BIPOLAR-SCHIZOPHRENIA NETWORK FOR INTERMEDIATE PHENOTYPES: PSYCHOSIS AND AFFECTIVE RESEARCH DOMAINS

Study ID
STU 072013-063

Cancer Related
No

Healthy Volunteers
Yes

Study Sites

Contact
Asha Philip
214-648-5276
asha.philip@utsouthwestern.edu

Principal Investigator
Carol Tamminga

Summary

The objective of this multisite research collaboration (Bipolar-Schizophrenia network on intermediate Phenotypes, B-SniP) is to test the manifestation and distribution of biological markers for psychosis and affect dimensions across the SZ-BD diagnostic boundary, and to examine heritability and genetic associations for these biological markers.

Participant Eligibility


* Must provide consent to participate after being fully informed about the study procedures and the information to be collected

* Males and females

* Ages 18-60 years old

* All races and ethnicities

* Probands: Must meet DSM criteria for schizophrenia, schizoaffective disorder, or bipolar I disorder with or without lifetime history of psychosis; Relatives: Must have at least one biological first-degree relative with schizophrenia, schizoaffective disorder, or bipolar I disorder with or without lifetime history of psychosis; Healthy Controls: Must have no personal history of any psychotic or mood disorder, or a family history of psychotic or recurrent mood disorder among their first-degree relatives

* Must be judged to be capable of completing the study procedures by study investigators

* Must be able to read, speak, and understand English