Breast Cancer Rehabilitation Improving Daily Function and Participation

Study ID
STU 032012-031

Cancer Related
Yes

Healthy Volunteers
No

Study Sites

Contact
Lindsey Rose
214-648-1789
lindsey.rose@utsouthwestern.edu

Principal Investigator
Lindsey Rose

Summary

Research design: Survey study (descriptive research design), using a survey packet based on the iCF model to measure multiple factors related to BC survivors' functioning, disability, and Health.
independent variables and outcome variables are as below:
(1) Demographic variables: (the study will only recruit females with BC at stage i, ii and iii.) Variables are chemotherapy dosage, age, race, education, employment, working hours, income, BMi and waist-hip ratio, etc.
(2) iCF model variables:
* Health outcome measures (outcome variables): the SF-12/ Satisfaction With Life/ Sense of Coherence
* Body function measures (variables): Secondary Condition Surveillance instrument/ the Cognitive Failure Questionnaire/ the Pain intensity Scale/ the Patient Health Questionnaire/ the General anxiety Disorder
* activity/physical functioning domain measures (outcome variables): the daily functional physical activity scale/ the iPaQ/ Pa Stages of Change
* Participation measures (outcome variables): Gray's Participation Survey/ Brakel's participation measures/ the WHo Disability assessment
* environmental measures (variables): Barriers to Health Promotion Scale/ Multidimensional Scale of Perceived Social Support/ the Stigma Scale for Chronic illness
* Personal factors measures of positive traits measures (variables): Brief CoPe/ the Connor-Davidson Resilience Scale/ the Perceived Stress scale
in 2011, there were 1.53 million estimated new cancer cases and 569,490 cancer deaths. The increase in cancer cases has been attributed to lifestyle factors, such as physical inactivity, diet and tobacco. over the past 10 years, the breast cancer (BC) 5-year survival rate has ranged from 80%- 98% for early stage cancers (Stage 0-iii), due to improvements in screenings, surgeries and adjuvant treatments. aside from these promising statistics, BC patients are faced with a plethora of significant biopsychosocial deficits ,due to the BC diagnosis and treatments (surgery and especially chemotherapy), that cause functional impairment and disability, as well as an economic burden. This burden can further affect a BC patient's roles and obligations with her husband/partner, children, and ability to maintain financial security/savings (e.g., job loss or decreased productivity and quality of work). The WHo's international Classification of Functioning, Disability and Health Model (iCF) has been developed for comprehensively addressing an individual's biopsychosocial health, using daily functional activity and life role performance participation in the community (e.g., worker, parent, spouse), as facilitators to encourage people to pursue physically-active lifestyles in their daily lives. However, there is a paucity of research using the iCF to study how the BC patient's biopsychosocial functioning is affected in pre-, during- and post phases of chemotherapy in the areas of the patient's daily functioning and participation in their various roles (e.g., work). The proposed project's aim1 is to understand BC patients' health in three phases of chemotherapy (i.e., pre-, during- and post-) based on the iCF. a new psychometrically-validated battery, in accordance with the iCF domains, will be used to survey BC patients' health in three phases of chemotherapy. The main analysis methods will be structural equation modeling and hierarchal regression. We hypothesize that the iCF-based biopsychosocial health model will statistically fit BC patients' health outcomes, and the model will examine the strength of structural relationships among constructs in three phases of chemotherapy. additionally, aim 2 of the proposed project will validate a daily functional physical activity (DF-Pa) scale to assess BC patients' daily functional physical activity. The proposed project will examine the reliability, as well as the convergent and discriminant validity of our previously piloted DF-Pa scale (with participants with spinal cord injury), but now with BC patients.

Participant Eligibility

1. Diagnosis with breast cancer from stage 1-3
2. Female adults, 18-64 years old
3. Able to speak, listen and read in English
4. Will start to receive chemotherapy, or
5. Still have chemotherapy (you are still in chemotherapy), or
6. Already have completed chemotherapy after 4 months to 5 years