Database registry to Examine Brain Connections and Brain Function in Mental Disorders and Neural Network Biomarkers for Relational Memory and Psychosis in Schizophrenia

Study ID
STU 062010-095

Cancer Related
No

Healthy Volunteers
Yes

Study Sites

  • Clements University Hospital
  • UT Southwestern Ambulatory Services
  • Parkland Health & Hospital System

Contact
Tanusree Das
214/645-2565
tanusree.das@utsouthwestern.edu

Principal Investigator
Carol Tamminga

Summary

This database registry will allow for the collection of clinical interview data, behavioral data, blood, magnetic resonance imaging (MRi) data, and functional magnetic resonance imaging (fMRi) data on individuals with and without mental disorders and/or neurological disorders to better understand how connections in the brain and various brain regions function differently while volunteers perform various cognitive tasks. This is an observational study that is being conducted to collect data and place it in a registry for current and future investigational questions related to imaging in mental disorders.

Participant Eligibility

Volunteers with schizophrenia or other mental illness or certain types of neurological disorders, such as epilepsy:

* DSM-IV diagnosis of schizophrenia or other mental illness or specified neurological disorder

* Competent to give informed consent

* Males and females

* Ages 15-70 years old

* All races and ethnicities

* Eyesight corrected to 20-40 or better

* Able to read, speak, and understand English*

Volunteers that are biological first degree relatives of individuals with schizophrenia or other mental illness

* Males and females

* Ages 15-70 years old

* All races and ethnicities

* Eyesight corrected to 20-40 or better

* Able to read, speak, and understand English*

Healthy volunteers

* Males and females

* Ages 15-70 years old

* All races and ethnicities

* Eyesight corrected to 20-40 or better

* Able to read, speak, and understand English*