Multi Center Prospective Analysis of Treatment Outcome in Patients with Large Acoustic Neuromas Receiving Subtotal Resection with Backup Stereotactic Radiation Therapy (A.N.S.R.S)
Prospective, non-randomized, multi-centered. This study involves benign acoustic neuromas. Subjects would be thoroughly evaluated by the Pi during the clinic visit. Data is collected in terms of tumor size, symptoms, hearing test and MRi findings. Subjects then would undergo surgical treatment, radiologic treatment or no treatment and careful follow-up. Subjects will be followed in the Pi's clinic as a part of routine follow-up appointments at 1mo, 3mo, 6mo, 12 months and then annaully after surgery. MRi's would be obtained within 1 month, at 6 months and then annually as per standard of care. The data collected from surgery, hospital stay and clinic visit is part of standard of practice such as operative time, length of hospital stay, symptoms and complications after surgery. Stereotactic radiation may be used for controlling tissue growth where benign tumors are on the hearing nerve in an attempt to preserve function of the nerves in that area. it is usually one or two treatments.
The study also involves a retrospective collection of data for patients that are being followed routinely in the clinic and consent to participate during a routine follow-up visit.
1.Any previously untreated acoustic neuroma with maximal diameter > or = 2.5 cm in the cerebellopontine angle 2.May be sporadic or NF-2 associated 3.Adult patients greater than 18 years of age. 4.Any patient with whom the surgeon has discussed the possibility of a subtotal resection with or without Stereotactic Radiation Therapy (SRT) for remnant control prior to surgery could be enrolled in the study as long as comoplete data is available for follow up, regradless of amount of tumor resected
Data collected will include MRIs, audiograms, operative reports, pathology reports, anesthesia records, Dizziness Handicap Inventory, patient demographic sheets, and clinic intake sheet.