Genetic Studies in Addiction

Study ID
STU 062010-081

Cancer Related

Healthy Volunteers

Study Sites

  • UT Southwestern-Other
  • UT Southwestern-Clinical Translational Research Center (CTRC)

Ingrid Kepinski
214 645 6901

Principal Investigator
Bryon Adinoff, M.D.


Both alcohol- and drug-addicted subjects as well as healthy controls will be asked to participate in this study. only one study visit will be required of participants and during this visit, 2 and [1/2]) tablespoons of blood will be collected. Plasma samples for Dna will be coded and immediately sent to the eugene McDermott Center for Growth and Development at university of Texas Southwestern Medical Center. Samples will have their Dna banked in a secure freezer with coded identification. When a large enough number of samples have been acquired, candidate genes have been suitably refined, and SnP chips become commercially available, appropriate pathways and candidate genes will be assessed via SnP chips and associated with previously assessed behaviors, personality styles, and/or biologic responses.

Participant Eligibility

1. Subjects will be age 18 or older of any race and of either gender.
2. Subjects must have a diagnosis of a substance abuse disorder or have no present or past history of a substance use disorder (healthy controls).
3. Healthy controls may be included if they have a nicotine dependence disorder.
4. Subjects must be able to provide informed consent.
5. Subjects will not be under the influence of substances that may limit judgment and ability to provide informed consent.