A Research Depository of Normal and Neoplastic Human Tissues
iii. SPeCiMen CoLLeCTion
We propose to systematically collect normal and neoplastic tissues obtained either at surgery or by medically indicated therapeutic or diagnostic procedures. only those tissues not required for patient management or evaluation will be collected. Small volumes of blood would be collected to provide convenient access to normal blood cells and to serum constituents. Clinical information will be collected from the patient, the medical record, or the attending physician for inclusion into a computer database system. only coded data after removal of patient identifiers will be available for research purposes.
iV. eLiGiBiLiTY CRiTeRia
adult cancer patients as well as all adult inpatients and outpatients would be eligible for inclusion.
Candidates must possess the ability to give informed consent.
eligible candidates may include cancer patients, adult inpatients and outpatients, healthy volunteers, patients undergoing cosmetic removal of various tissues such as reduction mammoplasty.
in addition, patients with preneoplastic lesions or inherited cancer syndromes may be studied.
V. CRiTeRia FoR eXCLuSion oF SuBJeCTS
inability to give informed consent.
Children, we will not recruit minors as participants for this study.
Blood or fresh tissue will not be collected from patients with known HiV positivity.
Further, blood or fresh tissues will not be collected from patients with known Hepatitis B or Hepatitis C positivity.
Subjects with cancer and healthy volunteers. All subjects must be capable of giving informed consent.