double-Blind, Placebo Controlled, Single Ascending Intravenous Infusion Study of rHIgM22 in Patients with Multiple Sclerosis Immediately Following a Relaspe

A Longitudinal Case-Control Study to Collect Clinical Data and Biologic Specimens for Research into Various Diseases

A Longitudinal Case-Control Study to Collect Clinical Data in Pediatric Central Nervous System Demyelinating Diseases

A Phase 3, Multi-Center, open-Label Study of a Levonorgestrel-Releasing Intrauterine System for Long-Term, Reversible contraception

A Research Depository of Normal and Neoplastic Human Tissues

A Search for Optimally Bioavailable Calcium-Magnesium Supplement with Reduced Cardiovascular Risk

A Study of Physical and Metabolic Abnormalities in Patients with Lipodystrophy and Dyslipidemias and Their Relatives

A comparison of the effects of Alcon DAILIES TOTAL1 and a control high oxygen permeable silicone hydrogel daily disposable contact lens, the ACUVUE TruEye, on the biology of the ocular surface and lid margin

A phase 2, open-label, clinical trial of fluoxetine, a selective serotonin reuptake inhibitor, in the treatment of pulmonary arterial hypertension


APEC14B1, Project: EveryChild- A Registry, Eligibility Screening, Biology and Outcome Study

ASPREE Study: Asprin in Reducing Events in the Elderly

Acute effects of phosphate and calcium intake on calciprotein particle (CPP) profile in healthy individuals and patients with chronic kidney disease: a pilot study

Adherence to Disease-Modifying Therapies in Pediatric Multiple Sclerosis

An Objective Blood Test from Stimulated Gene Expression for Classification and Outcome Assessment in Clinical Trials of Gulf War Illness

An Observational Study of Hepatitis C Virus in Pregnancy (HCV)

Analysis of endothelial cells in rheumatoid arthritis

Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Study

Assessing speech in patients with cleft palate using real-time MRI.

Assessment of Calcium Metabolism, Parathyroid Function and Vitamin D Status in Disorders of Mineral Metabolism

Assessment of Pupillary and Oculomotor Function in Multiple Sclerosis


Baseline and Post-Concussion Testing in Young Athletes Diagnosed with a Sports Related Concussion

Biological Substrates of Impaired Neurocognitive Functioning: Understanding the Late Effects of Surviving a Pediatric Brain Tumor

Biomarkers associated with Phelan-McDermid (22q13) Syndrome

Biospecimen procurement for immunologic correlates in cancer


Calcium Intake and the Risk of Nephrolithiasis

Cardiac Magnetic Resonance Imaging for Patients with High Cardiometabolic Risk Factors

Clinical Assessment of the Performance of a Fractional CO2 Laser System (Fraxel Repair Laser) intended for treatment of perioral rhytides/wrinkles

Clinical and Immunological Studies of Vitiligo

Cognitive and Sensorimotor Mechanisms of Autism Spectrum Disorder (ASD)

Collaboration on Neuroimmunology: Question, Understand, Educate, Restore x The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

Comparative Analysis of Chronobiological Changes in Burn, Trauma and Traumatic Brain Injury

Comparison of Endorectal Coil Magnetic Resonance Imaging Versus Pelvic Digital Coil Resonance Magnetic Imaging at 3 Tesla for Detection and Local Staging of Prostate Cancer

Comprehensive assessment of gait and balance in patients with neurologic disease.

Confounder-Corrected Quantitative MRI Biomarker of Hepatic Iron Content

Contribution of growth factor expression to post-stroke cortical plasticity- Pilot

Contributions of the Gut Microbiome to Anxiety Symptomatology

Corneal sensitivity and nerve fiber morphology in patients with obstructive sleep apnea.

Correction of B0 inhomogeneity Induced by Orthodontic Appliances in MRI

Customized Laser Ablation: Comparing Results of LADAR Vision Wavelight and VISX Platforms

DHREAMS: Diaphragmatic Hernia Research & Exploration; Advancing Molecular Science

Dallas Regional Autoimmune Disease Registry

Database Registry for Psychotic Disorders (DRPD)

Database of Medical Information from Healthy Volunteers

Database registry to Examine Brain Connections and Brain Function in Mental Disorders and Neural Network Biomarkers for Relational Memory and Psychosis in Schizophrenia

Defining the Tear Film Proteome

Developing a self-persuasion intervention promoting adolescent HPV vaccination

Development of a Multi-modality Non-Radiologic Image Repository and Registry

Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) (Protocol NIH N01-DK-6-2203)

Effect of Proton Pump Inhibitor on Bioavailability of Effervescent Calcium Magnesium Citrate

Effect of lactation on ectopic lipid after gestational diabetes

Effects of Dietary Potassium on WNK1, Blood Pressure, and Insulin Metabolism

Effects of Ghrelin on Sympathetic Nerve Activity in Humans

Elucidation of the Role of Calcium Sensor in Absorptive Hypercalciuria

Elucidation of the Role of Fat in Abnormally Acidic Urine in Patients with Nephrolithiasis

Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis

Establishing a Database on the Plasma Level of Klotho in Humans, in Health and Disease

Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)

Evaluation of System Enhancements for Magnetic Resonance Imaging Hardware and Software in a Clinical Setting

Evaluation of Thrombin Generation in Children with Venous Thromboembolism

Evaluation of the biochemical and Biophysical Properties of Meibomian lipid Samples collected From Meibomian Glands of normal Donors and Dry Eye Patients

Exercise in Burn Survivors

Exploring Immune Effects of Oral Insulin in Relatives at Risk for Type 1 Diabetes Mellitus TN20

Expression of co-inhibitory receptors in inflammatory disease and cancer

Factors associated with adolescent HPV vaccine use in UTSW and Parkland affiliated clinics

Family Studies of Sensorimotor and Neurocognitive Heterogeneity in Autism Spectrum Disorders (ASD)

Finding the Causes of Rare Skin Diseases

Functional myocardial ischemia as a mechanism for diastolic dysfunction in women with coronary microvascular dysfunction

Genetic Determinants of Keloid Formation Study

Genetic Determinations of Familial Chest Wall Abnormalities

Genetic Studies in Addiction

Genetic Variation in a Multi-Ethnic Population

Genetic and Biomarker Study of Alzheimer's Disease

Glucose Production After Ingesting 13C-Labeled Glycerol

H+-ATPase B-subunit Dysfunction and Calcium Nephrolithiasis

Health Topics Survey

Hippocampal Neurogenesis in Human Subjects (Pilot Study)

Hypertension and Antihypertensive Therapy in Elderly Women

INSPPIRE to Study Acute Recurrent and Chronic Pancreatitis in Children

Icariin to Prevent Corticosteroid-related Memory Changes

Identifying Biomarkers of GI Morbidity in Autism Spectrum Disorder (ASD): Linking Multi-omics and Human Behavior

Immunologic and Genetic Profiles in Subsets of Morphea Patients

In Vitro Effects of QuikClot Hemostatic Dressing on Anticoagulated Blood

LDL and Cholesterol Metabolism

Leveraging Technology To Provide The Next Generation of Clinical Connectivity

Mechanisms Underlying Asthma Exacerbations Prevented and Persistent with Immune-Based Therapy: A Systems Approach Phase 1

Mechanisms of Muscle Blood Flow Dysregulation and Exercise Intolerance in Chronic Kidney Disease

Micro-RNA Expression Profiling of Patients with Primary Immunodeficiency Diseases.

Mild Cognitive Impairment: Cerebrovascular Dysfunction and Exercise Training

Mitochondrial Function in Patients with Severe Liver Disease

Molecular Basis of Autosomal Dominant Hypercholesterolemia and Other Severe Dyslipidemias in a Multiethnic Cohort

Molecular Basis of Cholesterol Metabolism and Selected Other Genetic Disorders

Molecular Studies of Cutaneous Lupus

Molecular mechanisms of renal phosphate transport in human health and disease

Montreal Cognitive Assessment for Detection of MCI in African Americans

Multiple System Atrophy Multidisciplinary Clinic

Mutational Spectrum of Anterior Segment ophthalmic disorders

Nephrolithiasis in Patients with Primary Hyperparathyroidism

Neural Correlates of Effort Computation in Schizophrenia

Neural Mechanisms of Multiple Sclerosis Related Cognitive Change

Neural mechanisms of aldosterone-induced insulin resistance.

Neurobiology of Alzheimer's Disease and Aging - (Genetics of Dementing Brain Diseases)

Neutrophil Function in Cystic Fibrosis Patients

Non-Invasive Evaluation of Brain Oxygen Metabolism Using Magnetic Resonance Imaging

Optimization and Validation of Magnetic Resonance Imaging of Brown Adipose Tissue in Humans

Parkinsons Disease biomarkers program

Parkland-UT Southwestern PROSPR Center: Cervical Cancer screening in a safety net

Parkland-UT Southwestern PROSPR Center: Colon cancer screening in a safety net

Pathophysiology of Uric Acid Nephrolithiasis

Phenytoin for Memory Impairment Secondary to Megestrol

Philips Pivotal Clinical Trial for MRI-guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids

Physiological, Neural and Cognitive Bases of Age-Related Working Memory Change

Plasma ceramides and correlation with adiponectin levels in children and adolescents with type 2 diabetes.

Potential Role of Gastrointestinal Alkali Loss in Patients with Uric Acid Nephrolithiasis

Potential Role of Gastrointestinal Microflora in Increased Acid Production in Patients with Uric Acid Nephrolithiasis

Preventing Perinatal Depression (PRE-D): Developing Tools and Interventions

Procurement of Patient and Control Blood Samples for Deposit in a Cell/DNA Repository to Facilitate the Study of Disorders of Mineral Metabolism

Procurement of patient and control blood samples for a DNA repository to facilitate the study of metabolic diseases in the Advanced Imaging Research Center

Protocol HVTN 505: Phase 2b, randomized, placebo-controlled test-of-concept trial to evaluate the safety and efficacy of a multiclade HIV-1 DNA plasmid vaccine followed by a multiclade HIV-1 recombinant adenoviral vector vaccine in HIV-uninfected, adenovirus type 5 neutralizing antibody negative, circumcised men and male-to-female (MTF) transgender persons, who have sex with men

Psychiatry Clinical Research Infrastructure (P-CRI) Healthy Controls Database

Quantification of Volumetric Pulmonary Perfusion Using 3D Arterial Spin Labeled Perfusion MRI

Registry and Biorepository for the study of Inflammatory Bowel Disease

Registry for Asthma Characterization and Recruitment 2

Regulation of Renal Calcium Transport by Acid-Base and Magnesium

Representation of Facial Identity and View-point in the Ventral Temporal Cortex

Research to Evaluate an Effective Community-level Intervention for Young Black Men Who Have Sex with Men

Risk Factors Underlying Increased Susceptibility and Severity of Lupus Nephritis

SPRINT-MS (NN102) "A randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability and activity of ibudilast (MN-166) in subjects with progressive multiple sclerosis"

Shortness of Breath During Exertion in Obesity

Superior Fornix Depth After Traditional vs. Conjuctive Sparing Muller's Muscle Resection Surgery

TAMU-UT Southwestern Partnership for Breast Imaging and Spectroscopy at 7 Tesla

TDCS Enhanced Stroke Recovery and Cortical Reorganization

Technology Development for Mitochondrial Substrate Oxidation at 3 Tesla and 7 Tesla

Technology development for optimization of MRI protocols in the clinical and research setting

The Role Mitochondrial Dysfunction in Non-Alcoholic Fatty Liver Disease

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension

The University of Texas Southwestern Cardiology Clinical Research Database (CCRD) and Research Program

The effectiveness of contact lens care solutions on Pseudomonas biofilms formed in the presence of neutrophils

The relationship between brain iron accumulation and beta-amyloid deposition in middle-aged and older adults

Therapeutic Potential of EffCaMgCit During PPI Use: A Multi-dosing Study

UT Southwestern Liver Disease Repository and Registry

UTSW Depression Cohort: A Longitudinal Study of Depression

Utilizing Brain Imaging to Understand Cognitive Dysfunction in Transverse Myelitis

Validation of a Short Memory Tool (ECA) Designed Specifically for use During and After Electroconvulsive Therapy (ECT)

Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension

Visceral Adiposity and Diabetes: Translating Form to Function Using Imaging

Whole Blood Platelet Aggregation in Chronic Kidney Disease on Aspirin and Clopidogrel Study

Zimmerman Program for the Molecular and Clinical Biology of VWD