Outcomes in Acute Gastrointestinal Bleeding
1. Epidemiologic factors (in particular ethnicity) may be important in not only the frequency of UGIH, but also outcomes. We will use ethnicity factor to identify if it has impact on upper gastrointestinal bleed diagnosis and whether morbidity and mortality will be affected depending on it.
2. Therapeutic intervention such as epinephrine in combination with hemoclip and/or thermal coagulation at higher doses will lead to a reduction in the number of upper gastrointestinal rebleeding events.
3. Anticoagulation (on the following medications: plavix, coumadin, heparin) will not have an effect on endoscopic findings, therapy or rebleeding events.
4. Early endoscopy in acute UGIH will lead to a shorter length of hospital stay, decrease transfusion requirements, need for surgery, and better outcomes.
This is a retrospective cohort study that proposes to utilize the GI Healthcare Operations Registry to answer several important questions identified under the hypothesis section. We will evaluate patient epidemiology, time to endoscopy, anticoagulation and therapeutic interventions. We will assess endoscopic findings, therapy, rebleeding events, and analyze for any changes in outcomes relating to morbidity and mortality. In addition, several variables will be collected that are listed below under variable section. This study will include patients from July 2006-August 31, 2011. An estimated 3000 patient charts will be identified using the GI Healthcare Operations Registry.
Any patient identified with UGI bleed from July 1, 2006 to August 31, 2011 at Parkland Memorial Hospital. Subjects will be solely identified from the GI Healthcare Registry, If any variables are missing from the GI Healthcare Registry database, only then we will access electronic medical records to look up missing data to answer the study question. No additional variables will be collected or used during this retrospective review.