Tissue Procurement and Outcome Collection for Radiotherapy Treated Patients

Study ID
STU 072010-098

Cancer Related
Yes

Healthy Volunteers
No

Study Sites

Contact
Suprabha Pulipparacharuvil
214-633-1752
suprabha.pulipparacharuvil@utsouthwestern.edu

Principal Investigator
Hak Choy

Summary

Tissue samples and data will be collected from patients diagnosed with cancer who are to be or have been treated with radiation therapy. The samples and data will be put into the uT Southwestern Radiation oncology Tissue Resource and Registry Database. The samples will aid in exploring genetic variations contributing to clinical outcomes through tissue analysis and outcome correlation. Tissue research could one day be used to predict the risk of severe complications from radiation therapy in patients and help design more individualized, effective and safer treatment plans.

Subjects will be patients of the uT Southwestern Medical Center, Moncrief Cancer Center, uT Southwestern university Hospitals (St Paul and Zale-Lipshy) and Parkland. annual patient accrual is anticipated to be 500. Follow up will be at physician discretion, but at least every 6 months for the first two years, then yearly thereafter until death or withdrawal.

Participant Eligibility

3.1 Criteria for eligibility
3.1.1 Able to provide written informed consent
3.1.2 Pathologically proven malignancy
3.1.3 Age greater than 18 years old
3.1.4 Patients who plan to or have undergone other therapy for their cancer, such as surgery and/or chemotherapy and/or Radiotherapy, and those who are in the follow up.
3.1.5 Males and Females are eligible
3.1.6 Any ethnicity is eligible