Predicting Treatment Response for Cervical Cancer: Assessment Using BOLD MRI

Study ID
STU 072010-014

Cancer Related

Healthy Volunteers

Study Sites

  • Clements University Hospital
  • Parkland Health & Hospital System

Isabel Villalobos

Principal Investigator
Ralph Mason, Ph.D.


This is a study of the use of BoLD MRi to determine the amount of oxygen supply to cervical tumors. This information will be correlated with the participants' response to therapy. MRi spectroscopy and Dynamic Contrast enhanced (DCe) MRi will also be performed to correlate with more traditional examinations (physical exams, CT scans and standard MRi scans). We hypothesize that the use of BoLD MRi can provide a non-invasive tool to examine tumor oxygenation and improve treatment planning.

We plan to enroll 35 subjects onto this study at Parkland Health and Hospital System; this is not a multi-center study.

Participant Eligibility

1.18 years or older.
2.Subject is female.
3.Subject has biopsy proven cervical cancer.
4.Stage II x IV A cervical cancer
5.Patients must have a GOG Performance Status of 0, 1 or 2.
6.Measure of disease should be a target lesion.
7.Patients must have signed an approved informed consent.
8.Spanish-speaking subjects are eligible for participation.